Edmond Chan
Edmond Chan
Assistant Professor, Queen's University Dept Biomed. Mol Sci
Verified email at queensu.ca
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, ...
Autophagy 4 (2), 151-175, 2008
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
ARJ Young, EYW Chan, XW Hu, R Köchl, SG Crawshaw, S High, ...
Journal of cell science 119 (18), 3888-3900, 2006
RasGRP, a Ras guanyl nucleotide-releasing protein with calcium-and diacylglycerol-binding motifs
JO Ebinu, DA Bottorff, EYW Chan, SL Stang, RJ Dunn, JC Stone
Science 280 (5366), 1082-1086, 1998
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1, 4, 5) triphosphate receptor type 1
TS Tang, H Tu, EYW Chan, A Maximov, Z Wang, CL Wellington, ...
Neuron 39 (2), 227-239, 2003
Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes
R Köchl, XW Hu, EYW Chan, SA Tooze
Traffic 7 (2), 129-145, 2006
siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy
EYW Chan, S Kir, SA Tooze
Journal of Biological Chemistry 282 (35), 25464-25474, 2007
Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism
EYW Chan, A Longatti, NC McKnight, SA Tooze
Molecular and cellular biology 29 (1), 157-171, 2009
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain
R Luthi-Carter, SA Hanson, AD Strand, DA Bergstrom, W Chun, NL Peters, ...
Human molecular genetics 11 (17), 1911-1926, 2002
Early endosomes and endosomal coatomer are required for autophagy
M Razi, EYW Chan, SA Tooze
Journal of Cell Biology 185 (2), 305-321, 2009
mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex
EY Chan
Science signaling 2 (84), pe51-pe51, 2009
Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease
EYW Chan, R Luthi-Carter, A Strand, SM Solano, SA Hanson, ...
Human molecular genetics 11 (17), 1939-1951, 2002
Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo
SC Warby, EY Chan, M Metzler, L Gan, RR Singaraja, SF Crocker, ...
Human molecular genetics 14 (11), 1569-1577, 2005
Regulation of nutrient-sensitive autophagy by uncoordinated 51-like kinases 1 and 2
F McAlpine, LE Williamson, SA Tooze, EYW Chan
Autophagy 9 (3), 361-373, 2013
Evolution of Atg1 function and regulation
EY Chan, SA Tooze
Autophagy 5 (6), 758-765, 2009
Advances in autophagy regulatory mechanisms
LE Gallagher, LE Williamson, EYW Chan
Cells 5 (2), 24, 2016
Targeted disruption of Huntingtin-associated protein-1 (Hap1) results in postnatal death due to depressed feeding behavior
EYW Chan, J Nasir, CA Gutekunst, S Coleman, A Maclean, A Maas, ...
Human molecular genetics 11 (8), 945-959, 2002
A novel pathway for tumor necrosis factor-α and ceramide signaling involving sequential activation of tyrosine kinase, p21 ras, and phosphatidylinositol 3-kinase
AN Hanna, EYW Chan, J Xu, JC Stone, DN Brindley
Journal of Biological Chemistry 274 (18), 12722-12729, 1999
Regulation and function of uncoordinated-51 like kinase proteins
EY Chan
Antioxidants & redox signaling 17 (5), 775-785, 2012
HAP1 facilitates effects of mutant huntingtin on inositol 1,4,5‐trisphosphate‐induced Ca2+ release in primary culture of striatal medium spiny neurons
TS Tang, H Tu, PC Orban, EYW Chan, MR Hayden, I Bezprozvanny
European Journal of Neuroscience 20 (7), 1779-1787, 2004
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