The role of cholesterol in the biosynthesis of β-amyloid. ER Frears, DJ Stephens, CE Walters, H Davies, BM Austen Neuroreport 10 (8), 1699-1705, 1999 | 465 | 1999 |
5 Glutamate dehydrogenases EL Smith, BM Austen, KM Blumenthal, JF Nyc The enzymes 11, 293-367, 1975 | 435 | 1975 |
Trypsinogen activation peptides assay in the early prediction of severity of acute pancreatitis AM Gudgeon, P Hurley, A Jehanli, G Patel, BM Austen, J Hermon-Taylor, ... The Lancet 335 (8680), 4-8, 1990 | 324 | 1990 |
Oligomerization and toxicity of β-amyloid-42 implicated in Alzheimer's disease OMA El-Agnaf, DS Mahil, BP Patel, BM Austen Biochemical and biophysical research communications 273 (3), 1003-1007, 2000 | 214 | 2000 |
Predicted secondary structures of amino‐terminal extension sequences of secreted proteins BM Austen FEBS letters 103 (2), 308-313, 1979 | 202 | 1979 |
Profiling of amyloid beta peptide variants using SELDI Protein Chip arrays. H Davies, L Lomas, B Austen Biotechniques 27 (6), 1258-1261, 1999 | 176 | 1999 |
Designing peptide inhibitors for oligomerization and toxicity of Alzheimer's β-amyloid peptide BM Austen, KE Paleologou, SAE Ali, MM Qureshi, D Allsop, ... Biochemistry 47 (7), 1984-1992, 2008 | 156 | 2008 |
Development of radioimmunoassays for free tetra-L-aspartyl-L-lysine trypsinogen activation peptides (TAP) PR Hurley, A Cook, A Jehanli, BM Austen, J Hermon-Taylor Journal of immunological methods 111 (2), 195-203, 1988 | 117 | 1988 |
γ Endorphin, α endorphin and met-enkephalin are formed extracellularly from lipotropin C fragment BM Austen, DG Smyth, CR Snell Nature 269 (5629), 619-621, 1977 | 111 | 1977 |
The use of Seldi ProteinChip™ Arrays to monitor production of Alzheimer's β‐amyloid in transfected cells BM Austen, ER Frears, H Davies Journal of peptide science: an official publication of the European Peptide …, 2000 | 103 | 2000 |
Non-fibrillar oligomeric species of the amyloid ABri peptide, implicated in familial British dementia, are more potent at inducing apoptotic cell death than protofibrils or … OMA El-Agnaf, S Nagala, BP Patel, BM Austen Journal of molecular biology 310 (1), 157-168, 2001 | 100 | 2001 |
Galantamine inhibits β-amyloid aggregation and cytotoxicity B Matharu, G Gibson, R Parsons, TN Huckerby, SA Moore, LJ Cooper, ... Journal of the neurological sciences 280 (1-2), 49-58, 2009 | 99 | 2009 |
Amyloid-β acts as a regulator of neurotransmitter release disrupting the interaction between synaptophysin and VAMP2 CL Russell, S Semerdjieva, RM Empson, BM Austen, PW Beesley, ... PloS one 7 (8), e43201, 2012 | 88 | 2012 |
The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors RB Parsons, S Aravindan, A Kadampeswaran, EA Evans, KK Sandhu, ... Biochemical Journal 436 (1), 145-155, 2011 | 76 | 2011 |
Oligomerization of β-amyloid of the Alzheimer’s and the Dutch-cerebral-haemorrhage types AK Sian, ER Frears, OMA El-Agnaf, BP Patel, MF Manca, G Siligardi, ... Biochemical Journal 349 (1), 299-308, 2000 | 76 | 2000 |
Action of stapeylococcal proteinase on peptides of varying chain length and composition BM Austen, EI Smith Biochemical and biophysical research communications 72 (2), 411-417, 1976 | 68 | 1976 |
Heat shock proteins induce pores in membranes GM Alder, BM Austen, CL Bashford, A Mehlert, CA Pasternak Bioscience reports 10 (6), 509-518, 1990 | 66 | 1990 |
The NH2-terminus of C-fragment is resistant to the action of aminopeptidases BM Austen, DG Smyth Biochemical and biophysical research communications 76 (2), 477-482, 1977 | 59 | 1977 |
Statins inhibit the dimerization of β-secretase via both isoprenoid-and cholesterol-mediated mechanisms RB Parsons, GC Price, JK Farrant, D Subramaniam, J Adeagbo-Sheikh, ... Biochemical Journal 399 (2), 205-214, 2006 | 54 | 2006 |
Design and synthesis of a consensus signal sequence that inhibits protein translocation into rough microsomal vesicles BM Austen, J Hermon-Taylor, MA Kaderbhai, DH Ridd Biochemical Journal 224 (1), 317-325, 1984 | 54 | 1984 |