Mutations of the BRAF gene in human cancer H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ... Nature 417 (6892), 949-954, 2002 | 12675 | 2002 |
Patterns of somatic mutation in human cancer genomes C Greenman, P Stephens, R Smith, GL Dalgliesh, C Hunter, G Bignell, ... Nature 446 (7132), 153-158, 2007 | 3738 | 2007 |
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer SA Forbes, N Bindal, S Bamford, C Cole, CY Kok, D Beare, M Jia, ... Nucleic acids research 39 (suppl_1), D945-D950, 2010 | 2677 | 2010 |
Massive genomic rearrangement acquired in a single catastrophic event during cancer development PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ... cell 144 (1), 27-40, 2011 | 2583 | 2011 |
Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 2173 | 2016 |
Mutational processes molding the genomes of 21 breast cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012 | 2061 | 2012 |
A comprehensive catalogue of somatic mutations from a human cancer genome ED Pleasance, RK Cheetham, PJ Stephens, DJ McBride, SJ Humphray, ... Nature 463 (7278), 191-196, 2010 | 2014 | 2010 |
The landscape of cancer genes and mutational processes in breast cancer PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ... Nature 486 (7403), 400-404, 2012 | 1910 | 2012 |
High burden and pervasive positive selection of somatic mutations in normal human skin I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ... Science 348 (6237), 880-886, 2015 | 1705 | 2015 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1682* | 2020 |
The patterns and dynamics of genomic instability in metastatic pancreatic cancer PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ... Nature 467 (7319), 1109-1113, 2010 | 1558 | 2010 |
The life history of 21 breast cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012 | 1550 | 2012 |
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ... Nature 469 (7331), 539-542, 2011 | 1391 | 2011 |
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes GL Dalgliesh, K Furge, C Greenman, L Chen, G Bignell, A Butler, ... Nature 463 (7279), 360-363, 2010 | 1351 | 2010 |
A small-cell lung cancer genome with complex signatures of tobacco exposure ED Pleasance, PJ Stephens, S O’Meara, DJ McBride, A Meynert, D Jones, ... Nature 463 (7278), 184-190, 2010 | 1278 | 2010 |
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing PJ Campbell, PJ Stephens, ED Pleasance, S O'Meara, H Li, T Santarius, ... Nature genetics 40 (6), 722-729, 2008 | 977 | 2008 |
Intragenic ERBB2 kinase mutations in tumours P Stephens, C Hunter, G Bignell, S Edkins, H Davies, J Teague, ... Nature 431 (7008), 525-526, 2004 | 944 | 2004 |
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ... Nature genetics 41 (5), 521-523, 2009 | 925 | 2009 |
Subclonal diversification of primary breast cancer revealed by multiregion sequencing LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ... Nature medicine 21 (7), 751-759, 2015 | 836 | 2015 |
A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation PS Tarpey, R Smith, E Pleasance, A Whibley, S Edkins, C Hardy, ... Nature genetics 41 (5), 535-543, 2009 | 681 | 2009 |