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G. Vignir Helgason
G. Vignir Helgason
Wolfson Wohl Cancer Research Centre
Verified email at Glasgow.ac.uk - Homepage
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Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
106722021
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
DJ Klionsky, H Abeliovich, P Agostinis, DK Agrawal, G Aliev, DS Askew, ...
Autophagy 4 (2), 151-175, 2008
3091*2008
Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells
C Bellodi, MR Lidonnici, A Hamilton, GV Helgason, AR Soliera, ...
The Journal of clinical investigation 119 (5), 1109-1123, 2009
6812009
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival
A Hamilton, GV Helgason, M Schemionek, B Zhang, S Myssina, EK Allan, ...
Blood, The Journal of the American Society of Hematology 119 (6), 1501-1510, 2012
4872012
Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells
EM Kuntz, P Baquero, AM Michie, K Dunn, S Tardito, TL Holyoake, ...
Nature medicine 23 (10), 1234-1240, 2017
4582017
The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML
D Vetrie, GV Helgason, M Copland
Nature Reviews Cancer 20 (3), 158-173, 2020
2362020
Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/− knock-outs compared with wild-type mice
M Bjarnadottir, DL Misner, S Haverfield-Gross, S Bruun, VG Helgason, ...
Journal of Neuroscience 27 (17), 4519-4529, 2007
2222007
Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML
GV Helgason, M Karvela, TL Holyoake
Blood, The Journal of the American Society of Hematology 118 (8), 2035-2043, 2011
1502011
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors
P Baquero, A Dawson, A Mukhopadhyay, EM Kuntz, R Mitchell, ...
Leukemia 33 (4), 981-994, 2019
1182019
ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells
M Karvela, P Baquero, EM Kuntz, A Mukhopadhyay, R Mitchell, EK Allan, ...
Autophagy 12 (6), 936-948, 2016
1072016
The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors
F Pellicano, MT Scott, GV Helgason, LEM Hopcroft, EK Allan, ...
Stem cells 32 (9), 2324-2337, 2014
982014
Targeting BCR-ABL-independent TKI resistance in chronic myeloid leukemia by mTOR and autophagy inhibition
R Mitchell, LEM Hopcroft, P Baquero, EK Allan, K Hewit, D James, ...
JNCI: Journal of the National Cancer Institute 110 (5), 467-478, 2018
952018
Mitochondrial metabolism as a potential therapeutic target in myeloid leukaemia
L de Beauchamp, E Himonas, GV Helgason
Leukemia 36 (1), 1-12, 2022
702022
Autophagy in blood cancers: biological role and therapeutic implications
A Nencioni, M Cea, F Montecucco, VD Longo, F Patrone, AM Carella, ...
haematologica 98 (9), 1335, 2013
702013
Folate metabolism: a re-emerging therapeutic target in haematological cancers
MM Zarou, A Vazquez, G Vignir Helgason
Leukemia 35 (6), 1539-1551, 2021
592021
Utilizing stimulated Raman scattering microscopy to study intracellular distribution of label-free ponatinib in live cells
K Sepp, M Lee, MTJ Bluntzer, GV Helgason, AN Hulme, VG Brunton
Journal of medicinal chemistry 63 (5), 2028-2034, 2019
592019
The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells
F Pellicano, P Šimara, A Sinclair, GV Helgason, M Copland, S Grant, ...
Leukemia 25 (7), 1159-1167, 2011
592011
Role of autophagy in cancer prevention, development and therapy
GV Helgason, TL Holyoake, KM Ryan
Essays in biochemistry 55, 133-151, 2013
562013
A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease
GA Horne, J Stobo, C Kelly, A Mukhopadhyay, AL Latif, J Dixon-Hughes, ...
Leukemia 34 (7), 1775-1786, 2020
552020
Autophagy in chronic myeloid leukaemia: stem cell survival and implication in therapy
G V Helgason, A Mukhopadhyay, M Karvela, P Salomoni, B Calabretta, ...
Current cancer drug targets 13 (7), 724-734, 2013
482013
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