| The role of toxin A and toxin B in Clostridium difficile infection SA Kuehne, ST Cartman, JT Heap, ML Kelly, A Cockayne, NP Minton Nature 467 (7316), 711-713, 2010 | 935 | 2010 |
| The ClosTron: mutagenesis in Clostridium refined and streamlined JT Heap, SA Kuehne, M Ehsaan, ST Cartman, CM Cooksley, JC Scott, ... Journal of microbiological methods 80 (1), 49-55, 2010 | 505 | 2010 |
| Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile T Ðapa, R Leuzzi, YK Ng, ST Baban, R Adamo, SA Kuehne, M Scarselli, ... Journal of bacteriology 195 (3), 545-555, 2013 | 312 | 2013 |
| Importance of Toxin A, Toxin B, and CDT in Virulence of an Epidemic Clostridium difficile Strain SA Kuehne, MM Collery, ML Kelly, ST Cartman, A Cockayne, NP Minton The Journal of infectious diseases 209 (1), 83-86, 2014 | 250 | 2014 |
| The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia CA Cowardin, EL Buonomo, MM Saleh, MG Wilson, SL Burgess, ... Nature microbiology 1 (8), 1-10, 2016 | 179 | 2016 |
| Functional Intestinal Bile Acid 7α-Dehydroxylation by Clostridium scindens Associated with Protection from Clostridium difficile Infection in a Gnotobiotic Mouse … N Studer, L Desharnais, M Beutler, S Brugiroux, MA Terrazos, L Menin, ... Frontiers in cellular and infection microbiology 6, 191, 2016 | 173 | 2016 |
| The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain ST Baban, SA Kuehne, A Barketi-Klai, ST Cartman, ML Kelly, KR Hardie, ... PloS one 8 (9), e73026, 2013 | 169 | 2013 |
| The emergence of ‘hypervirulence’in Clostridium difficile ST Cartman, JT Heap, SA Kuehne, A Cockayne, NP Minton International Journal of Medical Microbiology 300 (6), 387-395, 2010 | 160 | 2010 |
| The role of calcium ion release on biocompatibility and antimicrobial properties of hydraulic cements A Koutroulis, SA Kuehne, PR Cooper, J Camilleri Scientific Reports 9 (1), 19019, 2019 | 112 | 2019 |
| Both, toxin A and toxin B, are important in Clostridium difficile infection. SA Kuehne, ST Cartman, NP Minton Gut microbes 2 (4), 252-255, 2011 | 107 | 2011 |
| The role of flagella in Clostridium difficile pathogenicity E Stevenson, NP Minton, SA Kuehne Trends in microbiology 23 (5), 275-282, 2015 | 103 | 2015 |
| Functional analysis of the post-transcriptional regulator RsmA reveals a novel RNA-binding site S Heeb, SA Kuehne, M Bycroft, S Crivii, MD Allen, D Haas, M Cámara, ... Journal of molecular biology 355 (5), 1026-1036, 2006 | 95 | 2006 |
| Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivo JT Heap, J Theys, M Ehsaan, AM Kubiak, L Dubois, K Paesmans, ... Oncotarget 5 (7), 1761, 2014 | 86 | 2014 |
| ClosTron-mediated engineering of Clostridium SA Kuehne, NP Minton Bioengineered 3 (4), 247-254, 2012 | 84 | 2012 |
| Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism (s) NV Jafari, SA Kuehne, CE Bryant, M Elawad, BW Wren, NP Minton, ... PloS one 8 (7), e69846, 2013 | 83 | 2013 |
| Which parameters affect biofilm removal with acoustic cavitation? A review N Vyas, K Manmi, Q Wang, AJ Jadhav, M Barigou, RL Sammons, ... Ultrasound in medicine & biology 45 (5), 1044-1055, 2019 | 71 | 2019 |
| Entry of spores into intestinal epithelial cells contributes to recurrence of Clostridioides difficile infection P Castro-Córdova, P Mora-Uribe, R Reyes-Ramírez, G Cofré-Araneda, ... Nature communications 12 (1), 1140, 2021 | 66 | 2021 |
| Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile CA Cowardin, SA Kuehne, EL Buonomo, CS Marie, NP Minton, ... MBio 6 (1), 10.1128/mbio. 02386-14, 2015 | 65 | 2015 |
| A sequence-based approach for prediction of CsrA/RsmA targets in bacteria with experimental validation in Pseudomonas aeruginosa PR Kulkarni, T Jia, SA Kuehne, TM Kerkering, ER Morris, MS Searle, ... Nucleic acids research 42 (11), 6811-6825, 2014 | 65 | 2014 |
| ClosTron-targeted mutagenesis JT Heap, ST Cartman, SA Kuehne, C Cooksley, NP Minton Clostridium difficile: Methods and Protocols, 165-182, 2010 | 60 | 2010 |
