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Thomas P. Mathews
Thomas P. Mathews
Assistant Professor, UT Southwestern Medical center
Verified email at utsouthwestern.edu
Title
Cited by
Cited by
Year
Lymph protects metastasizing melanoma cells from ferroptosis
JM Ubellacker, A Tasdogan, V Ramesh, B Shen, EC Mitchell, ...
Nature 585 (7823), 113-118, 2020
5622020
Metabolic heterogeneity confers differences in melanoma metastatic potential
A Tasdogan, B Faubert, V Ramesh, JM Ubellacker, B Shen, A Solmonson, ...
Nature 577 (7788), 115-120, 2020
3502020
Biomarkers of NAFLD progression: A lipidomics approach to an epidemic1 [S]
DL Gorden, DS Myers, PT Ivanova, E Fahy, MR Maurya, S Gupta, J Min, ...
Journal of lipid research 56 (3), 722-736, 2015
3322015
Drugs for allosteric sites on receptors
CJ Wenthur, PR Gentry, TP Mathews, CW Lindsley
Annual review of pharmacology and toxicology 54, 165-184, 2014
2652014
Association of acute toxic encephalopathy with litchi consumption in an outbreak in Muzaffarpur, India, 2014: a case-control study
A Shrivastava, A Kumar, JD Thomas, KF Laserson, G Bhushan, MD Carter, ...
The Lancet Global Health 5 (4), e458-e466, 2017
1122017
Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells
AJ Kennedy, TP Mathews, Y Kharel, SD Field, ML Moyer, JE East, ...
Journal of medicinal chemistry 54 (10), 3524-3548, 2011
972011
Sum of the parts: mass spectrometry-based metabolomics
SB Milne, TP Mathews, DS Myers, PT Ivanova, HA Brown
Biochemistry 52 (22), 3829-3840, 2013
842013
Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate
Y Kharel, TP Mathews, AM Gellett, JL Tomsig, PC Kennedy, ML Moyer, ...
Biochemical Journal 440 (3), 345-353, 2011
782011
Discovery, biological evaluation, and structure− activity relationship of amidine based sphingosine kinase inhibitors
TP Mathews, AJ Kennedy, Y Kharel, PC Kennedy, O Nicoara, M Sunkara, ...
Journal of medicinal chemistry 53 (7), 2766-2778, 2010
752010
Compartmentalized metabolism supports midgestation mammalian development
A Solmonson, B Faubert, W Gu, A Rao, MA Cowdin, I Menendez-Montes, ...
Nature 604 (7905), 349-353, 2022
582022
Metabolomic profiling of rare cell populations isolated by flow cytometry from tissues
AW DeVilbiss, Z Zhao, MS Martin-Sandoval, JM Ubellacker, A Tasdogan, ...
Elife 10, e61980, 2021
582021
Reactive metabolite production is a targetable liability of glycolytic metabolism in lung cancer
A Luengo, KL Abbott, SM Davidson, AM Hosios, B Faubert, SH Chan, ...
Nature communications 10 (1), 5604, 2019
522019
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ...
Cancer cell 40 (9), 939-956. e16, 2022
512022
TRPML1 promotes protein homeostasis in melanoma cells by negatively regulating MAPK and mTORC1 signaling
SY Kasitinon, U Eskiocak, M Martin, D Bezwada, V Khivansara, ...
Cell reports 28 (9), 2293-2305. e9, 2019
472019
Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs
FW Foss Jr, TP Mathews, Y Kharel, PC Kennedy, AH Snyder, MD Davis, ...
Bioorganic & medicinal chemistry 17 (16), 6123-6136, 2009
462009
Stable isotope tracing to assess tumor metabolism in vivo
B Faubert, A Tasdogan, SJ Morrison, TP Mathews, RJ DeBerardinis
Nature protocols 16 (11), 5123-5145, 2021
442021
Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells
AB Aurora, V Khivansara, A Leach, JG Gill, M Martin-Sandoval, C Yang, ...
Proceedings of the National Academy of Sciences 119 (6), e2120617119, 2022
402022
Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration
L Qi, MS Martin-Sandoval, S Merchant, W Gu, M Eckhardt, TP Mathews, ...
Cell Stem Cell 28 (11), 1982-1999. e8, 2021
402021
The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage
S Jun, S Mahesula, TP Mathews, MS Martin-Sandoval, Z Zhao, ...
Cell metabolism 33 (9), 1777-1792. e8, 2021
402021
Chemical modulation of glycerolipid signaling and metabolic pathways
SA Scott, TP Mathews, PT Ivanova, CW Lindsley, HA Brown
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014
402014
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Articles 1–20