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Alan Huett
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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
JD Rioux, RJ Xavier, KD Taylor, MS Silverberg, P Goyette, A Huett, ...
Nature genetics 39 (5), 596-604, 2007
21402007
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
SA McCarroll, A Huett, P Kuballa, SD Chilewski, A Landry, P Goyette, ...
Nature genetics 40 (9), 1107-1112, 2008
8442008
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
P Kuballa, A Huett, JD Rioux, MJ Daly, RJ Xavier
PloS one 3 (10), e3391, 2008
4302008
Crohn's disease‐associated adherent‐invasive E. coli are selectively favoured by impaired autophagy to replicate intracellularly
P Lapaquette, AL Glasser, A Huett, RJ Xavier, A Darfeuille‐Michaud
Cellular microbiology 12 (1), 99-113, 2010
3902010
Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium
S Wiles, S Clare, J Harker, A Huett, D Young, G Dougan, G Frankel
Cellular microbiology 6 (10), 963-972, 2004
2702004
The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular Salmonella Typhimurium
A Huett, RJ Heath, J Begun, SO Sassi, LA Baxt, JM Vyas, MB Goldberg, ...
Cell host & microbe 12 (6), 778-790, 2012
2332012
Human leucine-rich repeat proteins: a genome-wide bioinformatic categorization and functional analysis in innate immunity
ACY Ng, JM Eisenberg, RJW Heath, A Huett, CM Robinson, GJ Nau, ...
Proceedings of the National Academy of Sciences 108 (supplement_1), 4631-4638, 2011
2092011
Crohn disease: a current perspective on genetics, autophagy and immunity
TS Stappenbeck, JD Rioux, A Mizoguchi, T Saitoh, A Huett, ...
Autophagy 7 (4), 355-374, 2011
1442011
Autophagy as an important process in gut homeostasis and Crohn’s disease pathogenesis
RJ Xavier, A Huett, JD Rioux
Gut 57 (6), 717-720, 2008
912008
Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice
CKF Li, SLF Pender, KM Pickard, V Chance, JA Holloway, A Huett, ...
The Journal of Immunology 173 (8), 5171-5179, 2004
882004
Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria …
F Bowe, EC Lavelle, EA McNeela, C Hale, S Clare, B Arico, MM Giuliani, ...
Infection and immunity 72 (7), 4052-4060, 2004
762004
A systems biology viewpoint on autophagy in health and disease
A Huett, G Goel, RJ Xavier
Current opinion in gastroenterology 26 (4), 302-309, 2010
632010
A novel hybrid yeast-human network analysis reveals an essential role for FNBP1L in antibacterial autophagy
A Huett, A Ng, Z Cao, P Kuballa, M Komatsu, MJ Daly, DK Podolsky, ...
The Journal of Immunology 182 (8), 4917-4930, 2009
562009
Tribbles 2 (Trib2) is a novel regulator of toll-like receptor 5 signaling
SC Wei, IM Rosenberg, Z Cao, AS Huett, RJ Xavier, DK Podolsky
Inflammatory bowel diseases 18 (5), 877-888, 2012
522012
DLGH1 is a negative regulator of T-lymphocyte proliferation
LM Stephenson, B Sammut, DB Graham, J Chan-Wang, KL Brim, ...
Molecular and cellular biology 27 (21), 7574-7581, 2007
492007
Autophagy at the gut interface: mucosal responses to stress and the consequences for inflammatory bowel diseases
A Huett, RJ Xavier
Inflammatory bowel diseases 16 (1), 152-174, 2010
352010
DLG1 is an anchor for the E3 ligase MARCH2 at sites of cell–cell contact
Z Cao, A Huett, P Kuballa, C Giallourakis, RJ Xavier
Cellular signalling 20 (1), 73-82, 2008
352008
Vaccines against human enteric bacterial pathogens
G Dougan, A Huett, S Clare
British medical bulletin 62 (1), 113-123, 2002
352002
Picosecond ultrasonics for elasticity-based imaging and characterization of biological cells
F Pérez-Cota, R Fuentes-Domínguez, S La Cavera, W Hardiman, M Yao, ...
Journal of Applied Physics 128 (16), 2020
292020
The cytoskeletal scaffold Shank3 is recruited to pathogen-induced actin rearrangements
A Huett, JM Leong, DK Podolsky, RJ Xavier
Experimental cell research 315 (12), 2001-2011, 2009
212009
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Articles 1–20