| Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia C Kim, DH Ho, JE Suk, S You, S Michael, J Kang, S Joong Lee, E Masliah, ... Nat Communications 4, 1562, 2013 | 794 | 2013 |
| A compendium of promoter-centered long-range chromatin interactions in the human genome I Jung, A Schmitt, Y Diao, AJ Lee, T Liu, D Yang, C Tan, J Eom, M Chan, ... Nature genetics 51 (10), 1442-1449, 2019 | 289 | 2019 |
| Alpha-synuclein stimulation of astrocytes: potential role for neuroinflammation and neuroprotection HJ Lee, C Kim, SJ Lee Oxidative medicine and cellular longevity 3 (4), 283-287, 2010 | 159 | 2010 |
| Exposure to bacterial endotoxin generates a distinct strain of α-synuclein fibril C Kim, G Lv, JS Lee, BC Jung, M Masuda-Suzukake, CS Hong, E Valera, ... Scientific reports 6 (1), 30891, 2016 | 146 | 2016 |
| LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation EJ Bae, DK Kim, C Kim, M Mante, A Adame, E Rockenstein, A Ulusoy, ... Nature communications 9 (1), 3465, 2018 | 145 | 2018 |
| Antagonizing Neuronal Toll-like Receptor 2 Prevents Synucleinopathy by Activating Autophagy Kim, C., Rockenstein, E., Spencer, B., Kim, H.K., Adame, A., Trejo, M ... Cell reports 13, 771-782, 2015 | 134 | 2015 |
| Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation C Kim, B Spencer, E Rockenstein, H Yamakado, M Mante, A Adame, ... Molecular neurodegeneration 13 (1), 43, 2018 | 133 | 2018 |
| Controlling the mass action of α‐synuclein in Parkinson’s disease C Kim, SJ Lee Journal of neurochemistry 107 (2), 303-316, 2008 | 128 | 2008 |
| HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders Fields, J.A., Serger, E., Campos, S., Divakaruni, A.S., Kim, C., Smith, K ... Neurobiology of disease 86, 154, 2016 | 96 | 2016 |
| Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2 C Kim, HJ Lee, E Masliah, SJ Lee Experimental neurobiology 25 (3), 113, 2016 | 91 | 2016 |
| Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy O El-Agnaf, C Overk, E Rockenstein, M Mante, J Florio, A Adame, ... Neurobiology of disease 104, 85-96, 2017 | 87 | 2017 |
| Apigenin-induced apoptosis is mediated by reactive oxygen species and activation of ERK1/2 in rheumatoid fibroblast-like synoviocytes GC Shin, C Kim, JM Lee, WS Cho, SG Lee, M Jeong, J Cho, K Lee Chemico-biological interactions 182 (1), 29-36, 2009 | 77 | 2009 |
| β1-integrin-dependent migration of microglia in response to neuron-released α-synuclein C Kim, ED Cho, HK Kim, S You, HJ Lee, D Hwang, SJ Lee Experimental & molecular medicine 46 (4), e91-e91, 2014 | 70 | 2014 |
| Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models M Iba, C Kim, M Sallin, S Kwon, A Verma, C Overk, RA Rissman, R Sen, ... Journal of Neuroinflammation 17, 1-14, 2020 | 62 | 2020 |
| LRRK2 mediates microglial neurotoxicity via NFATc2 in rodent models of synucleinopathies C Kim, A Beilina, N Smith, Y Li, M Kim, R Kumaran, A Kaganovich, ... Science translational medicine 12 (565), eaay0399, 2020 | 60 | 2020 |
| A new synthetic chalcone derivative, 2-hydroxy-3', 5, 5'-trimethoxychalcone (DK-139), suppresses the Toll-like receptor 4-mediated inflammatory response through inhibition of … YH Lee, SH Jeon, SH Kim, C Kim, SJ Lee, D Koh, Y Lim, K Ha, SY Shin Experimental & molecular medicine 44 (6), 369-377, 2012 | 60 | 2012 |
| alpha-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy Body disease. Spencer, B., Kim, C., Gonzalez, T., Bisquertt, A., Patrick, C., Rockenstein ... Human molecular genetics 25 (6), 1100, 2016 | 59 | 2016 |
| Glucocerebrosidase Modulates Cognitive and Motor Activities in Murine Models of Parkinson's Disease SSP Rockenstein E., Clarke J., Viel C., Panarello N., Treleaven C.M., Kim C ... Human molecular genetics 25 (13), 2645, 2016 | 52 | 2016 |
| Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ... PLoS biology 19 (12), e3001480, 2021 | 51 | 2021 |
| Immunotherapies for aging-related neurodegenerative diseases—emerging perspectives and new targets S Kwon, M Iba, C Kim, E Masliah Neurotherapeutics 17 (3), 935-954, 2020 | 50 | 2020 |
Seung-Jae LeeProfessor of Biomedical Sciences, Seoul National UniversityVerified email at snu.ac.kr
