Gerard R  Dawson
Gerard R Dawson
P1vital LTD
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Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype
RM McKernan, TW Rosahl, DS Reynolds, C Sur, KA Wafford, JR Atack, ...
Nature neuroscience 3 (6), 587-592, 2000
β-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity
H Zheng, M Jiang, ME Trumbauer, DJS Sirinathsinghji, R Hopkins, ...
Cell 81 (4), 525-531, 1995
Enhanced learning and memory and altered GABAergic synaptic transmission in mice lacking the α5 subunit of the GABAAReceptor
N Collinson, FM Kuenzi, W Jarolimek, KA Maubach, R Cothliff, C Sur, ...
Journal of Neuroscience 22 (13), 5572-5580, 2002
Use of the elevated plus maze in the search for novel anxiolytic agents
GR Dawson, MD Tricklebank
Trends in pharmacological sciences 16 (2), 33-36, 1995
Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the β-amyloid precursor protein
GR Dawson, GR Seabrook, H Zheng, DW Smith, S Graham, G O'dowd, ...
Neuroscience 90 (1), 1-13, 1999
Sedation and anesthesia mediated by distinct GABAA receptor isoforms
DS Reynolds, TW Rosahl, J Cirone, GF O'Meara, A Haythornthwaite, ...
Journal of Neuroscience 23 (24), 8608-8617, 2003
Mechanisms contributing to the deficits in hippocampal synaptic plasticity in mice lacking amyloid precursor protein
GR Seabrook, DW Smith, BJ Bowery, A Easter, T Reynolds, SM Fitzjohn, ...
Neuropharmacology 38 (3), 349-359, 1999
A demonstration of observational learning in rats using a bidirectional control
CM Heyes, GR Dawson
The Quarterly Journal of Experimental Psychology Section B 42 (1b), 59-71, 1990
Evidence for a significant role of α3-containing GABAA receptors in mediating the anxiolytic effects of benzodiazepines
R Dias, WFA Sheppard, RL Fradley, EM Garrett, JL Stanley, SJ Tye, ...
Journal of Neuroscience 25 (46), 10682-10688, 2005
An inverse agonist selective for α5 subunit-containing GABAA receptors enhances cognition
GR Dawson, KA Maubach, N Collinson, M Cobain, BJ Everitt, ...
Journal of Pharmacology and Experimental Therapeutics 316 (3), 1335-1345, 2006
Loss of the major GABAA receptor subtype in the brain is not lethal in mice
C Sur, KA Wafford, DS Reynolds, KL Hadingham, F Bromidge, ...
Journal of Neuroscience 21 (10), 3409-3418, 2001
Different GABAA receptor subtypes mediate the anxiolytic, abuse-related, and motor effects of benzodiazepine-like drugs in primates
JK Rowlett, DM Platt, S Lelas, JR Atack, GR Dawson
Proceedings of the National Academy of Sciences 102 (3), 915-920, 2005
The mouse beam walking assay offers improved sensitivity over the mouse rotarod in determining motor coordination deficits induced by benzodiazepines
JL Stanley, RJ Lincoln, TA Brown, LM McDonald, GR Dawson, ...
Journal of Psychopharmacology 19 (3), 221-227, 2005
TPA023 [7-(1, 1-dimethylethyl)-6-(2-ethyl-2H-1, 2, 4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1, 2, 4-triazolo [4, 3-b] pyridazine], an agonist selective for α2-and α3 …
JR Atack, KA Wafford, SJ Tye, SM Cook, B Sohal, A Pike, C Sur, D Melillo, ...
Journal of Pharmacology and Experimental Therapeutics 316 (1), 410-422, 2006
L-655,708 enhances cognition in rats but is not proconvulsant at a dose selective for α5-containing GABAA receptors
JR Atack, PJ Bayley, GR Seabrook, KA Wafford, RM McKernan, ...
Neuropharmacology 51 (6), 1023-1029, 2006
Identification of a novel, selective GABAA α5 receptor inverse agonist which enhances cognition
MS Chambers, JR Atack, HB Broughton, N Collinson, S Cook, ...
Journal of medicinal chemistry 46 (11), 2227-2240, 2003
Imitation in rats: Initial responding and transfer evidence
CM Heyes, GR Dawson, T Nokes
The Quarterly Journal of Experimental Psychology 45 (3), 229-240, 1992
3-Phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and Analogues:  High-Affinity γ-Aminobutyric Acid-A Benzodiazepine Receptor Ligands with α2 …
RW Carling, KW Moore, LJ Street, D Wild, C Isted, PD Leeson, S Thomas, ...
Journal of Medicinal Chemistry 47 (7), 1807-1822, 2004
A quantitative trait locus influencing anxiety in the laboratory rat
A Fernández-Teruel, RM Escorihuela, JA Gray, R Aguilar, L Gil, ...
Genome Research 12 (4), 618-626, 2002
Anxiogenic properties of an inverse agonist selective for α3 subunit‐containing GABAA receptors
JR Atack, PH Hutson, N Collinson, G Marshall, G Bentley, C Moyes, ...
British journal of pharmacology 144 (3), 357-366, 2005
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