| VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model M Azzouz, GS Ralph, E Storkebaum, LE Walmsley, KA Mitrophanous, ... Nature 429 (6990), 413-417, 2004 | 793 | 2004 |
| Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model GS Ralph, PA Radcliffe, DM Day, JM Carthy, MA Leroux, DCP Lee, ... Nature medicine 11 (4), 429-433, 2005 | 653 | 2005 |
| Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery ND Mazarakis, M Azzouz, JB Rohll, FM Ellard, FJ Wilkes, AL Olsen, ... Human molecular genetics 10 (19), 2109-2121, 2001 | 506 | 2001 |
| Systemic delivery of scAAV9 expressing SMN prolongs survival in a model of spinal muscular atrophy CF Valori, K Ning, M Wyles, RJ Mead, AJ Grierson, PJ Shaw, M Azzouz Science translational medicine 2 (35), 35ra42-35ra42, 2010 | 330 | 2010 |
| Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained … M Azzouz, E Martin-Rendon, RD Barber, KA Mitrophanous, EE Carter, ... Journal of Neuroscience 22 (23), 10302-10312, 2002 | 298 | 2002 |
| Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy M Azzouz, T Le, GS Ralph, L Walmsley, UR Monani, DCP Lee, F Wilkes, ... The Journal of clinical investigation 114 (12), 1726-1731, 2004 | 259 | 2004 |
| Dopamine gene therapy for Parkinson’s disease in a nonhuman primate without associated dyskinesia B Jarraya, S Boulet, G Scott Ralph, C Jan, G Bonvento, M Azzouz, ... Science translational medicine 1 (2), 2ra4-2ra4, 2009 | 226 | 2009 |
| Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus AF Hottinger, M Azzouz, N Deglon, P Aebischer, AD Zurn Journal of Neuroscience 20 (15), 5587-5593, 2000 | 216 | 2000 |
| C9orf72 expansion disrupts ATM-mediated chromosomal break repair C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ... Nature neuroscience 20 (9), 1225-1235, 2017 | 185 | 2017 |
| Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2 M Azzouz, A Hottinger, JC Paterna, AD Zurn, P Aebischer, H Büeler Human molecular genetics 9 (5), 803-811, 2000 | 180 | 2000 |
| Transduction patterns of pseudotyped lentiviral vectors in the nervous system LF Wong, M Azzouz, LE Walmsley, Z Askham, FJ Wilkes, ... Molecular Therapy 9 (1), 101-111, 2004 | 169 | 2004 |
| LRP-1-mediated intracellular antibody delivery to the Central Nervous System X Tian, S Nyberg, PS Sharp, J Madsen, N Daneshpour, SP Armes, ... Scientific reports 5 (1), 11990, 2015 | 160 | 2015 |
| PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons K Ning, C Drepper, CF Valori, M Ahsan, M Wyles, A Higginbottom, ... Human molecular genetics 19 (16), 3159-3168, 2010 | 157 | 2010 |
| Retinoic acid receptor β2 promotes functional regeneration of sensory axons in the spinal cord LF Wong, PK Yip, A Battaglia, J Grist, J Corcoran, M Maden, M Azzouz, ... Nature neuroscience 9 (2), 243-250, 2006 | 154 | 2006 |
| SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits GM Hautbergue, LM Castelli, L Ferraiuolo, A Sanchez-Martinez, ... Nature communications 8 (1), 16063, 2017 | 140 | 2017 |
| Progressive motor neuron impairment in an animal model of familial amyotrophic lateral sclerosis M Azzouz, N Leclerc, M Gurney, JM Warter, P Poindron, J Borg Muscle & Nerve: Official Journal of the American Association of …, 1997 | 133 | 1997 |
| Encapsulation of biomacromolecules within polymersomes by electroporation L Wang, L Chierico, D Little, N Patikarnmonthon, Z Yang, M Azzouz, ... Angewandte Chemie 124 (44), 11284-11287, 2012 | 130 | 2012 |
| Optimised and Rapid Pre-clinical Screening in the SOD1G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis (ALS) RJ Mead, EJ Bennett, AJ Kennerley, P Sharp, C Sunyach, P Kasher, ... PloS one 6 (8), e23244, 2011 | 109 | 2011 |
| Lentivector‐mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model E Dowd, C Monville, EM Torres, LF Wong, M Azzouz, ND Mazarakis, ... European Journal of Neuroscience 22 (10), 2587-2595, 2005 | 109 | 2005 |
| Lentiviral vectors for treating and modeling human CNS disorders M Azzouz, SM Kingsman, ND Mazarakis The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004 | 99 | 2004 |
Pamela J ShawProfessor of Neurology, University of SheffieldVerified email at sheffield.ac.uk
