| Biological mechanisms linking obesity and cancer risk: new perspectives DL Roberts, C Dive, AG Renehan Annual review of medicine 61, 301-316, 2010 | 743 | 2010 |
| Obesity and cancer: pathophysiological and biological mechanisms AG Renehan, DL Roberts, C Dive Archives of physiology and biochemistry 114 (1), 71-83, 2008 | 511 | 2008 |
| Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition IS Goping, M Barry, P Liston, T Sawchuk, G Constantinescu, KM Michalak, ... Immunity 18 (3), 355-365, 2003 | 289 | 2003 |
| The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity DL Roberts, W Merrison, M MacFarlane, GM Cohen The Journal of cell biology 153 (1), 221-228, 2001 | 149 | 2001 |
| Development and validation of a 28-gene hypoxia-related prognostic signature for localized prostate Cancer L Yang, D Roberts, M Takhar, N Erho, BAS Bibby, N Thiruthaneeswaran, ... EBioMedicine 31, 182-189, 2018 | 137 | 2018 |
| Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death DA Tennant, C Frezza, ED MacKenzie, QD Nguyen, L Zheng, MA Selak, ... Oncogene 28 (45), 4009-4021, 2009 | 135 | 2009 |
| Sarcopenia in cancer: Risking more than muscle loss M Anjanappa, M Corden, A Green, D Roberts, P Hoskin, A McWilliam, ... Technical Innovations & Patient Support in Radiation Oncology 16, 50-57, 2020 | 100 | 2020 |
| Distinct patterns of infiltrating CD8+ T cells in HPV+ and CD68 macrophages in HPV-oropharyngeal squamous cell carcinomas are associated with better clinical outcome but PD-L1 … K Oguejiofor, H Galletta-Williams, SJ Dovedi, DL Roberts, PL Stern, ... Oncotarget 8 (9), 14416, 2017 | 94 | 2017 |
| Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma IV Linnik, MLJ Scott, KF Holliday, N Woodhouse, JC Waterton, ... Magnetic Resonance in Medicine 71 (5), 1854-1862, 2014 | 75 | 2014 |
| Contribution of HIF-1 and drug penetrance to oxaliplatin resistance in hypoxic colorectal cancer cells DL Roberts, KJ Williams, RL Cowen, M Barathova, AJ Eustace, ... British journal of cancer 101 (8), 1290-1297, 2009 | 69 | 2009 |
| Hypoxic human cancer cells are sensitized to BH-3 mimetic–induced apoptosis via downregulation of the Bcl-2 protein Mcl-1 LRE Harrison, D Micha, M Brandenburg, KL Simpson, CJ Morrow, ... The Journal of Clinical Investigation 121 (3), 1075, 2011 | 65 | 2011 |
| Caspase-3 cleaves Apaf-1 into an approximately 30 kDa fragment that associates with an inappropriately oligomerized and biologically inactive approximately 1.4 MDa apoptosome … SB Bratton, G Walker, DL Roberts, K Cain, GM Cohen Cell death and differentiation 8 (4), 425-433, 2001 | 64* | 2001 |
| A preliminary study of the activation of endogenous pancreatic exocrine enzymes during automated porcine islet isolation. SA White, H Djaballah, DP Hughes, DL Roberts, HH Contractor, S Pathak, ... Cell transplantation 8 (3), 265-276, 1998 | 43 | 1998 |
| Global gene expression in pseudomyxoma peritonei, with parallel development of two immortalized cell lines DL Roberts, ST O'Dwyer, PL Stern, AG Renehan Oncotarget 6 (13), 10786, 2015 | 36 | 2015 |
| The hypoxia marker CAIX is prognostic in the UK phase III VorteX-Biobank cohort: an important resource for translational research in soft tissue sarcoma L Forker, P Gaunt, S Sioletic, P Shenjere, R Potter, D Roberts, J Irlam, ... British journal of cancer 118 (5), 698-704, 2018 | 22 | 2018 |
| Mitochondria at the heart of the cytotoxic attack DL Roberts, IS Goping, RC Bleackley Biochemical and biophysical research communications 304 (3), 513-518, 2003 | 22 | 2003 |
| A framework for the in vitro evaluation of cancer-relevant molecular characteristics and mitogenic potency of insulin analogues I Baricevic, DR Jones, DL Roberts, A Lutzen, A Lundby, J Worm, ... Carcinogenesis 36 (9), 1040-1050, 2015 | 19 | 2015 |
| Chronic Insulin Exposure does not Cause Insulin Resistance but is Associated with Chemo-resistance in Colon Cancer Cells I Baricevic, DL Roberts, AG Renehan Hormone and Metabolic Research 46 (02), 85-93, 2014 | 18 | 2014 |
| Effect of prolonged formalin fixation on immunohistochemical staining for the proliferation marker Ki67 E Hitchman, C Hodgkinson, D Roberts, G Ashton, Z Yunus, R Byers, ... Histopathology 59 (6), 1261-1263, 2011 | 15 | 2011 |
| Reciprocal relationship between expression of hypoxia inducible factor 1α (HIF-1α) and the pro-apoptotic protein Bid in ex vivo colorectal cancer MM Seenath, D Roberts, C Cawthorne, MP Saunders, GR Armstrong, ... British journal of cancer 99 (3), 459-463, 2008 | 14 | 2008 |
