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Isaac Dean
Isaac Dean
Postdoctoral Training Fellow, Institute of Cancer Research
Verified email at icr.ac.uk
Title
Cited by
Cited by
Year
In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue
Z Li, ZK Tuong, I Dean, C Willis, F Gaspal, R Fiancette, S Idris, B Kennedy, ...
Journal of Experimental Medicine 219 (6), e20210749, 2022
602022
Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression
JW Opzoomer, JE Anstee, I Dean, EJ Hill, I Bouybayoune, J Caron, ...
Science advances 7 (45), eabg9518, 2021
342021
LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer
JE Anstee, KT Feehan, JW Opzoomer, I Dean, HP Muller, M Bahri, ...
Developmental Cell 58 (17), 1548-1561. e10, 2023
82023
Migration of stem-like CD8 T cells between tissue microenvironments underpins successful anti-tumour immune responses
BC Kennedy, I Dean, DR Withers
Discovery Immunology 2 (1), kyad004, 2023
62023
Rapid functional impairment of natural killer cells following tumor entry limits anti-tumor immunity
I Dean, CYC Lee, ZK Tuong, Z Li, CA Tibbitt, C Willis, F Gaspal, ...
Nature Communications 15 (1), 683, 2024
32024
Tspan6 stimulates the chemoattractive potential of breast cancer cells for B cells in an EV-and LXR-dependent manner
G Molostvov, M Gachechiladze, AM Shaaban, S Hayward, I Dean, ...
Cell reports 42 (3), 2023
32023
Rapid establishment of a tumor-retained state curtails the contribution of conventional NK cells to anti-tumor immunity in solid cancers
IW Dean, CYC Lee, ZK Tuong, Z Li, CA Tibbitt, C Willis, F Gaspal, ...
bioRxiv, 2023.08. 10.552797, 2023
32023
Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer
JE Anstee, JW Opzoomer, I Dean, HP Muller, M Bahri, K Liakath-Ali, Z Liu, ...
bioRxiv, 2022.02. 03.478952, 2022
22022
Tumour-retained activated CCR7+ dendritic cells are heterogeneous and regulate local anti-tumour cytolytic activity
CYC Lee, BC Kennedy, N Richoz, I Dean, ZK Tuong, F Gaspal, Z Li, ...
Nature Communications 15 (1), 682, 2024
12024
Protocol for transcutaneous tumor photolabeling to track immune cells in vivo using Kaede mice
I Dean, BC Kennedy, Z Li, F Berditchevski, DR Withers
STAR protocols 5 (2), 102956, 2024
2024
Time-, tissue-and treatment-associated heterogeneity in tumour-residing migratory DCs
CYC Lee, BC Kennedy, N Richoz, I Dean, ZK Tuong, F Gaspal, Z Li, ...
bioRxiv, 2023.07. 03.547454, 2023
2023
Lyve-1 expressing macrophages direct the expansion of pericytes within the perivascular niche to support angiogenesis in cancer
JW Opzoomer, JE Anstee, I Dean, EJ Hill, I Bouybayoune, J Caron, ...
Cancer Research 81 (13_Supplement), 113-113, 2021
2021
King’s Research Portal
JW Opzoomer, JE Anstee, I Dean, EJ Hill, I Bouybayoune, J Caron, ...
Lyve-1 expressing perivascular macrophages orchestrate pericyte expansion to sustain angiogenesis in cancer
JW Opzoomer, JE Anstee, I Dean, EJ Hill, I Bouybayoune, J Caron, ...
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