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Olwyn R. Mahon
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Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner
OR Mahon, DC Browe, T Gonzalez-Fernandez, P Pitacco, IT Whelan, ...
Biomaterials 239, 119833, 2020
2532020
Tissue-specific extracellular matrix scaffolds for the regeneration of spatially complex musculoskeletal tissues
GM Cunniffe, PJ Díaz-Payno, EJ Sheehy, SE Critchley, HV Almeida, ...
Biomaterials 188, 63-73, 2019
1062019
Osteoarthritis-associated basic calcium phosphate crystals alter immune cell metabolism and promote M1 macrophage polarization
OR Mahon, DJ Kelly, GM McCarthy, A Dunne
Osteoarthritis and Cartilage 28 (5), 603-612, 2020
622020
Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages
LC Shanley, OR Mahon, DJ Kelly, A Dunne
Acta Biomaterialia 133, 208-221, 2021
562021
Growth plate extracellular matrix-derived scaffolds for large bone defect healing.
GM Cunniffe, PJ Díaz-Payno, JS Ramey, OR Mahon, A Dunne, ...
Royal College of Surgeons in Ireland, 2017
492017
Orthopaedic implant materials drive M1 macrophage polarization in a spleen tyrosine kinase-and mitogen-activated protein kinase-dependent manner
OR Mahon, S O'Hanlon, CC Cunningham, GM McCarthy, C Hobbs, ...
Acta biomaterialia 65, 426-435, 2018
412018
Glyoxal cross‐linking of solubilized extracellular matrix to produce highly porous, elastic, and chondro‐permissive scaffolds for orthopedic tissue engineering
DC Browe, OR Mahon, PJ Díaz‐Payno, N Cassidy, I Dudurych, A Dunne, ...
Journal of Biomedical Materials Research Part A 107 (10), 2222-2234, 2019
352019
Disease-associated particulates and joint inflammation; mechanistic insights and potential therapeutic targets
OR Mahon, A Dunne
Frontiers in Immunology 9, 380087, 2018
232018
S100A8 acts as an autocrine priming signal for heme-induced human pro-inflammatory responses in hemolytic inflammation
AAA Silveira, OR Mahon, CC Cunningham, EM Corr, R Mendonça, ...
Journal of leukocyte biology 106 (1), 35-43, 2019
122019
Extracellular matrix scaffolds derived from different musculoskeletal tissues drive distinct macrophage phenotypes and direct tissue-specific cellular differentiation
OR Mahon, DC Browe, PJ Diaz-Payno, P Pitacco, KT Cunningham, ...
Journal of Immunology and Regenerative Medicine 12, 100041, 2021
112021
A spheroid model of early and late‐stage osteosarcoma mimicking the divergent relationship between tumor elimination and bone regeneration
FE Freeman, R Burdis, OR Mahon, DJ Kelly, N Artzi
Advanced Healthcare Materials 11 (7), 2101296, 2022
102022
Localized Nanoparticle‐Mediated Delivery of miR‐29b Normalizes the Dysregulation of Bone Homeostasis Caused by Osteosarcoma whilst Simultaneously Inhibiting Tumor Growth
FE Freeman, P Dosta, LC Shanley, N Ramirez Tamez, CJ Riojas Javelly, ...
Advanced Materials 35 (23), 2207877, 2023
92023
Extracellular vesicle functionalized melt electrowritten scaffolds for bone tissue engineering
KF Eichholz, A Federici, M Riffault, I Woods, OR Mahon, L O’Driscoll, ...
Advanced NanoBiomed Research 1 (10), 2100037, 2021
82021
Macrophage metabolic profile is altered by hydroxyapatite particle size
LC Shanley, OR Mahon, SA O'Rourke, NGB Neto, MG Monaghan, ...
Acta Biomaterialia 160, 311-321, 2023
62023
Generating an M2 pro‐regenerative macrophage phenotype using nanoHA particles for bone tissue engineering
O Mahon
European Cells and Materials 33, 2017
12017
Characterisation of Chronic Lymphocytic Leukaemia (CLL) immune profiles using single cell multi-omics
OR Mahon, C King, E Fennell, SE Hickey, PA Kiely, R Clifford, K McGourty
EUROPEAN JOURNAL OF IMMUNOLOGY 52, 70-70, 2022
2022
EXTRACELLULAR MATRIX SCAFFOLDS DERIVED FROM DIFFERENT MUSCULOSKELETAL TISSUES DRIVE DISTINCT MACROPHAGE PHENOTYPES AND DIRECT TISSUE-SPECIFIC CELLULAR DIFFERENTIATION
OR Mahon, DC Browe, P Pitacco, P Diaz-Payno, A Dunne, DJ Kelly
TISSUE ENGINEERING PART A 28, S540-S540, 2022
2022
Mechanically Activated Extracellular Vesicle Functionalised Melt Electrowritten Materials for Bone Regeneration: A Mechano-Biomimetic Scaffold
KF Eichholz, A Federici, M Riffault, I Woods, OR Mahon, L O’Driscoll, ...
bioRxiv, 2021.03. 29.437528, 2021
2021
Characterisation of the immune response to calcium phosphate particulates; implications for osteoarthritis and bone tissue engineering
O Mahon
Trinity College Dublin, 2020
2020
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Articles 1–19