Roberto Di Santo
Roberto Di Santo
Professore di Chimica Farmaceutica, Sapienza Universitą di Roma
Verified email at uniroma1.it
TitleCited byYear
Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling
M Artico, R Di Santo, R Costi, E Novellino, G Greco, S Massa, ...
Journal of medicinal chemistry 41 (21), 3948-3960, 1998
2031998
Heck reaction on anthraquinone derivatives: ligand, solvent and salt effects
W Cabri, I Candiani, S DeBernardinis, F Francalanci, S Penco, R Santo
The Journal of Organic Chemistry 56 (20), 5796-5800, 1991
1911991
Antimycobacterial pyrroles: synthesis, anti-Mycobacterium tuberculosis activity and QSAR studies
R Ragno, GR Marshall, R Di Santo, R Costi, S Massa, R Rompei, M Artico
Bioorganic & medicinal chemistry 8 (6), 1423-1432, 2000
1522000
6-[1-(4-Fluorophenyl) methyl-1H-pyrrol-2-yl)]-2, 4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in …
E Tramontano, F Esposito, R Badas, R Di Santo, R Costi, P La Colla
Antiviral research 65 (2), 117-124, 2005
1222005
Novel bifunctional quinolonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, biological activities, and mechanism of action
R Di Santo, R Costi, A Roux, M Artico, A Lavecchia, L Marinelli, ...
Journal of medicinal chemistry 49 (6), 1939-1945, 2006
1042006
Antifungal Agents. 10. New Derivatives of 1-[(Aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, Synthesis, Anti-Candida Activity, and Quantitative Structure …
A Tafi, R Costi, M Botta, R Di Santo, F Corelli, S Massa, A Ciacci, ...
Journal of medicinal chemistry 45 (13), 2720-2732, 2002
922002
2, 6-Bis (3, 4, 5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays
R Costi, R Di Santo, M Artico, S Massa, R Ragno, R Loddo, M La Colla, ...
Bioorganic & medicinal chemistry 12 (1), 199-215, 2004
912004
Antifungal Agents. 11. N-Substituted Derivatives of 1-[(Aryl)(4-aryl-1H-pyrrol-3-yl)methyl]-1H-imidazole:  Synthesis, Anti-Candida Activity, and QSAR Studies
R Di Santo, A Tafi, R Costi, M Botta, M Artico, F Corelli, M Forte, ...
Journal of medicinal chemistry 48 (16), 5140-5153, 2005
812005
Pyrrolnitrin and related pyrroles endowed with antibacterial activities against Mycobacterium tuberculosis
R Di Santo, R Costi, M Artico, S Massa, G Lampis, D Deidda, R Pompei
Bioorganic & medicinal chemistry letters 8 (20), 2931-2936, 1998
781998
Natural products as antifungal agents against clinically relevant pathogens
R Di Santo
Natural product reports 27 (7), 1084-1098, 2010
762010
Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors
R Di Santo, R Costi, M Artico, S Massa, R Ragno, GR Marshall, P La Colla
Bioorganic & medicinal chemistry 10 (8), 2511-2526, 2002
712002
Inhibiting the HIV integration process: past, present, and the future
R Di Santo
Journal of medicinal chemistry 57 (3), 539-566, 2013
682013
Novel 3, 5-bis (bromohydroxybenzylidene) piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity
D Cheng, S Valente, S Castellano, G Sbardella, R Di Santo, R Costi, ...
Journal of medicinal chemistry 54 (13), 4928-4932, 2011
662011
HIV-1 RT-associated RNase H function inhibitors: recent advances in drug development
E Tramontano, R Di Santo
Current medicinal chemistry 17 (26), 2837-2853, 2010
662010
Molecular Modeling of Azole Antifungal Agents Active against Candida albicans. 1. A Comparative Molecular Field Analysis Study
A Tafi, J Anastassopoulou, T Theophanides, M Botta, F Corelli, S Massa, ...
Journal of medicinal chemistry 39 (6), 1227-1235, 1996
641996
Cinnamoyl compounds as simple molecules that inhibit p300 histone acetyltransferase
R Costi, R Di Santo, M Artico, G Miele, P Valentini, E Novellino, ...
Journal of medicinal chemistry 50 (8), 1973-1977, 2007
582007
Novel quinolinonyl diketo acid derivatives as HIV-1 integrase inhibitors: design, synthesis, and biological activities
R Di Santo, R Costi, A Roux, G Miele, GC Crucitti, A Iacovo, F Rosi, ...
Journal of medicinal chemistry 51 (15), 4744-4750, 2008
562008
Antifungal agents. 9. 3-Aryl-4-[. alpha.-(1H-imidazol-1-yl) arylmethyl] pyrroles: A new class of potent anti-candida agents
M Artico, R Di Santo, R Costi, S Massa, A Retico, M Artico, G Apuzzo, ...
Journal of medicinal chemistry 38 (21), 4223-4233, 1995
521995
Structure–activity relationship of pyrrolyl diketo acid derivatives as dual inhibitors of HIV-1 integrase and reverse transcriptase ribonuclease H domain
G Cuzzucoli Crucitti, M Métifiot, L Pescatori, A Messore, VN Madia, ...
Journal of medicinal chemistry 58 (4), 1915-1928, 2015
492015
Probing HIV-1 integrase inhibitor binding sites with position-specific integrase-DNA cross-linking assays
AA Johnson, C Marchand, SS Patil, R Costi, R Di Santo, TR Burke, ...
Molecular pharmacology 71 (3), 893-901, 2007
492007
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