| Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression E Lapi, S Strano, G Blandino, G Bossi, C Rinaldo Oncogene: An International Journal, 304-309, 2006 | 265 | 2006 |
| Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression G Bossi, E Lapi, S Strano, C Rinaldo, G Blandino, A Sacchi Oncogene 25 (2), 304-309, 2006 | 265 | 2006 |
| MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis C Rinaldo, A Prodosmo, F Mancini, S Iacovelli, A Sacchi, F Moretti, ... Molecular cell 25 (5), 739-750, 2007 | 227 | 2007 |
| Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy M Bartucci, S Svensson, P Romania, R Dattilo, M Patrizii, M Signore, ... Cell Death & Differentiation 19 (5), 768-778, 2012 | 200 | 2012 |
| Roles for Caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development C Rinaldo, P Bazzicalupo, S Ederle, M Hilliard, A La Volpe Genetics 160 (2), 471-479, 2002 | 158 | 2002 |
| HIPK2: a multitalented partner for transcription factors in DNA damage response and development C Rinaldo, A Prodosmo, F Siepi, S Soddu Biochemistry and Cell Biology 85 (4), 411-418, 2007 | 135 | 2007 |
| Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis B Cecchinelli, L Lavra, C Rinaldo, S Iacovelli, A Gurtner, A Gasbarri, ... Molecular and cellular biology 26 (12), 4746-4757, 2006 | 131 | 2006 |
| Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis V Di Stefano, C Rinaldo, A Sacchi, S Soddu, G D'Orazi Experimental cell research 293 (2), 311-320, 2004 | 119 | 2004 |
| Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation R Amato, L D’Antona, G Porciatti, V Agosti, M Menniti, C Rinaldo, N Costa, ... Journal of molecular medicine 87 (12), 1221-1239, 2009 | 115 | 2009 |
| MDM4 (MDMX) localizes at the mitochondria and facilitates the p53‐mediated intrinsic‐apoptotic pathway F Mancini, G Di Conza, M Pellegrino, C Rinaldo, A Prodosmo, S Giglio, ... The EMBO journal 28 (13), 1926-1939, 2009 | 96 | 2009 |
| Updates on HIPK2: a resourceful oncosuppressor for clearing cancer G D’Orazi, C Rinaldo, S Soddu Journal of Experimental & Clinical Cancer Research 31, 1-8, 2012 | 88 | 2012 |
| The loss of the p53 activator HIPK2 is responsible for galectin-3 overexpression in well differentiated thyroid carcinomas L Lavra, C Rinaldo, A Ulivieri, E Luciani, P Fidanza, L Giacomelli, ... PLoS One 6 (6), e20665, 2011 | 72 | 2011 |
| HIPKs: Jack of all trades in basic nuclear activities C Rinaldo, F Siepi, A Prodosmo, S Soddu Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (11), 2124-2129, 2008 | 70 | 2008 |
| ESCRT-III is necessary for the integrity of the nuclear envelope in micronuclei but is aberrant at ruptured micronuclear envelopes generating damage J Willan, AJ Cleasby, N Flores-Rodriguez, F Stefani, C Rinaldo, ... Oncogenesis 8 (5), 29, 2019 | 64 | 2019 |
| HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody C Rinaldo, A Moncada, A Gradi, L Ciuffini, D D'Eliseo, F Siepi, ... Molecular cell 47 (1), 87-98, 2012 | 64 | 2012 |
| HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage C Lazzari, A Prodosmo, F Siepi, C Rinaldo, F Galli, M Gentileschi, ... Oncogene 30 (48), 4802-4813, 2011 | 62 | 2011 |
| HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage C Lazzari, A Prodosmo, F Siepi, C Rinaldo, F Galli, M Gentileschi, ... Oncogene 30 (48), 4802-4813, 2011 | 62 | 2011 |
| HIPK2 regulation by MDM2 determines tumor cell response to the p53-reactivating drugs nutlin-3 and RITA C Rinaldo, A Prodosmo, F Siepi, A Moncada, A Sacchi, G Selivanova, ... Cancer research 69 (15), 6241-6248, 2009 | 61 | 2009 |
| MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response M Petroni, V Veschi, A Prodosmo, C Rinaldo, I Massimi, M Carbonari, ... Molecular Cancer Research 9 (1), 67-77, 2011 | 48 | 2011 |
| HIPK2 is involved in cell proliferation and its suppression promotes growth arrest independently of DNA damage S Iacovelli, L Ciuffini, C Lazzari, G Bracaglia, C Rinaldo, A Prodosmo, ... Cell proliferation 42 (3), 373-384, 2009 | 43 | 2009 |
