Catherine Freudenreich
Catherine Freudenreich
Professor of Biology, Tufts University
Verified email at - Homepage
Cited by
Cited by
Expansion and length-dependent fragility of CTG repeats in yeast
CH Freudenreich, SM Kantrow, VA Zakian
Science 279 (5352), 853-856, 1998
Stability of a CTG/CAG trinucleotide repeat in yeast is dependent on its orientation in the genome
CH Freudenreich, JB Stavenhagen, VA Zakian
Molecular and cellular biology 17 (4), 2090-2098, 1997
An AT-rich sequence in human common fragile site FRA16D causes fork stalling and chromosome breakage in S. cerevisiae
H Zhang, CH Freudenreich
Molecular cell 27 (3), 367-379, 2007
Repeat instability during DNA repair: Insights from model systems
K Usdin, NCM House, CH Freudenreich
Critical reviews in biochemistry and molecular biology 50 (2), 142-167, 2015
Chromatin modifications and DNA repair: beyond double-strand breaks
NCM House, MR Koch, CH Freudenreich
Frontiers in genetics 5, 296, 2014
Mutations in yeast replication proteins that increase CAG/CTG expansions also increase repeat fragility
JL Callahan, KJ Andrews, VA Zakian, CH Freudenreich
Molecular and cellular biology 23 (21), 7849-7860, 2003
Trinucleotide repeat instability: a hairpin curve at the crossroads of replication, recombination, and repair
BA Lenzmeier, CH Freudenreich
Cytogenetic and genome research 100 (1-4), 7-24, 2003
Localization of an aminoacridine antitumor agent in a type II topoisomerase-DNA complex.
CH Freudenreich, KN Kreuzer
Proceedings of the National Academy of Sciences 91 (23), 11007-11011, 1994
CGG/CCG repeats exhibit orientation-dependent instability and orientation-independent fragility in Saccharomyces cerevisiae
BS Balakumaran, CH Freudenreich, VA Zakian
Human molecular genetics 9 (1), 93-100, 2000
Regulation of recombination at yeast nuclear pores controls repair and triplet repeat stability
XA Su, V Dion, SM Gasser, CH Freudenreich
Genes & development 29 (10), 1006-1017, 2015
SRS2 and SGS1 prevent chromosomal breaks and stabilize triplet repeats by restraining recombination
A Kerrest, RP Anand, R Sundararajan, R Bermejo, G Liberi, B Dujon, ...
Nature structural & molecular biology 16 (2), 159-167, 2009
Saccharomyces cerevisiae Flap Endonuclease 1 Uses Flap Equilibration To Maintain Triplet Repeat Stability
Y Liu, H Zhang, J Veeraraghavan, RA Bambara, CH Freudenreich
Molecular and cellular biology 24 (9), 4049-4064, 2004
Overcoming natural replication barriers: differential helicase requirements
RP Anand, KA Shah, H Niu, P Sung, SM Mirkin, CH Freudenreich
Nucleic acids research 40 (3), 1091-1105, 2012
Expanded CAG repeats activate the DNA damage checkpoint pathway
M Lahiri, TL Gustafson, ER Majors, CH Freudenreich
Molecular cell 15 (2), 287-293, 2004
Mutational analysis of a type II topoisomerase cleavage site: distinct requirements for enzyme and inhibitors.
CH Freudenreich, KN Kreuzer
The EMBO Journal 12 (5), 2085-2097, 1993
Chromosome fragility: molecular mechanisms and cellular consequences
CH Freudenreich
Frontiers in Bioscience-Landmark 12 (13), 4911-4924, 2007
Cytosine deamination and base excision repair cause R-loop–induced CAG repeat fragility and instability in Saccharomyces cerevisiae
XA Su, CH Freudenreich
Proceedings of the National Academy of Sciences 114 (40), E8392-E8401, 2017
Double-strand break repair pathways protect against CAG/CTG repeat expansions, contractions and repeat-mediated chromosomal fragility in Saccharomyces cerevisiae
R Sundararajan, L Gellon, RM Zunder, CH Freudenreich
Genetics 184 (1), 65-77, 2010
Structure-forming CAG/CTG repeat sequences are sensitive to breakage in the absence of Mrc1 checkpoint function and S-phase checkpoint signaling: implications for trinucleotide …
CH Freudenreich, M Lahiri
Cell Cycle 3 (11), 1370-1374, 2004
The role of fork stalling and DNA structures in causing chromosome fragility
S Kaushal, CH Freudenreich
Genes, Chromosomes and Cancer 58 (5), 270-283, 2019
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