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Michael Datto
Michael Datto
Medical Director and Associate Vice President of Clinical Laboratories, Duke University
Verified email at duke.edu - Homepage
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Year
Standards and guidelines for the interpretation and reporting of sequence variants in cancer: a joint consensus recommendation of the Association for Molecular Pathology …
MM Li, M Datto, EJ Duncavage, S Kulkarni, NI Lindeman, S Roy, ...
The Journal of molecular diagnostics 19 (1), 4-23, 2017
15512017
Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism.
MB Datto, Y Li, JF Panus, DJ Howe, Y Xiong, XF Wang
Proceedings of the National Academy of Sciences 92 (12), 5545-5549, 1995
12241995
Targeted disruption of Smad3 reveals an essential role in transforming growth factor β-mediated signal transduction
MB Datto, JP Frederick, L Pan, AJ Borton, Y Zhuang, XF Wang
Molecular and cellular biology 19 (4), 2495-2504, 1999
6071999
Functional analysis of the transforming growth factor βResponsive elements in the WAF1/Cip1/p21 promoter
MB Datto, Y Yu, XF Wang
Journal of Biological Chemistry 270 (48), 28623-28628, 1995
5561995
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
J Zhao, W Shi, YL Wang, H Chen, P Bringas Jr, MB Datto, JP Frederick, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 282 (3 …, 2002
5232002
Smads bind directly to the Jun family of AP-1 transcription factors
NT Liberati, MB Datto, JP Frederick, X Shen, C Wong, ...
Proceedings of the National Academy of Sciences 96 (9), 4844-4849, 1999
4171999
A pathway-based classification of human breast cancer
ML Gatza, JE Lucas, WT Barry, JW Kim, Q Wang, M D. Crawford, ...
Proceedings of the National Academy of Sciences 107 (15), 6994-6999, 2010
3902010
Tumor suppressor Smad4 is a transforming growth factor β-inducible DNA binding protein
JM Yingling, MB Datto, C Wong, JP Frederick, NT Liberati, XF Wang
Molecular and cellular biology 17 (12), 7019-7028, 1997
3891997
Smad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor β
C Wong, EM Rougier-Chapman, JP Frederick, MB Datto, NT Liberati, ...
Molecular and cellular biology 19 (3), 1821-1830, 1999
3471999
TGF-β–induced phosphorylation of Smad3 regulates its interaction with coactivator p300/CREB-binding protein
X Shen, PP Hu, NT Liberati, MB Datto, JP Frederick, XF Wang
Molecular biology of the cell 9 (12), 3309-3319, 1998
2771998
Extracellular matrix protein βig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation
C Ma, Y Rong, DR Radiloff, MB Datto, B Centeno, S Bao, AWM Cheng, ...
Genes & development 22 (3), 308-321, 2008
2612008
Expression of the E2F1 transcription factor overcomes type beta transforming growth factor-mediated growth suppression.
JK Schwarz, CH Bassing, I Kovesdi, MB Datto, M Blazing, S George, ...
Proceedings of the National Academy of Sciences 92 (2), 483-487, 1995
2111995
The loss of Smad3 results in a lower rate of bone formation and osteopenia through dysregulation of osteoblast differentiation and apoptosis
AJ Borton, JP Frederick, MB Datto, XF Wang, RS Weinstein
Journal of Bone and Mineral Research 16 (10), 1754-1764, 2001
2042001
Molecular mechanisms of transforming growth factor-β signaling
PP Hu, MB Datto, X Wang
Endocrine reviews 19 (3), 349-363, 1998
1971998
The viral oncoprotein E1A blocks transforming growth factor β-mediated induction of p21/WAF1/Cip1 and p15/INK4B
MB Datto, PPC Hu, TF Kowalik, J Yingling, XF Wang
Molecular and cellular biology, 1997
1781997
Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation
N Billon, D Carlisi, MB Datto, LA van Grunsven, A Watt, XF Wang, ...
Oncogene 18 (18), 2872-2882, 1999
1681999
Transforming Growth Factor-β-mediated p15INK4BInduction and Growth Inhibition in Astrocytes Is SMAD3-dependent and a Pathway Prominently Altered in Human Glioma Cell Lines
JN Rich, M Zhang, MB Datto, DD Bigner, XF Wang
Journal of Biological Chemistry 274 (49), 35053-35058, 1999
1581999
Sp1, but not Sp3, functions to mediate promoter activation by TGF-β through canonical Sp1 binding sites
JM Li, MB Datto, X Shen, PPC Hu, Y Yu, XF Wang
Nucleic acids research 26 (10), 2499-2456, 1998
1311998
Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome
WT Barry, DN Kernagis, HK Dressman, RJ Griffis, JVD Hunter, JA Olson, ...
Journal of clinical oncology 28 (13), 2198-2206, 2010
1282010
Implementation of a pooled surveillance testing program for asymptomatic SARS-CoV-2 infections on a college campus—Duke University, Durham, North Carolina, August 2–October 11 …
TN Denny
MMWR. Morbidity and mortality weekly report 69, 2020
1172020
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