Psoralens as photoactive probes of nucleic acid structure and function: organic chemistry, photochemistry, and biochemistry GD Cimino, HB Gamper, ST Isaacs, JE Hearst Annual review of biochemistry 54 (1), 1151-1193, 1985 | 922 | 1985 |
A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes HB Gamper, JE Hearst Cell 29 (1), 81-90, 1982 | 335 | 1982 |
Efficient priming of PCR with short oligonucleotides conjugated to a minor groove binder I Afonina, M Zivarts, I Kutyavin, E Lukhtanov, H Gamper, RB Meyer Nucleic acids research 25 (13), 2657-2660, 1997 | 333 | 1997 |
Action mechanism of ABC excision nuclease on a DNA substrate containing a psoralen crosslink at a defined position. B Van Houten, H Gamper, SR Holbrook, JE Hearst, A Sancar Proceedings of the National Academy of Sciences 83 (21), 8077-8081, 1986 | 243 | 1986 |
Facile preparation of nuclease resistant 3′ modified oligodeoxynucleotides HB Gamper, MW Reed, T Cox, JS Virosco, AD Adams, AA Gall, ... Nucleic acids research 21 (1), 145-150, 1993 | 194 | 1993 |
Covalently linked oligonucleotide minor grove binder conjugates IV Kutyavin, EA Lukhtanov, HB Gamper, RB Meyer Jr US Patent 5,801,155, 1998 | 192 | 1998 |
The DNA strand of chimeric RNA/DNA oligonucleotides can direct gene repair/conversion activity in mammalian and plant cell-free extracts HB Gamper, H Parekh, MC Rice, M Bruner, H Youkey, EB Kmiec Nucleic Acids Research 28 (21), 4332-4339, 2000 | 174 | 2000 |
Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract A Cole-Strauss, H Gamper, M Muñoz, N Cheng, EB Kmiec, WK Holloman Nucleic acids research 27 (5), 1323-1330, 1999 | 169 | 1999 |
Oligonucleotides containing 2-aminoadenine and 2-thiothymine act as selectively binding complementary agents IV Kutyavin, RL Rhinehart, EA Lukhtanov, VV Gorn, RB Meyer, ... Biochemistry 35 (34), 11170-11176, 1996 | 157 | 1996 |
A plausible mechanism for gene correction by chimeric oligonucleotides HB Gamper, A Cole-Strauss, R Metz, H Parekh, R Kumar, EB Kmiec Biochemistry 39 (19), 5808-5816, 2000 | 150 | 2000 |
Covalently linked oligonucleotide minor grove binder conjugates IV Kutyavin, EA Lukhtanov, HB Gamper, RB Meyer Jr US Patent 6,084,102, 2000 | 149 | 2000 |
Targeted chromosomal genomic alterations with modified single stranded oligonucleotides EB Kmiec, HB Gamper, MC Rice US Patent 6,936,467, 2005 | 146 | 2005 |
DNase I footprint of ABC excinuclease. B Van Houten, H Gamper, A Sancar, JE Hearst Journal of Biological Chemistry 262 (27), 13180-13187, 1987 | 132 | 1987 |
Efficient formation of a crosslinkable HMT monoadduct at the Kpn I recognition site H Gamper, J Piette, JE Hearst Photochemistry and photobiology 40 (1), 29-34, 1984 | 128 | 1984 |
Loss-of-function alanyl-tRNA synthetase mutations cause an autosomal-recessive early-onset epileptic encephalopathy with persistent myelination defect C Simons, LB Griffin, G Helman, G Golas, A Pizzino, M Bloom, ... The American Journal of Human Genetics 96 (4), 675-681, 2015 | 125 | 2015 |
Use of psoralen-modified oligonucleotides to trap three-stranded RecA-DNA complexes and repair of these cross-linked complexes by ABC excinuclease. S Cheng, B Van Houten, HB Gamper, A Sancar, JE Hearst Journal of Biological Chemistry 263 (29), 15110-15117, 1988 | 125 | 1988 |
Targeted chromosomal genomic alterations with modified single stranded oligonucleotides EB Kmiec, HB Gamper, MC Rice US Patent 7,226,785, 2007 | 123 | 2007 |
Interaction of T7 RNA polymerase with DNA in an elongation complex arrested at a specific psoralen adduct site. YB Shi, H Gamper, JE Hearst Journal of Biological Chemistry 263 (1), 527-534, 1988 | 122 | 1988 |
Characterization of reversible, physical binding of benzo [a] pyrene derivatives to DNA. T Meehan, H Gamper, JF Becker Journal of Biological Chemistry 257 (17), 10479-10485, 1982 | 114 | 1982 |
DNA Strand Scission by Benzo[a]pyrene Diol Epoxides HB Gamper, ASC Tung, K Straub, JC Bartholomew, M Calvin Science 197 (4304), 671-674, 1977 | 109 | 1977 |