| The structural biochemistry of the superoxide dismutases JJP Perry, DS Shin, ED Getzoff, JA Tainer Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (2), 245-262, 2010 | 650 | 2010 |
| DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities A Shibata, D Moiani, AS Arvai, J Perry, SM Harding, MM Genois, R Maity, ... Molecular cell 53 (1), 7-18, 2014 | 615 | 2014 |
| Lanosterol reverses protein aggregation in cataracts L Zhao, XJ Chen, J Zhu, YB Xi, X Yang, LD Hu, H Ouyang, SH Patel, X Jin, ... Nature 523 (7562), 607-611, 2015 | 465 | 2015 |
| SUMO‐targeted ubiquitin ligases in genome stability J Prudden, S Pebernard, G Raffa, DA Slavin, JJP Perry, JA Tainer, ... The EMBO journal 26 (18), 4089-4101, 2007 | 404 | 2007 |
| A SIM-ultaneous role for SUMO and ubiquitin JJP Perry, JA Tainer, MN Boddy Trends in biochemical sciences 33 (5), 201-208, 2008 | 271 | 2008 |
| WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing JJP Perry, SM Yannone, LG Holden, C Hitomi, A Asaithamby, S Han, ... Nature structural & molecular biology 13 (5), 414-422, 2006 | 180 | 2006 |
| Amyotrophic lateral sclerosis: update and new developments AJ Pratt, ED Getzoff, JJP Perry Degenerative neurological and neuromuscular disease, 1-14, 2012 | 133 | 2012 |
| Crystal structure of human DNA methyltransferase 1 ZM Zhang, S Liu, K Lin, Y Luo, JJ Perry, Y Wang, J Song Journal of molecular biology 427 (15), 2520-2531, 2015 | 112 | 2015 |
| Covalent inhibitors of protein–protein interactions targeting lysine, tyrosine, or histidine residues L Gambini, C Baggio, P Udompholkul, J Jossart, AF Salem, JJP Perry, ... Journal of medicinal chemistry 62 (11), 5616-5627, 2019 | 93 | 2019 |
| Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability S Pebernard, JJP Perry, JA Tainer, MN Boddy Molecular biology of the cell 19 (10), 4099-4109, 2008 | 93 | 2008 |
| Natural product anacardic acid from cashew nut shells stimulates neutrophil extracellular trap production and bactericidal activity A Hollands, R Corriden, G Gysler, S Dahesh, J Olson, SR Ali, MT Kunkel, ... Journal of Biological Chemistry 291 (27), 13964-13973, 2016 | 75 | 2016 |
| Contribution of human manganese superoxide dismutase tyrosine 34 to structure and catalysis JJP Perry, AS Hearn, DE Cabelli, HS Nick, JA Tainer, DN Silverman Biochemistry 48 (15), 3417-3424, 2009 | 71 | 2009 |
| Developing master keys to brain pathology, cancer and aging from the structural biology of proteins controlling reactive oxygen species and DNA repair JJP Perry, L Fan, JA Tainer Neuroscience 145 (4), 1280-1299, 2007 | 70 | 2007 |
| Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9. A Omanakuttan, J Nambiar, RM Harris, C Bose, N Pandurangan, ... Molecular Pharmacology, 2012 | 67 | 2012 |
| SUMO-targeted ubiquitin ligase, Rad60, and Nse2 SUMO ligase suppress spontaneous Top1–mediated DNA damage and genome instability J Heideker, J Prudden, JJP Perry, JA Tainer, MN Boddy PLoS genetics 7 (3), e1001320, 2011 | 64 | 2011 |
| PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD+ acute myeloid leukemia X He, Y Zhu, YC Lin, M Li, J Du, H Dong, J Sun, L Zhu, H Wang, Z Ding, ... Blood, The Journal of the American Society of Hematology 134 (6), 548-560, 2019 | 61 | 2019 |
| Novel peptide therapeutic approaches for cancer treatment CM Li, P Haratipour, RG Lingeman, JJP Perry, L Gu, RJ Hickey, ... Cells 10 (11), 2908, 2021 | 58 | 2021 |
| Molecular mimicry of SUMO promotes DNA repair J Prudden, JJP Perry, AS Arvai, JA Tainer, MN Boddy Nature structural & molecular biology 16 (5), 509-516, 2009 | 58 | 2009 |
| DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes J Prudden, JJP Perry, M Nie, AA Vashisht, AS Arvai, C Hitomi, G Guenther, ... Molecular and cellular biology 31 (11), 2299-2310, 2011 | 57 | 2011 |
| Structural dynamics in DNA damage signaling and repair JJP Perry, E Cotner-Gohara, T Ellenberger, JA Tainer Current opinion in structural biology 20 (3), 283-294, 2010 | 57 | 2010 |
John TainerDirector of Structural Biology, Professor at MD Anderson Cancer Center & Lawrence Berkeley LabVerified email at mdanderson.org
