| Apelin, the novel endogenous ligand of the orphan receptor APJ, regulates cardiac contractility I Szokodi, P Tavi, G Földes, S Voutilainen-Myllylä, M Ilves, H Tokola, ... Circulation research 91 (5), 434-440, 2002 | 919 | 2002 |
| GATA transcription factors in the developing and adult heart S Pikkarainen, H Tokola, R Kerkelä, H Ruskoaho Cardiovascular research 63 (2), 196-207, 2004 | 496 | 2004 |
| Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses A Clerk, TE Cullingford, SJ Fuller, A Giraldo, T Markou, S Pikkarainen, ... Journal of cellular physiology 212 (2), 311-322, 2007 | 206 | 2007 |
| GATA-4 is a nuclear mediator of mechanical stretch-activated hypertrophic program S Pikkarainen, H Tokola, T Majalahti-Palviainen, R Kerkelä, N Hautala, ... Journal of Biological Chemistry 278 (26), 23807-23816, 2003 | 152 | 2003 |
| Mechanical load-induced alterations in B-type natriuretic peptide gene expression H Tokola, N Hautala, M Marttila, J Magga, S Pikkarainen, R Kerkelä, ... Canadian journal of physiology and pharmacology 79 (8), 646-653, 2001 | 109 | 2001 |
| Distinct roles of mitogen-activated protein kinase pathways in GATA-4 transcription factor-mediated regulation of B-type natriuretic peptide gene R Kerkelä, S Pikkarainen, T Majalahti-Palviainen, H Tokola, ... Journal of Biological Chemistry 277 (16), 13752-13760, 2002 | 104 | 2002 |
| Pacing‐induced calcineurin activation controls cardiac Ca2+ signalling and gene expression P Tavi, S Pikkarainen, J Ronkainen, P Niemelä, M Ilves, M Weckström, ... The Journal of physiology 554 (2), 309-320, 2004 | 67 | 2004 |
| Unexpectedly high prevalence of common variable immunodeficiency in Finland JS Selenius, T Martelius, S Pikkarainen, S Siitonen, E Mattila, ... Frontiers in immunology 8, 1190, 2017 | 65 | 2017 |
| A high prevalence of gastrointestinal manifestations in common variable immunodeficiency S Pikkarainen, T Martelius, A Ristimäki, S Siitonen, MRJ Seppänen, ... Official journal of the American College of Gastroenterology| ACG 114 (4 …, 2019 | 62 | 2019 |
| Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility I Szokodi, R Kerkelä, AM Kubin, B Sármán, S Pikkarainen, A Kónyi, ... Circulation 118 (16), 1651-1658, 2008 | 58 | 2008 |
| Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes TE Cullingford, T Markou, SJ Fuller, A Giraldo, S Pikkarainen, ... Genome biology 9, 1-14, 2008 | 56 | 2008 |
| Endothelin-1-specific activation of B-type natriuretic peptide gene via p38 mitogen-activated protein kinase and nuclear ETS factors S Pikkarainen, H Tokola, R Kerkelä, T Majalahti-Palviainen, ... Journal of Biological Chemistry 278 (6), 3969-3975, 2003 | 53 | 2003 |
| Cardiac BNP gene activation by angiotensin II in vivo T Majalahti, M Suo-Palosaari, B Sármán, N Hautala, S Pikkarainen, ... Molecular and cellular endocrinology 273 (1-2), 59-67, 2007 | 47 | 2007 |
| Key roles of endothelin-1 and p38 MAPK in the regulation of atrial stretch response R Kerkelä, M Ilves, S Pikkarainen, H Tokola, VP Ronkainen, T Majalahti, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2011 | 44 | 2011 |
| A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3) SJ Fuller, LJ McGuffin, AK Marshall, A Giraldo, S Pikkarainen, A Clerk, ... Biochemical Journal 442 (3), 595-610, 2012 | 39 | 2012 |
| Distinct regulation of B-type natriuretic peptide transcription by p38 MAPK isoforms E Koivisto, L Kaikkonen, H Tokola, S Pikkarainen, J Aro, H Pennanen, ... Molecular and cellular endocrinology 338 (1-2), 18-27, 2011 | 35 | 2011 |
| Identification of PKCα isoform-specific effects in cardiac myocytes using antisense phosphorothioate oligonucleotides R Kerkelä, M Ilves, S Pikkarainen, H Tokola, J Ronkainen, O Vuolteenaho, ... Molecular pharmacology 62 (6), 1482-1491, 2002 | 35 | 2002 |
| Nuclear factor-κB signaling contributes to severe, but not moderate, angiotensin II-induced left ventricular remodeling B Sármán, R Skoumal, H Leskinen, J Rysä, M Ilves, Y Soini, J Tuukkanen, ... Journal of hypertension 25 (9), 1927-1939, 2007 | 34 | 2007 |
| Regulation of expression of the rat orthologue of mouse double minute 2 (MDM2) by H2O2-induced oxidative stress in neonatal rat cardiac myocytes S Pikkarainen, RA Kennedy, AK Marshall, K Lay, TA Kriz, BS Handa, ... Journal of biological chemistry 284 (40), 27195-27210, 2009 | 31 | 2009 |
| Inverse regulation of preproendothelin-1 and endothelin-converting enzyme-1β genes in cardiac cells by mechanical load S Pikkarainen, H Tokola, R Kerkelä, M Ilves, M Mäkinen, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2006 | 31 | 2006 |
