| Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells ES Lippmann, SM Azarin, JE Kay, RA Nessler, HK Wilson, A Al-Ahmad, ... Nature biotechnology 30 (8), 783-791, 2012 | 774 | 2012 |
| In vitro models of the blood–brain barrier: an overview of commonly used brain endothelial cell culture models and guidelines for their use HC Helms, NJ Abbott, M Burek, R Cecchelli, PO Couraud, MA Deli, ... Journal of Cerebral Blood Flow & Metabolism 36 (5), 862-890, 2016 | 742 | 2016 |
| Blood–brain barrier transport of therapeutics via receptor-mediation AR Jones, EV Shusta Pharmaceutical research 24, 1759-1771, 2007 | 617 | 2007 |
| A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources ES Lippmann, A Al-Ahmad, SM Azarin, SP Palecek, EV Shusta Scientific reports 4 (1), 4160, 2014 | 486 | 2014 |
| Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies TE Park, N Mustafaoglu, A Herland, R Hasselkus, R Mannix, ... Nature communications 10 (1), 2621, 2019 | 469 | 2019 |
| In vitro evolution of a T cell receptor with high affinity for peptide/MHC PD Holler, PO Holman, EV Shusta, S O'Herrin, KD Wittrup, DM Kranz Proceedings of the National Academy of Sciences 97 (10), 5387-5392, 2000 | 407 | 2000 |
| Targeting receptor-mediated transport for delivery of biologics across the blood-brain barrier JM Lajoie, EV Shusta Annual review of pharmacology and toxicology 55, 613-631, 2015 | 385 | 2015 |
| Efficient differentiation of human pluripotent stem cells to endothelial progenitors via small-molecule activation of WNT signaling X Lian, X Bao, A Al-Ahmad, J Liu, Y Wu, W Dong, KK Dunn, EV Shusta, ... Stem cell reports 3 (5), 804-816, 2014 | 348 | 2014 |
| Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments EV Shusta, RT Raines, A Plückthun, KD Wittrup Nature biotechnology 16 (8), 773-777, 1998 | 348 | 1998 |
| Directed evolution of a stable scaffold for T-cell receptor engineering EV Shusta, PD Holler, MC Kieke, DM Kranz, KD Wittrup Nature biotechnology 18 (7), 754-759, 2000 | 342 | 2000 |
| Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency EV Shusta, MC Kieke, E Parke, DM Kranz, KD Wittrup Journal of molecular biology 292 (5), 949-956, 1999 | 318 | 1999 |
| Selection of functional T cell receptor mutants from a yeast surface-display library MC Kieke, EV Shusta, ET Boder, L Teyton, KD Wittrup, DM Kranz Proceedings of the National Academy of Sciences 96 (10), 5651-5656, 1999 | 287 | 1999 |
| A decade of yeast surface display technology: where are we now? EV Shusta, LR Pepper, YK Cho, ET Boder Combinatorial chemistry & high throughput screening 11 (2), 127-134, 2008 | 279 | 2008 |
| An isogenic blood–brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells SG Canfield, MJ Stebbins, BS Morales, SW Asai, GD Vatine, ... Journal of neurochemistry 140 (6), 874-888, 2017 | 239 | 2017 |
| Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells T Qian, SE Maguire, SG Canfield, X Bao, WR Olson, EV Shusta, ... Science advances 3 (11), e1701679, 2017 | 210 | 2017 |
| Yeast cell surface display of proteins and uses thereof MC Kieke, KD Wittrup, ET Boder, DM Kranz, E Shusta US Patent 6,300,065, 2001 | 207 | 2001 |
| Modeling psychomotor retardation using iPSCs from MCT8-deficient patients indicates a prominent role for the blood-brain barrier GD Vatine, A Al-Ahmad, BK Barriga, S Svendsen, A Salim, L Garcia, ... Cell stem cell 20 (6), 831-843. e5, 2017 | 204 | 2017 |
| Puromycin‐purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction AR Calabria, C Weidenfeller, AR Jones, HE De Vries, EV Shusta Journal of neurochemistry 97 (4), 922-933, 2006 | 180 | 2006 |
| Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties MJ Stebbins, BD Gastfriend, SG Canfield, MS Lee, D Richards, ... Science advances 5 (3), eaau7375, 2019 | 154 | 2019 |
| Differentiating embryonic neural progenitor cells induce blood–brain barrier properties C Weidenfeller, CN Svendsen, EV Shusta Journal of neurochemistry 101 (2), 555-565, 2007 | 148 | 2007 |
