Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis F Pacchiano, F Carta, PC McDonald, Y Lou, D Vullo, A Scozzafava, ... Journal of medicinal chemistry 54 (6), 1896-1902, 2011 | 526 | 2011 |
Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrases S Del Prete, D Vullo, GM Fisher, KT Andrews, SA Poulsen, C Capasso, ... Bioorganic & Medicinal Chemistry Letters 24 (18), 4389-4396, 2014 | 356 | 2014 |
Carbonic anhydrase in the scleractinian coral Stylophora pistillata: characterization, localization, and role in biomineralization A Moya, S Tambutté, A Bertucci, E Tambutté, S Lotto, D Vullo, CT Supuran, ... Journal of Biological Chemistry 283 (37), 25475-25484, 2008 | 274 | 2008 |
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides—a new target for the design of antitumor and antiglaucoma drugs? D Vullo, A Innocenti, I Nishimori, J Pastorek, A Scozzafava, S Pastoreková, ... Bioorganic & medicinal chemistry letters 15 (4), 963-969, 2005 | 266 | 2005 |
Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides D Vullo, M Franchi, E Gallori, J Pastorek, A Scozzafava, S Pastorekova, ... Bioorganic & medicinal chemistry letters 13 (6), 1005-1009, 2003 | 251 | 2003 |
Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides BL Wilkinson, LF Bornaghi, TA Houston, A Innocenti, D Vullo, CT Supuran, ... Journal of medicinal chemistry 50 (7), 1651-1657, 2007 | 243 | 2007 |
Sulfocoumarins (1, 2-benzoxathiine-2, 2-dioxides): a class of potent and isoform-selective inhibitors of tumor-associated carbonic anhydrases K Tars, D Vullo, A Kazaks, J Leitans, A Lends, A Grandane, R Zalubovskis, ... Journal of Medicinal Chemistry 56 (1), 293-300, 2013 | 228 | 2013 |
Carbonic anhydrase inhibitors: Interactions of phenols with the 12 catalytically active mammalian isoforms (CA I–XIV) A Innocenti, D Vullo, A Scozzafava, CT Supuran Bioorganic & medicinal chemistry letters 18 (5), 1583-1587, 2008 | 221 | 2008 |
Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors I Nishimori, D Vullo, A Innocenti, A Scozzafava, A Mastrolorenzo, ... Journal of medicinal chemistry 48 (24), 7860-7866, 2005 | 210 | 2005 |
Structure and inhibition of the CO2-sensing carbonic anhydrase Can2 from the pathogenic fungus Cryptococcus neoformans C Schlicker, RA Hall, D Vullo, S Middelhaufe, M Gertz, CT Supuran, ... Journal of molecular biology 385 (4), 1207-1220, 2009 | 207 | 2009 |
Carbonic anhydrase inhibitors: the β-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors I Nishimori, T Minakuchi, T Kohsaki, S Onishi, H Takeuchi, D Vullo, ... Bioorganic & medicinal chemistry letters 17 (13), 3585-3594, 2007 | 200 | 2007 |
A spectroscopic study of the reaction of NAMI, a novel ruthenium (III) anti‐neoplastic complex, with bovine serum albumin L Messori, P Orioli, D Vullo, E Alessio, E Iengo European journal of biochemistry 267 (4), 1206-1213, 2000 | 198 | 2000 |
Designing of novel carbonic anhydrase inhibitors and activators CT Supuran, D Vullo, G Manole, A Casini, A Scozzafava Current Medicinal Chemistry-Cardiovascular & Hematological Agents 2 (1), 49-68, 2004 | 193 | 2004 |
Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the α-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate … I Nishimori, T Minakuchi, K Morimoto, S Sano, S Onishi, H Takeuchi, ... Journal of medicinal chemistry 49 (6), 2117-2126, 2006 | 192 | 2006 |
Carbonic anhydrase inhibitors. Design of selective, membrane-impermeant inhibitors targeting the human tumor-associated isozyme IX JR Casey, PE Morgan, D Vullo, A Scozzafava, A Mastrolorenzo, ... Journal of medicinal chemistry 47 (9), 2337-2347, 2004 | 192 | 2004 |
Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1, 3, 5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II … V Garaj, L Puccetti, G Fasolis, JY Winum, JL Montero, A Scozzafava, ... Bioorganic & medicinal chemistry letters 15 (12), 3102-3108, 2005 | 185 | 2005 |
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides D Vullo, J Voipio, A Innocenti, C Rivera, H Ranki, A Scozzafava, K Kaila, ... Bioorganic & medicinal chemistry letters 15 (4), 971-976, 2005 | 183 | 2005 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff’s bases incorporating chromone and aromatic … L Puccetti, G Fasolis, D Vullo, ZH Chohan, A Scozzafava, CT Supuran Bioorganic & medicinal chemistry letters 15 (12), 3096-3101, 2005 | 182 | 2005 |
Carbonic anhydrase inhibitors. Inhibition of mitochondrial isozyme V with aromatic and heterocyclic sulfonamides D Vullo, M Franchi, E Gallori, J Antel, A Scozzafava, CT Supuran Journal of medicinal chemistry 47 (5), 1272-1279, 2004 | 181 | 2004 |
Carbonic anhydrase inhibitors. Inhibition of tumor-associated isozyme IX by halogenosulfanilamide and halogenophenylaminobenzolamide derivatives MA Ilies, D Vullo, J Pastorek, A Scozzafava, M Ilies, MT Caproiu, ... Journal of medicinal chemistry 46 (11), 2187-2196, 2003 | 178 | 2003 |