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Anita Chandra
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SARS-CoV-2 evolution during treatment of chronic infection
SA Kemp, DA Collier, RP Datir, IATM Ferreira, S Gayed, A Jahun, ...
Nature 592 (7853), 277-282, 2021
9002021
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage
I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ...
Science 342 (6160), 866-871, 2013
6242013
Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: a large patient cohort study
TI Coulter, A Chandra, CM Bacon, J Babar, J Curtis, N Screaton, ...
Journal of Allergy and Clinical Immunology 139 (2), 597-606. e4, 2017
5912017
Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease
KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ...
The American Journal of Human Genetics 100 (1), 75-90, 2017
4052017
Disease evolution and response to rapamycin in activated phosphoinositide 3-kinase δ syndrome: the european society for immunodeficiencies-activated phosphoinositide 3-kinase δ …
ME Maccari, H Abolhassani, A Aghamohammadi, A Aiuti, O Aleinikova, ...
Frontiers in immunology 9, 344586, 2018
3412018
PI3Kδ and primary immunodeficiencies
CL Lucas, A Chandra, S Nejentsev, AM Condliffe, K Okkenhaug
Nature Reviews Immunology 16 (11), 702-714, 2016
3052016
Respiratory manifestations of the activated phosphoinositide 3-kinase delta syndrome
AM Condliffe, A Chandra
Frontiers in immunology 9, 335203, 2018
2222018
Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans
P Tuijnenburg, HL Allen, SO Burns, D Greene, MH Jansen, E Staples, ...
Journal of allergy and clinical immunology 142 (4), 1285-1296, 2018
2072018
Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation
SA Kemp, DA Collier, R Datir, IATM Ferreira, S Gayed, A Jahun, ...
MedRxiv, 2020
1792020
Whole-genome sequencing of a sporadic primary immunodeficiency cohort
JED Thaventhiran, H Lango Allen, OS Burren, W Rae, D Greene, ...
Nature 583 (7814), 90-95, 2020
1612020
Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension
C Hadinnapola, M Bleda, M Haimel, N Screaton, A Swift, P Dorfmüller, ...
Circulation 136 (21), 2022-2033, 2017
1232017
COVID-19 Genomics UK (COG-UK) Consortium
SA Kemp, DA Collier, RP Datir, I Ferreira, S Gayed, A Jahun, M Hosmillo, ...
Sharrocks K, Blane E, Modis Y, Leigh KE, Briggs JAG, van Gils MJ, Smith KGC …, 2021
1012021
Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations
T Lorenzini, M Fliegauf, N Klammer, N Frede, M Proietti, A Bulashevska, ...
Journal of Allergy and Clinical Immunology 146 (4), 901-911, 2020
962020
Respiratory disease in common variable immunodeficiency and other primary immunodeficiency disorders
FA Hampson, A Chandra, NJ Screaton, A Condliffe, DS Kumararatne, ...
Clinical radiology 67 (6), 587-595, 2012
842012
Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity
RC Ferreira, HZ Simons, WS Thompson, DB Rainbow, X Yang, AJ Cutler, ...
Journal of Autoimmunity 84, 75-86, 2017
762017
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner
AK Stark, A Chandra, K Chakraborty, R Alam, V Carbonaro, J Clark, ...
Nature communications 9 (1), 3174, 2018
732018
Comprehensive cancer-predisposition gene testing in an adult multiple primary tumor series shows a broad range of deleterious variants and atypical tumor phenotypes
J Whitworth, PS Smith, JE Martin, H West, A Luchetti, F Rodger, G Clark, ...
The American Journal of Human Genetics 103 (1), 3-18, 2018
602018
Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate
JA Bibby, HA Purvis, T Hayday, A Chandra, K Okkenhaug, S Rosenzweig, ...
Nature communications 11 (1), 3412, 2020
582020
Bi-allelic loss-of-function CACNA1B mutations in progressive epilepsy-dyskinesia
KM Gorman, E Meyer, D Grozeva, E Spinelli, A McTague, A Sanchis-Juan, ...
The American Journal of Human Genetics 104 (5), 948-956, 2019
582019
Cowden's syndrome with immunodeficiency
MJ Browning, A Chandra, V Carbonaro, K Okkenhaug, J Barwell
Journal of Medical Genetics 52 (12), 856-859, 2015
552015
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