|Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours|
LA Donehower, M Harvey, BL Slagle, MJ McArthur, CA Montgomery, ...
Nature 356 (6366), 215-221, 1992
|Comprehensive and integrative genomic characterization of hepatocellular carcinoma|
A Ally, M Balasundaram, R Carlsen, E Chuah, A Clarke, N Dhalla, RA Holt, ...
Cell 169 (7), 1327-1341. e23, 2017
|Trans-ancestry mutational landscape of hepatocellular carcinoma genomes|
Y Totoki, K Tatsuno, KR Covington, H Ueda, CJ Creighton, M Kato, S Tsuji, ...
Nature genetics 46 (12), 1267, 2014
|Hepatitis B virus X protein interferes with cellular DNA repair|
SA Becker, TH Lee, JS Butel, BL Slagle
Journal of virology 72 (1), 266-272, 1998
|Elevated expression of the miR-17–92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype|
E Connolly, M Melegari, P Landgraf, T Tchaikovskaya, BC Tennant, ...
The American journal of pathology 173 (3), 856-864, 2008
|p53 mutations cluster at codon 249 in hepatitis B virus-positive hepatocellular carcinomas from China|
KA Scorsone, YZ Zhou, JS Butel, BL Slagle
Cancer research 52 (6), 1635-1638, 1992
|Increased sensitivity to the hepatocarcinogen diethylnitrosamine in transgenic mice carrying the hepatitis B virus X gene|
BL Slagle, TH Lee, D Medina, MJ Finegold, JS Butel
Molecular Carcinogenesis: Published in cooperation with the University of …, 1996
|Enhancement of hepatitis B virus replication by the regulatory X protein in vitro and in vivo|
VV Keasler, AJ Hodgson, CR Madden, BL Slagle
Journal of virology 81 (6), 2656-2662, 2007
|Hepatitis B virus integration event in human chromosome 17p near the p53 gene identifies the region of the chromosome commonly deleted in virus-positive hepatocellular carcinomas|
BL Slagle, YZ Zhou, JS Butel
Cancer Research 51 (1), 49-54, 1991
|Enhancement of hepatitis B virus replication by its X protein in transgenic mice|
Z Xu, TSB Yen, L Wu, CR Madden, W Tan, BL Slagle, J Ou
Journal of virology 76 (5), 2579-2584, 2002
|Hepatitis B virus X protein acts as a tumor promoter in development of diethylnitrosamine-induced preneoplastic lesions|
CR Madden, MJ Finegold, BL Slagle
Journal of virology 75 (8), 3851-3858, 2001
|Hepatitis B virus regulatory HBx protein binds to adaptor protein IPS-1 and inhibits the activation of beta interferon|
M Kumar, SY Jung, AJ Hodgson, CR Madden, J Qin, BL Slagle
Journal of virology 85 (2), 987-995, 2011
|Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory …|
AR Sepulveda, MJ Finegold, B Smith, BL Slagle, JL DeMayo, RF Shen, ...
Cancer Research 49 (21), 6108-6117, 1989
|The naturally occurring mutants of DDB are impaired in stimulating nuclear import of the p125 subunit and E2F1-activated transcription|
P Shiyanov, SA Hayes, M Donepudi, AF Nichols, S Linn, BL Slagle, ...
Molecular and cellular biology 19 (7), 4935-4943, 1999
|Deletion of the E‐cadherin gene in hepatitis B virus–positive chinese hepatocellular carcinomas|
BL Slagle, YZ Zhou, W Birchmeier, KA Scorsone
Hepatology 18 (4), 757-762, 1993
|Stimulation of cellular proliferation by hepatitis B virus X protein|
CR Madden, BL Slagle
Disease markers 17 (3), 153-157, 2001
|Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue|
I Jaitovich-Groisman, N Benlimame, BL Slagle, MH Perez, L Alpert, ...
Journal of Biological Chemistry 276 (17), 14124-14132, 2001
|Overexpression of insulin receptor substrate‐1 and hepatitis Bx genes causes premalignant alterations in the liver|
L Longato, S de la Monte, N Kuzushita, M Horimoto, AB Rogers, ...
Hepatology 49 (6), 1935-1943, 2009
|Structural analysis of a hepatitis B virus genome integrated into chromosome 17p of a human hepatocellular carcinoma|
YZ Zhou, BL Slagle, LA Donehower, P Vantuinen, DH Ledbetter, JS Butel
Journal of Virology 62 (11), 4224-4231, 1988
|Expression of hepatitis B virus X protein does not alter the accumulation of spontaneous mutations in transgenic mice|
CR Madden, MJ Finegold, BL Slagle
Journal of virology 74 (11), 5266-5272, 2000