Katarzyna Piróg
Katarzyna Piróg
Institute of Genetic Medicine, Newcastle University, UK
Verified email at ncl.ac.uk
TitleCited byYear
Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C …
KA Piróg-Garcia, RS Meadows, L Knowles, D Heinegĺrd, DJ Thornton, ...
Human molecular genetics 16 (17), 2072-2088, 2007
782007
A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia
F Suleman, B Gualeni, HJ Gregson, MP Leighton, KA Piróg, S Edwards, ...
Human mutation 33 (1), 218-231, 2012
362012
A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia
KA Pirog, O Jaka, Y Katakura, RS Meadows, KE Kadler, ...
Human molecular genetics 19 (1), 52-64, 2009
352009
Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia
KA Piróg, A Irman, S Young, P Halai, PA Bell, RP Boot-Handford, ...
PloS one 9 (2), e85145, 2014
262014
Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and …
TL Cameron, IL Gresshoff, KM Bell, KA Pirog, L Sampurno, CL Hartley, ...
Osteoarthritis and cartilage 23 (4), 661-670, 2015
252015
New therapeutic targets in rare genetic skeletal diseases
MD Briggs, PA Bell, MJ Wright, KA Pirog
Expert opinion on orphan drugs 3 (10), 1137-1154, 2015
192015
The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress
MD Briggs, PA Bell, KA Pirog
International journal of molecular medicine 35 (6), 1483-1492, 2015
172015
Skeletal Dysplasias Associated with Mild Myopathy—A Clinical and Molecular Review
A Katarzyna, MD Briggs
14*2010
Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases
KA Piróg, Y Katakura, A Mironov, MD Briggs
PloS one 8 (11), e82412, 2013
72013
Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation
PA Bell, KA Piróg, M Fresquet, DJ Thornton, RP Boot‐Handford, ...
Arthritis & Rheumatism 64 (5), 1529-1539, 2012
62012
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification
C Paganini, L Monti, R Costantini, R Besio, S Lecci, M Biggiogera, K Tian, ...
Matrix Biology 81, 70-90, 2019
32019
Changes in Bcl-2 expression in vaccinia virus-infected human peripheral blood monocytes
KA Pirog, AK Kowalczyk, HB Rokita
Viral Immunology 18 (1), 224-231, 2005
22005
XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease
KA Pirog, EP Dennis, CL Hartley, RM Jackson, J Soul, JM Schwartz, ...
PLoS genetics 15 (7), e1008215, 2019
2019
Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis
PA Bell, EP Dennis, CL Hartley, RM Jackson, A Porter, RP Boot-Handford, ...
Cell Stress and Chaperones 24 (1), 159-173, 2019
2019
CANT1 role in proteoglycan synthesis: an in vivo study with a mouse model of Desbuquois dysplasia type 1
C Paganini, R Costantini, L Monti, CG Tota, A Lundari, M Biggiogera, ...
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 99 (6), A50-A50, 2018
2018
Pseudoachondroplasia and Multiple Epiphyseal Dysplasia: Molecular Genetics, Disease Mechanisms and Therapeutic Targets
MD Briggs, P Bell, KA Piróg
Cartilage, 135-153, 2017
2017
3D Modelling of zonally stratified cartilage tissue
T Ruiz, D las Heras, TJ Porter, KA Pirog
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 97 (6), A21-A21, 2016
2016
The role of Creld2 in skeletal development and homeostasis
E Dennis, M Capulli, A Teti, K Pirog, M Briggs
43rd Annual European Calcified Tissue Society Congress 5, 2016
2016
Tissue Engineering Approaches for the Study and Therapeutic Intervention in Osteoarthritis
T de-las-Heras-Ruiz, KA Pirog
Osteoarthritis, 2016
2016
Shared therapeutic targets in genetic skeletal diseases
MD Briggs, KA Pirog, PA Bell
7th International Conference on Children 4, 2015
2015
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Articles 1–20