Katarzyna Piróg
Katarzyna Piróg
Institute of Genetic Medicine, Newcastle University, UK
Verified email at ncl.ac.uk
Cited by
Cited by
Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C …
KA Piróg-Garcia, RS Meadows, L Knowles, D Heinegĺrd, DJ Thornton, ...
Human molecular genetics 16 (17), 2072-2088, 2007
A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia
F Suleman, B Gualeni, HJ Gregson, MP Leighton, KA Piróg, S Edwards, ...
Human mutation 33 (1), 218-231, 2012
A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia
KA Pirog, O Jaka, Y Katakura, RS Meadows, KE Kadler, ...
Human molecular genetics 19 (1), 52-64, 2010
New therapeutic targets in rare genetic skeletal diseases
MD Briggs, PA Bell, MJ Wright, KA Pirog
Expert opinion on orphan drugs 3 (10), 1137-1154, 2015
Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and …
TL Cameron, IL Gresshoff, KM Bell, KA Piróg, L Sampurno, CL Hartley, ...
Osteoarthritis and cartilage 23 (4), 661-670, 2015
The utility of mouse models to provide information regarding the pathomolecular mechanisms in human genetic skeletal diseases: The emerging role of endoplasmic reticulum stress
MD Briggs, PA Bell, KA Pirog
International journal of molecular medicine 35 (6), 1483-1492, 2015
Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia
KA Piróg, A Irman, S Young, P Halai, PA Bell, RP Boot-Handford, ...
PloS one 9 (2), e85145, 2014
Calcium activated nucleotidase 1 (CANT1) is critical for glycosaminoglycan biosynthesis in cartilage and endochondral ossification
C Paganini, L Monti, R Costantini, R Besio, S Lecci, M Biggiogera, K Tian, ...
Matrix Biology 81, 70-90, 2019
Skeletal Dysplasias Associated with Mild Myopathy—A Clinical and Molecular Review
A Katarzyna, MD Briggs
Mesencephalic astrocyte-derived neurotropic factor is an important factor in chondrocyte ER homeostasis
PA Bell, EP Dennis, CL Hartley, RM Jackson, A Porter, RP Boot-Handford, ...
Cell Stress and Chaperones 24 (1), 159-173, 2019
Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases
KA Piróg, Y Katakura, A Mironov, MD Briggs
PloS one 8 (11), e82412, 2013
XBP1 signalling is essential for alleviating mutant protein aggregation in ER-stress related skeletal disease
KA Pirog, EP Dennis, CL Hartley, RM Jackson, J Soul, JM Schwartz, ...
PLoS genetics 15 (7), e1008215, 2019
Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation
PA Bell, KA Piróg, M Fresquet, DJ Thornton, RP Boot‐Handford, ...
Arthritis & Rheumatism 64 (5), 1529-1539, 2012
microRNA-seq of cartilage reveals an overabundance of miR-140-3p which contains functional isomiRs
S Woods, S Charlton, K Cheung, Y Hao, J Soul, LN Reynard, N Crowe, ...
RNA 26 (11), 1575-1588, 2020
New developments in chondrocyte ER stress and related diseases
MD Briggs, EP Dennis, HF Dietmar, KA Pirog
F1000Research 9, 2020
CRELD2 is a novel LRP1 chaperone that regulates noncanonical WNT signaling in skeletal development
EP Dennis, SM Edwards, RM Jackson, CL Hartley, D Tsompani, M Capulli, ...
Journal of Bone and Mineral Research 35 (8), 1452-1469, 2020
Changes in Bcl-2 expression in vaccinia virus-infected human peripheral blood monocytes
KA Pirog, AK Kowalczyk, HB Rokita
Viral Immunology 18 (1), 224-231, 2005
Increased hippocampal excitability in miR-324-null mice
DJ Hayman, T Modebadze, S Charlton, K Cheung, J Soul, H Lin, Y Hao, ...
Scientific Reports 11 (1), 1-17, 2021
CANT1 role in proteoglycan synthesis: an in vivo study with a mouse model of Desbuquois dysplasia type 1
C Paganini, R Costantini, L Monti, CG Tota, A Lundari, M Biggiogera, ...
Pseudoachondroplasia and Multiple Epiphyseal Dysplasia: Molecular Genetics, Disease Mechanisms and Therapeutic Targets
MD Briggs, P Bell, KA Piróg
Cartilage, 135-153, 2017
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