| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky Autophagy, 0 | 13508* | |
| Mechanisms of acute axonal degeneration in the optic nerve in vivo J Knöferle, JC Koch, T Ostendorf, U Michel, V Planchamp, P Vutova, ... Proceedings of the National Academy of Sciences 107 (13), 6064-6069, 2010 | 318 | 2010 |
| ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells P Lingor, L Tönges, N Pieper, C Bermel, E Barski, V Planchamp, M Bähr Brain 131 (1), 250-263, 2008 | 278 | 2008 |
| Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson’s disease L Tönges, T Frank, L Tatenhorst, KA Saal, JC Koch, ÉM Szegő, M Bähr, ... Brain 135 (11), 3355-3370, 2012 | 195 | 2012 |
| ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS JC Koch, L Tönges, E Barski, U Michel, M Bähr, P Lingor Cell death & disease 5 (5), e1225-e1225, 2014 | 188 | 2014 |
| ROCK inhibition in models of neurodegeneration and its potential for clinical translation JC Koch, L Tatenhorst, AE Roser, KA Saal, L Tönges, P Lingor Pharmacology & Therapeutics 189, 1-21, 2018 | 184 | 2018 |
| The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin A Nölle, A Zeug, J van Bergeijk, L Tönges, R Gerhard, H Brinkmann, ... Human molecular genetics 20 (24), 4865-4878, 2011 | 171 | 2011 |
| Trial of cinpanemab in early Parkinson’s disease AE Lang, AD Siderowf, EA Macklin, W Poewe, DJ Brooks, HH Fernandez, ... New England Journal of Medicine 387 (5), 408-420, 2022 | 159 | 2022 |
| Axonal degeneration as a therapeutic target in the CNS P Lingor, JC Koch, L Tönges, M Bähr Cell and tissue research 349, 289-311, 2012 | 147 | 2012 |
| Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons JC Koch, F Bitow, J Haack, Z d'Hedouville, JN Zhang, L Tönges, U Michel, ... Cell death & disease 6 (7), e1811-e1811, 2015 | 144 | 2015 |
| Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons L Tönges, P Lingor, R Egle, GPH Dietz, A Fahr, M Bähr Rna 12 (7), 1431-1438, 2006 | 140 | 2006 |
| Fasudil attenuates aggregation of α-synuclein in models of Parkinson’s disease L Tatenhorst, K Eckermann, V Dambeck, L Fonseca-Ornelas, H Walle, ... Acta neuropathologica communications 4, 1-17, 2016 | 135 | 2016 |
| Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis L Tönges, R Günther, M Suhr, J Jansen, A Balck, KA Saal, E Barski, ... Glia 62 (2), 217-232, 2014 | 125 | 2014 |
| ROCKing regeneration: Rho kinase inhibition as molecular target for neurorestoration L Tönges, JC Koch, M Bähr, P Lingor Frontiers in molecular neuroscience 4, 39, 2011 | 113 | 2011 |
| TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice TR Doeppner, F Nagel, GPH Dietz, J Weise, L Tönges, S Schwarting, ... Journal of Cerebral Blood Flow & Metabolism 29 (6), 1187-1196, 2009 | 112 | 2009 |
| Tat‐Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson’s disease F Nagel, BH Falkenburger, L Tönges, S Kowsky, C Pöppelmeyer, ... Journal of neurochemistry 105 (3), 853-864, 2008 | 109 | 2008 |
| Association of blood pressure with outcomes in acute stroke thrombectomy K Malhotra, N Goyal, AH Katsanos, A Filippatou, EA Mistry, P Khatri, ... Hypertension 75 (3), 730-739, 2020 | 97 | 2020 |
| Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation TR Doeppner, TAS Ewert, L Tönges, J Herz, A Zechariah, A ElAli, ... Stem cells 30 (6), 1297-1310, 2012 | 97 | 2012 |
| Classification of advanced stages of Parkinson’s disease: translation into stratified treatments R Krüger, J Klucken, D Weiss, L Tönges, P Kolber, S Unterecker, ... Journal of Neural Transmission 124, 1015-1027, 2017 | 96 | 2017 |
| GluN2D-containing NMDA receptors-mediate synaptic currents in hippocampal interneurons and pyramidal cells in juvenile mice J Engelhardt, C Bocklisch, L Tönges, A Herb, M Mishina, H Monyer Frontiers in cellular neuroscience 9, 95, 2015 | 96 | 2015 |
