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G Michael Blackburn
G Michael Blackburn
Professor of Chemical Biology, University of Sheffield
Verified email at sheffield.ac.uk - Homepage
Title
Cited by
Cited by
Year
Nucleic acids in chemistry and biology
GM Blackburn
Royal Society of Chemistry, 2006
13442006
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design
RJ Russell, LF Haire, DJ Stevens, PJ Collins, YP Lin, GM Blackburn, ...
Nature 443 (7107), 45-49, 2006
9822006
Clodronate and liposome‐encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′‐(β, γ‐dichloromethylene) triphosphate, by mammalian cells in vitro
JC Frith, J Mönkkönen, GM Blackburn, RGG Russell, MJ Rogers
Journal of Bone and Mineral Research 12 (9), 1358-1367, 1997
6261997
Structure and catalytic mechanism of the human histone methyltransferase SET7/9
B Xiao, C Jing, JR Wilson, PA Walker, N Vasisht, G Kelly, S Howell, ...
Nature 421 (6923), 652-656, 2003
4682003
Uracil-DNA glycosylase–DNA substrate and product structures: Conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
SS Parikh, G Walcher, GD Jones, G Slupphaug, HE Krokan, ...
Proceedings of the National Academy of Sciences 97 (10), 5083-5088, 2000
3142000
Crystal structure and functional analysis of the histone methyltransferase SET7/9
JR Wilson, C Jing, PA Walker, SR Martin, SA Howell, GM Blackburn, ...
Cell 111 (1), 105-115, 2002
2882002
Uracil-DNA glycosylase acts by substrate autocatalysis
AR Dinner, GM Blackburn, M Karplus
Nature 413 (6857), 752-755, 2001
2662001
The synthesis and metal binding characteristics of novel, isopolar phosphonate analogues of nucleotides
GM Blackburn, DE Kent, F Kolkmann
Journal of the Chemical Society, Perkin Transactions 1, 1119-1125, 1984
2651984
Phosphonates as analogues of biological phosphates
GM Blackburn
1981981
Why did Nature select phosphate for its dominant roles in biology?
MW Bowler, MJ Cliff, JP Waltho, GM Blackburn
New Journal of Chemistry 34 (5), 784-794, 2010
1882010
Genetic, biochemical, and crystallographic characterization of Fhit–substrate complexes as the active signaling form of Fhit
HC Pace, PN Garrison, AK Robinson, LD Barnes, A Draganescu, ...
Proceedings of the National Academy of Sciences 95 (10), 5484-5489, 1998
1821998
The mechanism of the aminolysis of methyl formate
GM Blackburn, WP Jencks
Journal of the American Chemical Society 90 (10), 2638-2645, 1968
1821968
Monofluoro-and difluoro-methylenebisphosphonic acids: isopolar analogues of pyrophosphoric acid
GM Blackburn, DA England, F Kolkmann
Journal of the Chemical Society, Chemical Communications, 930-932, 1981
1781981
Antibiotic recognition by binuclear metallo-β-lactamases revealed by X-ray crystallography
J Spencer, J Read, RB Sessions, S Howell, GM Blackburn, SJ Gamblin
Journal of the American Chemical Society 127 (41), 14439-14444, 2005
1522005
Bisphosphonates are incorporated into adenine nucleotides by human aminoacyl-tRNA synthetase enzymes
MJ Rogers, RJ Brown, V Hodkin, GM Blackburn, RGG Russell, DJ Watts
Biochemical and biophysical research communications 224 (3), 863-869, 1996
1521996
Toward antibody-directed" abzyme" prodrug therapy, ADAPT: carbamate prodrug activation by a catalytic antibody and its in vitro application to human tumor cell killing.
P Wentworth, A Datta, D Blakey, T Boyle, LJ Partridge, GM Blackburn
Proceedings of the National Academy of Sciences 93 (2), 799-803, 1996
1491996
Synthesis of α-and γ-fluoroalkylphosphonates
GM Blackburn, DE Kent
Journal of the Chemical Society, Perkin Transactions 1, 913-917, 1986
1431986
Incorporation of bisphosphonates into adenine nucleotides by amoebae of the cellular slime mould Dictyostelium discoideum
MJ Rogers, X Ji, RGG Russell, GM Blackburn, MP Williamson, AV Bayless, ...
Biochemical Journal 303 (1), 303-311, 1994
1371994
Derivatives of tamoxifen. Dependence of antiestrogenicity on the 4-substituent
R McCague, G Leclercq, N Legros, J Goodman, GM Blackburn, M Jarman, ...
Journal of medicinal chemistry 32 (12), 2527-2533, 1989
1171989
Turnover-based in vitro selection and evolution of biocatalysts from a fully synthetic antibody library
S Cesaro-Tadic, D Lagos, A Honegger, JH Rickard, LJ Partridge, ...
Nature biotechnology 21 (6), 679-685, 2003
1102003
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