Steven K Dower
Steven K Dower
Emeritus Professor , University of Sheffield: Senior Director, CSL
Verified email at
TitleCited byYear
A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins
CA Smith, T Davis, D Anderson, L Solam, MP Beckmann, R Jerzy, ...
Science 248 (4958), 1019-1023, 1990
Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4
F Colotta, F Re, M Muzio, R Bertini, N Polentarutti, M Sironi, JG Giri, ...
Science 261 (5120), 472-475, 1993
cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily.
S JE, M CJ, C D, W MB, MD HR, MM CJ, G CE, W JM, J JL, C SM, F D, ...
science 241, 585-589, 1988
Rapid secretion of interleukin-1β by microvesicle shedding
A MacKenzie, HL Wilson, E Kiss-Toth, SK Dower, RA North, A Surprenant
Immunity 15 (5), 825-835, 2001
Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA
EW Raines, SK Dower, R Ross
Science 243 (4889), 393-396, 1989
Regulation of Toll-like receptors in human monocytes and dendritic cells
A Visintin, A Mazzoni, JH Spitzer, DH Wyllie, SK Dower, DM Segal
The Journal of Immunology 166 (1), 249-255, 2001
Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily
RG Goodwin, D Friend, SF Ziegler, R Jerzy, BA Falk, S Gimpel, D Cosman, ...
Cell 60 (6), 941-951, 1990
Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas
HJ Gruss, SK Dower
Blood 85 (12), 3378-3404, 1995
A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling
A Bowie, E Kiss-Toth, JA Symons, GL Smith, SK Dower, LAJ O'Neill
Proceedings of the National Academy of Sciences 97 (18), 10162-10167, 2000
The cell surface receptors for interleukin-1α and interleukin-1β are identical
SK Dower, SR Kronheim, TP Hopp, M Cantrell, M Deeley, S Gillis, ...
Nature 324 (6094), 266, 1986
Detection and characterization of high affinity plasma membrane receptors for human interleukin 1.
SK Dower, SR Kronheim, CJ March, PJ Conlon, TP Hopp, S Gillis, ...
Journal of Experimental Medicine 162 (2), 501-515, 1985
The type II ‘decoy’receptor: a novel regulatory pathway for interleukin 1
F Colotta, SK Dower, JE Sims, A Mantovani
Immunology today 15 (12), 562-566, 1994
The interleukin-1 receptor binds the human interleukin-1 alpha precursor but not the interleukin-1 beta precursor.
B Mosley, DL Urdal, KS Prickett, A Larsen, D Cosman, PJ Conlon, S Gillis, ...
Journal of biological chemistry 262 (7), 2941-2944, 1987
Toll-like receptor (TLR) 2 and TLR4 in human peripheral blood granulocytes: a critical role for monocytes in leukocyte lipopolysaccharide responses
I Sabroe, EC Jones, LR Usher, MKB Whyte, SK Dower
The Journal of Immunology 168 (9), 4701-4710, 2002
Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses
DH Wyllie, E Kiss-Toth, A Visintin, SC Smith, S Boussouf, DM Segal, ...
The Journal of Immunology 165 (12), 7125-7132, 2000
Selective roles for Toll-like receptor (TLR) 2 and TLR4 in the regulation of neutrophil activation and life span
I Sabroe, LR Prince, EC Jones, MJ Horsburgh, SJ Foster, SN Vogel, ...
The Journal of Immunology 170 (10), 5268-5275, 2003
Cloning the interleukin 1 receptor from human T cells
JE Sims, RB Acres, CE Grubin, CJ McMahan, JM Wignall, CJ March, ...
Proceedings of the National Academy of Sciences 86 (22), 8946-8950, 1989
Cloning, sequence and expression of human interleukin-2 receptor
D Cosman, DP Cerretti, A Larsen, L Park, C March, S Dower, S Gillis, ...
Nature 312 (5996), 768, 1984
IL-1Rrp is a novel receptor-like molecule similar to the type I interleukin-1 receptor and its homologues T1/ST2 and IL-1R AcP
P Parnet, KE Garka, TP Bonnert, SK Dower, JE Sims
Journal of Biological Chemistry 271 (8), 3967-3970, 1996
Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways
JL Slack, K Schooley, TP Bonnert, JL Mitcham, EE Qwarnstrom, JE Sims, ...
Journal of Biological Chemistry 275 (7), 4670-4678, 2000
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