Colin Hughes
Colin Hughes
Professor of Microbiology University of Cambridge, Fellow Trinity College Cambridge
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export
V Koronakis, A Sharff, E Koronakis, B Luisi, C Hughes
Nature 405 (6789), 914-919, 2000
11822000
Substrate‐induced assembly of a contiguous channel for protein export from E.coli: reversible bridging of an inner‐membrane translocase to an outer membrane …
T Thanabalu, E Koronakis, C Hughes, V Koronakis
The EMBO journal 17 (22), 6487-6496, 1998
3741998
Swarming motility
GM Fraser, C Hughes
Current opinion in microbiology 2 (6), 630-635, 1999
3661999
Structure and function of TolC: the bacterial exit duct for proteins and drugs
V Koronakis, J Eswaran, C Hughes
Annual review of biochemistry 73 (1), 467-489, 2004
3492004
Activation of Escherichia coli prohaemolysin to the mature toxin by acyl carrier protein-dependent fatty acylation
JP Issartel, V Koronakis, C Hughes
Nature 351 (6329), 759-761, 1991
3301991
The assembled structure of a complete tripartite bacterial multidrug efflux pump
MF Symmons, E Bokma, E Koronakis, C Hughes, V Koronakis
Proceedings of the National Academy of Sciences 106 (17), 7173-7178, 2009
2852009
Structure of the periplasmic component of a bacterial drug efflux pump
MK Higgins, E Bokma, E Koronakis, C Hughes, V Koronakis
Proceedings of the National Academy of Sciences 101 (27), 9994-9999, 2004
2812004
The secreted hemolysins of Proteus mirabilis, Proteus vulgaris, and Morganella morganii are genetically related to each other and to the alpha-hemolysin of Escherichia coli.
V Koronakis, M Cross, B Senior, E Koronakis, C Hughes
Journal of bacteriology 169 (4), 1509-1515, 1987
2391987
Interactions underlying assembly of the Escherichia coli AcrAB–TolC multidrug efflux system
T Touzé, J Eswaran, E Bokma, E Koronakis, C Hughes, V Koronakis
Molecular microbiology 53 (2), 697-706, 2004
2362004
Isolation and analysis of the C‐terminal signal directing export of Escherichia coli hemolysin protein across both bacterial membranes.
V Koronakis, E Koronakis, C Hughes
The EMBO journal 8 (2), 595-605, 1989
2351989
Co‐ordinate expression of virulence genes during swarm‐cell differentiation and population migration of Proteus mirabilis
C Ariison, HC Lai, C Hughes
Molecular microbiology 6 (12), 1583-1591, 1992
2291992
Acylation of Escherichia coli hemolysin: a unique protein lipidation mechanism underlying toxin function
P Stanley, V Koronakis, C Hughes
Microbiol. Mol. Biol. Rev. 62 (2), 309-333, 1998
2201998
Ability of Proteus mirabilis to invade human urothelial cells is coupled to motility and swarming differentiation.
C Allison, N Coleman, PL Jones, C Hughes
Infection and Immunity 60 (11), 4740-4746, 1992
2131992
RfaH and the ops element, components of a novel system controlling bacterial transcription elongation
MJA Bailey, C Hughes, V Koronakis
Molecular microbiology 26 (5), 845-851, 1997
2081997
Fatty acylation of two internal lysine residues required for the toxic activity of Escherichia coli hemolysin
P Stanley, LC Packman, V Koronakis, C Hughes
Science 266 (5193), 1992-1996, 1994
2001994
Cloning of the chromosomal determinants encoding hemolysin production and mannose-resistant hemagglutination in Escherichia coli.
H Berger, J Hacker, A Juarez, C Hughes, W Goebel
Journal of bacteriology 152 (3), 1241-1247, 1982
1941982
Cloning and characterization of genes involved in production of mannose-resistant, neuraminidase-susceptible (X) fimbriae from a uropathogenic O6: K15: H31 Escherichia coli strain.
J Hacker, G Schmidt, C Hughes, S Knapp, M Marget, W Goebel
Infection and immunity 47 (2), 434-440, 1985
1921985
Transition to the open state of the TolC periplasmic tunnel entrance
C Andersen, E Koronakis, E Bokma, J Eswaran, D Humphreys, C Hughes, ...
Proceedings of the National Academy of Sciences 99 (17), 11103-11108, 2002
1872002
Three's company: component structures bring a closer view of tripartite drug efflux pumps
J Eswaran, E Koronakis, MK Higgins, C Hughes, V Koronakis
Current opinion in structural biology 14 (6), 741-747, 2004
1782004
Substrate‐specific binding of hook‐associated proteins by FlgN and FliT, putative chaperones for flagellum assembly
GM Fraser, JCQ Bennett, C Hughes
Molecular microbiology 32 (3), 569-580, 1999
1781999
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