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John Charles O'Donnell
John Charles O'Donnell
University of Pennsylvania and CMC-VA Medical Center
Verified email at pennmedicine.upenn.edu - Homepage
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Cited by
Cited by
Year
Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria
EN Genda, JG Jackson, AL Sheldon, SF Locke, TM Greco, JC O'Donnell, ...
The Journal of Neuroscience 31 (50), 18275-18288, 2011
2042011
Neuronal activity and glutamate uptake decrease mitochondrial mobility in astrocytes and position mitochondria near glutamate transporters
JG Jackson, JC O'Donnell, H Takano, DA Coulter, MB Robinson
The Journal of Neuroscience 34 (5), 1613-1624, 2014
1502014
Reactivation of brain acetylcholinesterase by monoisonitrosoacetone increases the therapeutic efficacy against nerve agents in guinea pigs
JW Skovira, JC O’Donnell, I Koplovitz, RK Kan, JH McDonough, TM Shih
Chemico-biological interactions 187 (1-3), 318-324, 2010
722010
In vivo reactivation by oximes of inhibited blood, brain and peripheral tissue cholinesterase activity following exposure to nerve agents in guinea pigs
TM Shih, JW Skovira, JC O’Donnell, JH McDonough
Chemico-biological interactions 187 (1-3), 207-214, 2010
662010
Transient Oxygen/Glucose Deprivation Causes a Delayed Loss of Mitochondria and Increases Spontaneous Calcium Signaling in Astrocytic Processes
JC O'Donnell, JG Jackson, MB Robinson
The Journal of Neuroscience 36 (27), 7109-7127, 2016
532016
Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication
TM Shih, JW Skovira, JC O’Donnell, JH McDonough
Journal of molecular neuroscience 40 (1-2), 63-69, 2010
522010
Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose
TM Shih, JW Skovira, JC O’Donnell, JH McDonough
Toxicology mechanisms and methods 19 (6-7), 386-400, 2009
492009
The circadian gene Rev-erbα improves cellular bioenergetics and provides preconditioning for protection against oxidative stress
S Sengupta, G Yang, JC O’Donnell, MD Hinson, SE McCormack, MJ Falk, ...
Free Radical Biology and Medicine 93, 177-189, 2016
462016
Tissue engineered bands of Büngner for accelerated motor and sensory axonal outgrowth
KV Panzer, JC Burrell, KVT Helm, EM Purvis, Q Zhang, AD Le, ...
Frontiers in Bioengineering and Biotechnology, 1227, 2020
422020
Displacing hexokinase from mitochondrial voltage‐dependent anion channel impairs GLT‐1‐mediated glutamate uptake but does not disrupt interactions between GLT‐1 and …
JG Jackson, JC O'Donnell, E Krizman, MB Robinson
Journal of neuroscience research 93 (7), 999-1008, 2015
332015
Central acetylcholinesterase reactivation by oximes improves survival and terminates seizures following nerve agent intoxication
TM Shih, JW Skovira, JC O'Donnell, JH McDonough
ARMY MEDICAL RESEARCH INST OF CHEMICAL DEFENSE ABERDEEN PROVING GROUND MD …, 2009
292009
Challenges and demand for modeling disorders of consciousness following traumatic brain injury
JC O’Donnell, KD Browne, TJ Kilbaugh, HI Chen, J Whyte, DK Cullen
Neuroscience & Biobehavioral Reviews 98, 336-346, 2019
252019
In vivo microdialysis and electroencephalographic activity in freely moving guinea pigs exposed to organophosphorus nerve agents sarin and VX: analysis of acetylcholine and …
JC O’Donnell, JH McDonough, TM Shih
Archives of toxicology 85 (12), 1607-1616, 2011
252011
Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration.
KS Katiyar, CC Winter, WJ Gordián-Vélez, JC O'Donnell, YJ Song, ...
Journal of visualized experiments: JoVE, 2018
212018
Tissue engineering and biomaterial strategies to elicit endogenous neuronal replacement in the brain
EM Purvis, JC O'Donnell, HI Chen, DK Cullen
Frontiers in Neurology 11, 344, 2020
182020
A tissue-engineered rostral migratory stream for directed neuronal replacement
JC O’Donnell, KS Katiyar, KV Panzer, DK Cullen
Neural regeneration research 13 (8), 1327, 2018
152018
Comparison of extracellular striatal acetylcholine and brain seizure activity following acute exposure to the nerve agents cyclosarin and tabun in freely moving guinea pigs
JC O’Donnell, C Acon-Chen, JH McDonough, TM Shih
Toxicology mechanisms and methods 20 (9), 600-608, 2010
122010
Changes in extracellular striatal acetylcholine and brain seizure activity following acute exposure to nerve agents in freely moving guinea pigs
JC O’Donnell, JH McDonough, TM Shih
Toxicology mechanisms and methods 20 (3), 143-152, 2010
122010
Relationships between injury kinematics, neurological recovery, and pathology following concussion
KL Wofford, MR Grovola, DO Adewole, KD Browne, ME Putt, ...
Brain Communications 3 (4), fcab268, 2021
82021
Multimodal Neuromonitoring and Neurocritical Care in Swine to Enhance Translational Relevance in Brain Trauma Research
JC O’Donnell, KD Browne, S Kvint, L Makaron, MR Grovola, S Karandikar, ...
Biomedicines 11 (5), 1336, 2023
72023
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Articles 1–20