| Classification of intrinsically disordered regions and proteins R van der Lee, M Buljan, B Lang, RJ Weatheritt, GW Daughdrill, ... Chemical reviews 114 (13), 6589-6631, 2014 | 1962 | 2014 |
| JASPAR 2020: update of the open-access database of transcription factor binding profiles O Fornes, JA Castro-Mondragon, A Khan, R van der Lee, X Zhang, ... Nucleic acids research 48 (D1), D87-D92, 2020 | 1698 | 2020 |
| JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework A Khan, O Fornes, A Stigliani, M Gheorghe, JA Castro-Mondragon, ... Nucleic acids research 46 (D1), D260-D266, 2018 | 1607 | 2018 |
| Intrinsically disordered proteins: regulation and disease MM Babu, R van der Lee, NS de Groot, J Gsponer Current opinion in structural biology 21 (3), 432-440, 2011 | 668 | 2011 |
| LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants K Westendorf, S Žentelis, L Wang, D Foster, P Vaillancourt, M Wiggin, ... Cell reports 39 (7), 2022 | 341 | 2022 |
| Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution R van der Lee, B Lang, K Kruse, J Gsponer, NS de Groot, MA Huynen, ... Cell reports 8 (6), 1832-1844, 2014 | 226 | 2014 |
| TMEM107 recruits ciliopathy proteins to subdomains of the ciliary transition zone and causes Joubert syndrome NJ Lambacher, AL Bruel, TJP van Dam, K Szymańska, GG Slaats, ... Nature cell biology 18 (1), 122-131, 2016 | 137 | 2016 |
| CiliaCarta: an integrated and validated compendium of ciliary genes TJP Van Dam, J Kennedy, R Van Der Lee, E De Vrieze, KA Wunderlich, ... PloS one 14 (5), e0216705, 2019 | 114 | 2019 |
| The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections M Jaeger, R van der Lee, SC Cheng, MD Johnson, V Kumar, A Ng, ... European Journal of Clinical Microbiology & Infectious Diseases 34 (5), 963-974, 2015 | 89 | 2015 |
| Genome-scale detection of positive selection in nine primates predicts human-virus evolutionary conflicts R Van der Lee, L Wiel, TJP Van Dam, MA Huynen Nucleic Acids Research 45 (18), 10634–10648, 2017 | 76 | 2017 |
| Bi-allelic GOT2 Mutations Cause a Treatable Malate-Aspartate Shuttle-Related Encephalopathy CDM van Karnebeek, RJ Ramos, XY Wen, M Tarailo-Graovac, ... The American Journal of Human Genetics 105 (3), 534-548, 2019 | 57 | 2019 |
| Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease M Sharma, D Leung, M Momenilandi, LCW Jones, L Pacillo, AE James, ... Journal of Experimental Medicine 220 (5), e20221755, 2023 | 42 | 2023 |
| Probabilistic data integration identifies reliable gametocyte-specific proteins and transcripts in malaria parasites L Meerstein-Kessel, R van der Lee, W Stone, K Lanke, DA Baker, P Alano, ... Scientific reports 8 (1), 410, 2018 | 40 | 2018 |
| Deregulated regulators: disease-causing cis variants in transcription factor genes R van Der Lee, S Correard, WW Wasserman Trends in Genetics 36 (7), 523-539, 2020 | 34 | 2020 |
| Integrative genomics-based discovery of novel regulators of the innate antiviral response R van der Lee, Q Feng, MA Langereis, R Ter Horst, R Szklarczyk, ... PLoS computational biology 11 (10), e1004553, 2015 | 23 | 2015 |
| The role of clinical response to treatment in determining pathogenicity of genomic variants JJ Shen, SB Wortmann, L de Boer, LAJ Kluijtmans, MCDG Huigen, J Koch, ... Genetics in Medicine 23 (3), 581-585, 2021 | 18 | 2021 |
| Transcriptome analysis of complex I-deficient patients reveals distinct expression programs for subunits and assembly factors of the oxidative phosphorylation system R van der Lee, R Szklarczyk, J Smeitink, HJM Smeets, MA Huynen, ... BMC genomics 16, 1-13, 2015 | 14 | 2015 |
| De novo stop-loss variants in CLDN11 cause hypomyelinating leukodystrophy KM Riedhammer, S Stockler, R Ploski, M Wenzel, B Adis-Dutschmann, ... Brain 144 (2), 411-419, 2021 | 13 | 2021 |
| Adult GAMT deficiency: A literature review and report of two siblings BP Modi, HN Khan, R van der Lee, M Wasim, CA Haaxma, PA Richmond, ... Molecular Genetics and Metabolism Reports 27, 100761, 2021 | 10 | 2021 |
| Curation and bioinformatic analysis of strabismus genes supports functional heterogeneity and proposes candidate genes with connections to RASopathies XC Ye, R van der Lee, WW Wasserman Gene 697, 213-226, 2019 | 7 | 2019 |
Wyeth WassermanProfessor of Medical Genetics, University of British ColumbiaVerified email at cmmt.ubc.ca
