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Scott Donaldson
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Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind …
HGM Heijerman, EF McKone, DG Downey, E Van Braeckel, SM Rowe, ...
The Lancet 394 (10212), 1940-1948, 2019
9802019
Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTR Mutation
FJ Accurso, SM Rowe, JP Clancy, MP Boyle, JM Dunitz, PR Durie, ...
New England Journal of Medicine 363 (21), 1991-2003, 2010
9072010
Mucus clearance and lung function in cystic fibrosis with hypertonic saline
SH Donaldson, WD Bennett, KL Zeman, MR Knowles, R Tarran, ...
New England Journal of Medicine 354 (3), 241-250, 2006
8452006
COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study
VJ Hall, S Foulkes, A Saei, N Andrews, B Oguti, A Charlett, E Wellington, ...
The Lancet 397 (10286), 1725-1735, 2021
7542021
SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN)
VJ Hall, S Foulkes, A Charlett, A Atti, EJM Monk, R Simmons, E Wellington, ...
The Lancet 397 (10283), 1459-1469, 2021
6652021
Results of a phase IIa study of VX-809, an investigational CFTR corrector compound, in subjects with cystic fibrosis homozygous for the F508del-CFTR mutation
JP Clancy, SM Rowe, FJ Accurso, ML Aitken, RS Amin, MA Ashlock, ...
Thorax 67 (1), 12-18, 2012
6482012
Clinical mechanism of the cystic fibrosis transmembrane conductance regulator potentiator ivacaftor in G551D-mediated cystic fibrosis
SM Rowe, SL Heltshe, T Gonska, SH Donaldson, D Borowitz, D Gelfond, ...
American journal of respiratory and critical care medicine 190 (2), 175-184, 2014
5192014
Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure
AG Henderson, C Ehre, B Button, LH Abdullah, LH Cai, MW Leigh, ...
The Journal of clinical investigation 124 (7), 3047-3060, 2014
3392014
Regulation of the epithelial sodium channel by serine proteases in human airways
SH Donaldson, A Hirsh, DC Li, G Holloway, J Chao, RC Boucher, ...
Journal of Biological Chemistry 277 (10), 8338-8345, 2002
3192002
Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia
R Tarran, L Trout, SH Donaldson, RC Boucher
The Journal of general physiology 127 (5), 591-604, 2006
2542006
CFTR modulator theratyping: Current status, gaps and future directions
JP Clancy, CU Cotton, SH Donaldson, GM Solomon, DR VanDevanter, ...
Journal of Cystic Fibrosis 18 (1), 22-34, 2019
2412019
Cystic fibrosis lung disease starts in the small airways: can we treat it more effectively?
HAWM Tiddens, SH Donaldson, M Rosenfeld, PD Paré
Pediatric pulmonology 45 (2), 107-117, 2010
2202010
Sodium channels and cystic fibrosis
SH Donaldson, RC Boucher
Chest 132 (5), 1631-1636, 2007
2042007
Tezacaftor/Ivacaftor in Subjects with Cystic Fibrosis and F508del/F508del-CFTR or F508del/G551D-CFTR
SH Donaldson, JM Pilewski, M Griese, J Cooke, L Viswanathan, E Tullis, ...
American journal of respiratory and critical care medicine 197 (2), 214-224, 2018
2022018
A biophysical basis for mucus solids concentration as a candidate biomarker for airways disease
DB Hill, PA Vasquez, J Mellnik, SA McKinley, A Vose, F Mu, ...
PloS one 9 (2), e87681, 2014
1972014
SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage
A Garcia-Caballero, JE Rasmussen, E Gaillard, MJ Watson, JC Olsen, ...
Proceedings of the national academy of sciences 106 (27), 11412-11417, 2009
1962009
Clinical effectiveness of elexacaftor/tezacaftor/ivacaftor in people with cystic fibrosis: a clinical trial
DP Nichols, AC Paynter, SL Heltshe, SH Donaldson, CA Frederick, ...
American journal of respiratory and critical care medicine 205 (5), 529-539, 2022
1862022
Update on pathogenesis of cystic fibrosis lung disease
SH Donaldson, RC Boucher
Current opinion in pulmonary medicine 9 (6), 486-491, 2003
1842003
Basal nucleotide levels, release, and metabolism in normal and cystic fibrosis airways
SH Donaldson, ER Lazarowski, M Picher, MR Knowles, MJ Stutts, ...
Molecular Medicine 6, 969-982, 2000
1222000
Extracellular purines are biomarkers of neutrophilic airway inflammation
CR Esther, NE Alexis, ML Clas, ER Lazarowski, SH Donaldson, ...
European Respiratory Journal 31 (5), 949-956, 2008
1062008
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Articles 1–20