Laura Gasparini
Laura Gasparini
Abbvie Deutschland GmbH & Co KG
Verified email at
TitleCited byYear
Stimulation of β-amyloid precursor protein trafficking by insulin reduces intraneuronal β-amyloid and requires mitogen-activated protein kinase signaling
L Gasparini, GK Gouras, R Wang, RS Gross, MF Beal, P Greengard, H Xu
Journal of Neuroscience 21 (8), 2561-2570, 2001
Does insulin dysfunction play a role in Alzheimer's disease?
L Gasparini, WJ Netzer, P Greengard, H Xu
Trends in pharmacological sciences 23 (6), 288-293, 2002
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
Y Chen, K Zhou, R Wang, Y Liu, YD Kwak, T Ma, RC Thompson, Y Zhao, ...
Proceedings of the National Academy of Sciences 106 (10), 3907-3912, 2009
Potential roles of insulin and IGF-1 in Alzheimer's disease
L Gasparini, H Xu
Trends in neurosciences 26 (8), 404-406, 2003
Non‐steroidal anti‐inflammatory drugs (NSAIDs) in Alzheimer's disease: old and new mechanisms of action
L Gasparini, E Ongini, G Wenk
Journal of neurochemistry 91 (3), 521-536, 2004
Characterization of a Presenilin-mediated Amyloid Precursor Protein Carboxyl-terminal Fragment γ EVIDENCE FOR DISTINCT MECHANISMS INVOLVED IN γ-SECRETASE PROCESSING OF THE APP …
C Yu, SH Kim, T Ikeuchi, H Xu, L Gasparini, R Wang, SS Sisodia
Journal of Biological Chemistry 276 (47), 43756-43760, 2001
Interaction of tau protein with the dynactin complex
E Magnani, J Fan, L Gasparini, M Golding, M Williams, G Schiavo, ...
The EMBO journal 26 (21), 4546-4554, 2007
Peripheral markers in testing pathophysiological hypotheses and diagnosing Alzheimer's disease
L Gasparini, M Racchi, G Binetti, M Trabucchi, SB Solerte, D Alkon, ...
The FASEB journal 12 (1), 17-34, 1998
Communication breaks-Down: from neurodevelopment defects to cognitive disabilities in Down syndrome
A Contestabile, F Benfenati, L Gasparini
Progress in neurobiology 91 (1), 1-22, 2010
Modulation of β‐amyloid metabolism by non‐steroidal anti‐inflammatory drugs in neuronal cell cultures
L Gasparini, L Rusconi, H Xu, P Del Soldato, E Ongini
Journal of neurochemistry 88 (2), 337-348, 2004
Lithium rescues synaptic plasticity and memory in Down syndrome mice
A Contestabile, B Greco, D Ghezzi, V Tucci, F Benfenati, L Gasparini
The Journal of Clinical Investigation 123 (1), 348, 2013
Attenuation of chronic neuroinflammation by a nitric oxide‐releasing derivative of the antioxidant ferulic acid
GL Wenk, K McGann‐Gramling, B Hauss‐Wegrzyniak, D Ronchetti, ...
Journal of neurochemistry 89 (2), 484-493, 2004
Activity of flurbiprofen and chemically related anti-inflammatory drugs in models of Alzheimer's disease
L Gasparini, E Ongini, D Wilcock, D Morgan
Brain research reviews 48 (2), 400-408, 2005
A large genomic deletion leads to enhancer adoption by the lamin B1 gene: a second path to autosomal dominant adult-onset demyelinating leukodystrophy (ADLD)
E Giorgio, D Robyr, M Spielmann, E Ferrero, E Di Gregorio, D Imperiale, ...
Human molecular genetics 24 (11), 3143-3154, 2015
Presenilin 1 protein directly interacts with Bcl-2
A Alberici, D Moratto, L Benussi, L Gasparini, R Ghidoni, LB Gatta, ...
Journal of Biological Chemistry 274 (43), 30764-30769, 1999
Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells
L Gasparini, M Racchi, L Benussi, D Curti, G Binetti, A Bianchetti, ...
Neuroscience letters 231 (2), 113-117, 1997
Tau inclusions in retinal ganglion cells of human P301S tau transgenic mice: effects on axonal viability
L Gasparini, RA Crowther, KR Martin, N Berg, M Coleman, M Goedert, ...
Neurobiology of aging 32 (3), 419-433, 2011
A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface
JY Leem, CA Saura, C Pietrzik, J Christianson, C Wanamaker, LST King, ...
Neurobiology of disease 11 (1), 64-82, 2002
Nuclear receptor peroxisome proliferator‐activated receptor‐γ is activated in rat microglial cells by the anti‐inflammatory drug HCT1026, a derivative of flurbiprofen
A Bernardo, MA Ajmone‐Cat, L Gasparini, E Ongini, L Minghetti
Journal of neurochemistry 92 (4), 895-903, 2005
Frontotemporal dementia with tau pathology
L Gasparini, B Terni, MG Spillantini
Neurodegenerative Diseases 4 (2-3), 236-253, 2007
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