Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism RL Krauth-Siegel, MA Comini Biochimica et Biophysica Acta (BBA)-General Subjects 1780 (11), 1236-1248, 2008 | 488 | 2008 |
Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification F Irigoín, L Cibils, MA Comini, SR Wilkinson, L Flohé, R Radi Free Radical Biology and Medicine 45 (6), 733-742, 2008 | 198 | 2008 |
Identification of novel bacterial plasminogen‐binding proteins in the human pathogen Mycobacterium tuberculosis W Xolalpa, AJ Vallecillo, M Lara, G Mendoza‐Hernandez, M Comini, ... Proteomics 7 (18), 3332-3341, 2007 | 151 | 2007 |
Validation of Trypanosoma brucei trypanothione synthetase as drug target MA Comini, SA Guerrero, S Haile, U Menge, H Lünsdorf, L Flohé Free Radical Biology and Medicine 36 (10), 1289-1302, 2004 | 144 | 2004 |
Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids B Manta, M Comini, A Medeiros, M Hugo, M Trujillo, R Radi Biochimica et Biophysica Acta (BBA)-General Subjects 1830 (5), 3199-3216, 2013 | 143 | 2013 |
Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes MA Comini, RL Krauth-Siegel, L Flohé Biochemical Journal 402 (1), 43-49, 2007 | 114 | 2007 |
New organoruthenium complexes with bioactive thiosemicarbazones as co-ligands: potential anti-trypanosomal agents B Demoro, C Sarniguet, R Sánchez-Delgado, M Rossi, D Liebowitz, ... Dalton Transactions 41 (5), 1534-1543, 2012 | 106 | 2012 |
The trypanothione system LR Krauth-Siegel, MA Comini, T Schlecker Peroxiredoxin Systems: Structures and Functions, 231-251, 2007 | 99 | 2007 |
Measurement and meaning of cellular thiol: disufhide redox status MA Comini Free radical research 50 (2), 246-271, 2016 | 88 | 2016 |
Evaluation of the diagnostic value of measuring IgG, IgM and IgA antibodies to the recombinant 16-kilodalton antigen of Mycobacterium tuberculosis in childhood tuberculosis S Imaz M, A Comini M, E Zerbini, D Sequeira M, J Spoletti M, A Etchart A, ... The International Journal of Tuberculosis and Lung Disease 5 (11), 1036-1043, 2001 | 85 | 2001 |
Monothiol glutaredoxin-1 is an essential iron-sulfur protein in the mitochondrion of African trypanosomes MA Comini, J Rettig, N Dirdjaja, EM Hanschmann, C Berndt, ... Journal of biological chemistry 283 (41), 27785-27798, 2008 | 81 | 2008 |
Trypanothione synthesis in Crithidia revisited M Comini, U Menge, J Wissing, L Flohé Journal of Biological Chemistry 280 (8), 6850-6860, 2005 | 72 | 2005 |
Identification of novel chemical scaffolds inhibiting trypanothione synthetase from pathogenic trypanosomatids D Benítez, A Medeiros, L Fiestas, EA Panozzo-Zenere, F Maiwald, ... PLoS neglected tropical diseases 10 (4), e0004617, 2016 | 67 | 2016 |
Oxidovanadium (IV) and dioxidovanadium (V) complexes of tridentate salicylaldehyde semicarbazones: searching for prospective antitrypanosomal agents M Fernández, L Becco, I Correia, J Benítez, OE Piro, GA Echeverria, ... Journal of Inorganic Biochemistry 127, 150-160, 2013 | 67 | 2013 |
Catalytic mechanism of the glutathione peroxidase-type tryparedoxin peroxidase of Trypanosoma brucei T Schlecker, MA Comini, J Melchers, T Ruppert, RL Krauth-Siegel Biochemical Journal 405 (3), 445-454, 2007 | 67 | 2007 |
Biosynthesis of trypanothione in Trypanosoma brucei brucei M Comini, U Menge, L Flohé Walter de Gruyter 384 (4), 653-656, 2003 | 61 | 2003 |
Determination of acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection F Sardi, B Manta, S Portillo-Ledesma, B Knoops, MA Comini, ... Analytical Biochemistry 435 (1), 74-82, 2013 | 60 | 2013 |
Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum AF Sousa, AG Gomes-Alves, D Benítez, MA Comini, L Flohé, T Jaeger, ... Free Radical Biology and Medicine 73, 229-238, 2014 | 57 | 2014 |
The mycobacterial thioredoxin peroxidase can act as a one-cysteine peroxiredoxin M Trujillo, PL Mauri, L Benazzi, M Comini, A De Palma, L Flohé, R Radi, ... Journal of biological chemistry 281 (29), 20555-20566, 2006 | 55 | 2006 |
Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1 M Filser, MA Comini, MM Molina-Navarro, N Dirdjaja, E Herrero, ... Walter de Gruyter 389 (1), 21-32, 2008 | 54 | 2008 |