| Combined treatment with a BACE inhibitor and anti-Aβ antibody gantenerumab enhances amyloid reduction in APPLondon mice H Jacobsen, L Ozmen, A Caruso, R Narquizian, H Hilpert, B Jacobsen, ... Journal of Neuroscience 34 (35), 11621-11630, 2014 | 113 | 2014 |
| Application of PBPK modeling to predict human intestinal metabolism of CYP3A substrates–an evaluation and case study using GastroPlus™ AT Heikkinen, G Baneyx, A Caruso, N Parrott European journal of pharmaceutical sciences 47 (2), 375-386, 2012 | 80 | 2012 |
| Recent developments in using mechanistic cardiac modelling for drug safety evaluation MR Davies, K Wang, GR Mirams, A Caruso, D Noble, A Walz, T Lavé, ... Drug discovery today 21 (6), 924-938, 2016 | 76 | 2016 |
| Ocular half-life of intravitreal biologics in humans and other species: meta-analysis and model-based prediction A Caruso, M Füth, R Alvarez-Sánchez, S Belli, C Diack, KF Maass, ... Molecular Pharmaceutics 17 (2), 695-709, 2019 | 45 | 2019 |
| Translational PK/PD modeling for cardiovascular safety assessment of drug candidates: methods and examples in drug development A Caruso, N Frances, C Meille, A Greiter-Wilke, A Hillebrecht, T Lavé Journal of pharmacological and toxicological methods 70 (1), 73-85, 2014 | 39 | 2014 |
| Theoretical insights into the retinal dynamics of vascular endothelial growth factor in patients treated with ranibizumab, based on an ocular pharmacokinetic/pharmacodynamic model LA Hutton-Smith, EA Gaffney, HM Byrne, A Caruso, PK Maini, NA Mazer Molecular pharmaceutics 15 (7), 2770-2784, 2018 | 34 | 2018 |
| Translational PK/PD modeling to increase probability of success in drug discovery and early development T Lavé, A Caruso, N Parrott, A Walz Drug Discovery Today: Technologies 21, 27-34, 2016 | 31 | 2016 |
| PK/PD assessment in CNS drug discovery: Prediction of CSF concentration in rodents for P-glycoprotein substrates and application to in vivo potency estimation A Caruso, R Alvarez-Sánchez, A Hillebrecht, A Poirier, F Schuler, T Lavé, ... Biochemical Pharmacology 85 (11), 1684-1699, 2013 | 30 | 2013 |
| Control of drug administration during monitored anesthesia care ALG Caruso, TW Bouillon, PM Schumacher, E Zanderigo, M Morari IEEE transactions on automation science and engineering 6 (2), 256-264, 2009 | 21 | 2009 |
| Ocular pharmacokinetics of intravitreally injected protein therapeutics: comparison among standard-of-care formats P Jakubiak, R Alvarez-Sánchez, M Fueth, O Broders, H Kettenberger, ... Molecular Pharmaceutics 18 (6), 2208-2217, 2021 | 14 | 2021 |
| The dynamics of Aβ distribution after γ-secretase inhibitor treatment, as determined by experimental and modelling approaches in a wild type rat LM Tai, H Jacobsen, L Ozmen, A Flohr, R Jakob-Roetne, A Caruso, ... Journal of pharmacokinetics and pharmacodynamics 39, 227-237, 2012 | 12 | 2012 |
| Model-based heart rate control during robot-assisted gait training A Koenig, A Caruso, M Bolliger, L Somaini, X Omlin, M Morari, R Riener 2011 IEEE International Conference on Robotics and Automation, 4151-4156, 2011 | 12 | 2011 |
| Drug-induced respiratory depression: an integrated model of drug effects on the hypercapnic and hypoxic drive ALG Caruso, TW Bouillon, PM Schumacher, M Luginbuhl, M Morari 2007 29th Annual International Conference of the IEEE Engineering in …, 2007 | 12 | 2007 |
| On the modeling of drug induced respiratory depression in the non-steady-state ALG Caruso, TW Bouillon, PM Schumacher, M Morari 2008 30th Annual International Conference of the IEEE Engineering in …, 2008 | 11 | 2008 |
| System for Controlling Administration of Anaesthesia T Bouillon, A Caruso, M Luginbühl, M Morari, PM Schumacher, ... US Patent App. 12/305,806, 2010 | 10 | 2010 |
| Understanding the half-life extension of intravitreally administered antibodies binding to ocular albumin S Hauri, P Jakubiak, M Fueth, S Dengl, S Belli, R Alvarez-Sánchez, ... Pharmaceutics 12 (9), 810, 2020 | 6 | 2020 |
| Model predictive control for propofol sedation ALG Caruso, M Morari World Congress on Medical Physics and Biomedical Engineering, September 7-12 …, 2009 | 6 | 2009 |
| Modeling the activation of the alternative complement pathway and its effects on hemolysis in health and disease A Caruso, J Vollmer, M Machacek, E Kortvely PLoS Computational Biology 16 (10), e1008139, 2020 | 5 | 2020 |
| Personalized drug dosing through modeling and feedback ALG Caruso ETH Zurich, 2009 | 4 | 2009 |
| Dynamic Properties of a New Transcutaneous CO2 Sensor: Fast Enough for Early Detection of Apnea? PM Schumacher, ALG Caruso, V Hartwich, M Luginbühl, TW Bouillon Annual Meeting of the American Society of Anesthesiologists (ASA) 2006, 2006 | 4 | 2006 |
