Chemical synthesis of natural product peptides: coupling methods for the incorporation of noncoded amino acids into peptides JM Humphrey, AR Chamberlin Chemical Reviews 97 (6), 2243-2266, 1997 | 1350 | 1997 |
Increasing rates of reaction: microwave-assisted organic synthesis for combinatorial chemistry A Lew, PO Krutzik, ME Hart, AR Chamberlin Journal of combinatorial chemistry 4 (2), 95-105, 2001 | 587 | 2001 |
Biosynthetic site-specific incorporation of a non-natural amino acid into a polypeptide JD Bain, ES Diala, CG Glabe, TA Dix, AR Chamberlin Journal of the American Chemical Society 111 (20), 8013-8014, 1989 | 494 | 1989 |
Ribosome-mediated incorporation of a non-standard amino acid into a peptide through expansion of the genetic code JD Bain, C Switzer, R Chamberlin, SA Benner Nature 356 (6369), 537-539, 1992 | 410 | 1992 |
Conformationally defined neurotransmitter analogs. Selective inhibition of glutamate uptake by one pyrrolidine-2, 4-dicarboxylate diastereomer RJ Bridges, MS Stanley, MW Anderson, CW Cotman, AR Chamberlin Journal of medicinal chemistry 34 (2), 717-725, 1991 | 395 | 1991 |
Congener-independent immunoassay for microcystins and nodularins WJ Fischer, I Garthwaite, CO Miles, KM Ross, JB Aggen, AR Chamberlin, ... Environmental science & technology 35 (24), 4849-4856, 2001 | 328 | 2001 |
Regulation of protein phosphatase-1 JB Aggen, AC Nairn, R Chamberlin Chemistry & biology 7 (1), R13-R23, 2000 | 253 | 2000 |
Vinyllithium reagents from arenesulfonylhydrazones AR Chamberlin, JE Stemke, FT Bond The Journal of Organic Chemistry 43 (1), 147-154, 1978 | 238 | 1978 |
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53 CD Wassman, R Baronio, Ö Demir, BD Wallentine, CK Chen, LV Hall, ... Nature communications 4 (1), 1407, 2013 | 233 | 2013 |
Inhibition of the Ser-Thr phosphatases PP1 and PP2A by naturally occurring toxins JE Sheppeck II, CM Gauss, AR Chamberlin Bioorganic & medicinal chemistry 5 (9), 1739-1750, 1997 | 193 | 1997 |
Modeling chemical reactivity. 7. The effect of a change in rate-limiting step on the stereoselectivity of electrophilic addition to allylic alcohols and related chiral alkenes AR Chamberlin, RL Mulholland Jr, SD Kahn, WJ Hehre Journal of the American Chemical Society 109 (3), 672-677, 1987 | 190 | 1987 |
Enantioselective preparation of. beta.-alkyl-. gamma.-butyrolactones from functionalized ketene dithioacetals SSC Koch, AR Chamberlin The Journal of Organic Chemistry 58 (10), 2725-2737, 1993 | 169 | 1993 |
Site-specific incorporation of nonnatural residues during in vitro protein biosynthesis with semi-synthetic aminoacyl-tRNAs JD Bain, ES Diala, CG Glabe, DA Wacker, MH Lyttle, TA Dix, ... Biochemistry 30 (22), 5411-5421, 1991 | 159 | 1991 |
Modeling chemical reactivity. 4. Regiochemistry and stereochemistry of electrophilic additions to allylic double bonds SD Kahn, CF Pau, AR Chamberlin, WJ Hehre Journal of the American Chemical Society 109 (3), 650-663, 1987 | 158 | 1987 |
Synthesis of optically active pyrrolizidinediols:(+)-heliotridine AR Chamberlin, JYL Chung Journal of the American Chemical Society 105 (11), 3653-3656, 1983 | 155 | 1983 |
Total synthesis of maytansine EJ Corey, LO Weigel, AR Chamberlin, H Cho, DH Hua Journal of the American Chemical Society 102 (21), 6613-6615, 1980 | 155 | 1980 |
Iodocyclization of allylic alcohol derivatives containing internal nucleophiles. Control of stereoselectivity by substituents in the acyclic precursors AR Chamberlin, M Dezube, P Dussault, MC McMills Journal of the American Chemical Society 105 (18), 5819-5825, 1983 | 151 | 1983 |
Modified norcantharidins: synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity ME Hart, AR Chamberlin, C Walkom, JA Sakoff, A McCluskey Bioorganic & medicinal chemistry letters 14 (8), 1969-1973, 2004 | 150 | 2004 |
Synthesis and pharmacological in vitro and in vivo profile of 3-oxo-1, 1-diphenyl-tetrahydro-oxazolo [3, 4-a] pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68), a … N Okamura, SA Habay, J Zeng, AR Chamberlin, RK Reinscheid Journal of pharmacology and experimental therapeutics 325 (3), 893-901, 2008 | 145 | 2008 |
A pharmacological review of competitive inhibitors and substrates of high-affinity, sodium-dependent glutamate transport in the central nervous system RJ Bridges, MP Kavanaugh, AR Chamberlin Current pharmaceutical design 5 (5), 363-380, 1999 | 145 | 1999 |