Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis D Richardson, RG Pearson, N Kurian, ML Latif, MJ Garle, DA Barrett, ... Arthritis research & therapy 10, 1-14, 2008 | 392 | 2008 |
Macrophage phagocytosis cracking the defect code in COPD J Jubrail, N Kurian, F Niedergang biomedical journal 40 (6), 305-312, 2017 | 50 | 2017 |
The development of AZD7624 for prevention of exacerbations in COPD: a randomized controlled trial NR Patel, DM Cunoosamy, M Fagerås, Z Taib, S Asimus, ... International journal of chronic obstructive pulmonary disease, 1009-1019, 2018 | 46 | 2018 |
Osimertinib + Savolitinib to Overcome Acquired MET-Mediated Resistance in Epidermal Growth Factor Receptor–Mutated, MET-Amplified Non–Small Cell Lung … RJ Hartmaier, AA Markovets, MJ Ahn, LV Sequist, JY Han, BC Cho, ... Cancer discovery 13 (1), 98-113, 2023 | 42 | 2023 |
The rheumatoid synovial environment alters fatty acid metabolism in human monocytes and enhances CCL20 secretion LC Rodgers, J Cole, KM Rattigan, MP Barrett, N Kurian, IB McInnes, ... Rheumatology 59 (4), 869-878, 2020 | 29 | 2020 |
Eosinophil-derived neurotoxin: A biologically and analytically attractive asthma biomarker B Rutten, S Young, M Rhedin, M Olsson, N Kurian, F Syed, A Beech, ... PLoS One 16 (2), e0246627, 2021 | 25 | 2021 |
Arpin is critical for phagocytosis in macrophages and is targeted by human rhinovirus J Jubrail, K Africano‐Gomez, F Herit, A Mularski, P Bourdoncle, L Oberg, ... EMBO reports 21 (1), e47963, 2020 | 20 | 2020 |
Full and partial agonists of muscarinic M3 receptors reveal single and oscillatory Ca2+ responses by β2-adrenoceptors N Kurian, CJ Hall, GF Wilkinson, M Sullivan, AB Tobin, GB Willars Journal of Pharmacology and Experimental Therapeutics 330 (2), 502-512, 2009 | 20 | 2009 |
MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling E Baturcam, S Vollmer, H Schlüter, RA Maciewicz, N Kurian, O Vaarala, ... Cell Communication and Signaling 17, 1-19, 2019 | 16 | 2019 |
Lentiviral delivery of a vesicular glutamate transporter 1 (VGLUT1)-targeting short hairpin RNA vector into the mouse hippocampus impairs cognition MV King, N Kurian, S Qin, N Papadopoulou, BHC Westerink, TI Cremers, ... Neuropsychopharmacology 39 (2), 464-476, 2014 | 15 | 2014 |
Dual role for a MEK inhibitor as a modulator of inflammation and host defense mechanisms with potential therapeutic application in COPD N Kurian, TS Cohen, L Öberg, E De Zan, G Skogberg, S Vollmer, ... International Journal of Chronic Obstructive Pulmonary Disease, 2611-2624, 2019 | 14 | 2019 |
Altered regulation and expression of genes by BET family of proteins in COPD patients R Malhotra, N Kurian, XH Zhou, F Jiang, S Monkley, A DeMicco, ... PLoS One 12 (3), e0173115, 2017 | 12 | 2017 |
HRV16 impairs macrophages cytokine response to a secondary bacterial trigger J Jubrail, K Africano-Gomez, F Herit, E Baturcam, G Mayer, ... Frontiers in Immunology 9, 2908, 2018 | 10 | 2018 |
A Novel Inhaled Non-Steroidal Modulator Of Inflammation For The Control Of Asthma; Azd7594 KE C. K. Mardh , W. Russell , M. Gustavsson , N. Kurian , A.-H. Jansson , A ... Am J Respir Crit Care Med 193, A1329, 2016 | 7* | 2016 |
Abstract CT127: Tumor response and MET-detection methods exploratory biomarker analysis of Part B of the Ph 1b TATTON study R Hartmaier, JY Han, BC Cho, A Markovets, N Kurian, M Cantarini, ... Cancer Research 81 (13_Supplement), CT127-CT127, 2021 | 4 | 2021 |
DUETTE: A randomized phase II study to assess a second maintenance treatment with olaparib (ola) or ola+ ceralasertib (cer), in patients (pts) with platinum-sensitive relapsed … AM Oza, A Pierce, A Lau, N Kurian, G Parr, SH Lao-Sirieix, MLW Ah-See, ... Journal of Clinical Oncology 38 (15_suppl), TPS6104-TPS6104, 2020 | 3 | 2020 |
Differential sensitivity of subsets of monocyte-derived macrophages to apoptosis; its impact on lung inflammation N Kurian, D Cunoosamy European Respiratory Journal 44 (Suppl 58), P1470, 2014 | 2 | 2014 |
PLANETTE: A modular phase IIa multicenter open-label study evaluating the ATR inhibitor ceralasertib (AZD6738) in ATM mutant advanced solid tumors. W Abida, E Sanay, N Lukashchuk, A Pierce, W de Graaf, A Lau, ... Journal of Clinical Oncology 39 (6_suppl), TPS189-TPS189, 2021 | 1 | 2021 |
Eosinophil-derived neurotoxin (EDN) in healthy and asthmatic volunteers B Rutten, S Young, N Kurian, R Hidi, G Hughes European Respiratory Journal 52 (suppl 62), 2018 | 1 | 2018 |
Human rhinovirus 16 infection of human macrophages significantly impairs their phagocytic and regulatory functions: implications in understanding chronic inflammatory lung disease J Jubrail, KA Gomez, PR Burgel, G Mayer, N Kurian, F Niedergang European Respiratory Journal 50 (suppl 61), 2017 | 1 | 2017 |