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Carla Mellough
Carla Mellough
Brian King Research Fellow, Lions Eye Institute, COVS, UWA
Verified email at lei.org.au
Title
Cited by
Cited by
Year
Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells
CB Mellough, E Sernagor, I Moreno-Gimeno, DHW Steel, M Lako
Stem cells 30 (4), 673-686, 2012
1962012
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
A Buskin, L Zhu, V Chichagova, B Basu, S Mozaffari-Jovin, D Dolan, ...
Nature communications 9 (1), 4234, 2018
1732018
3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development
NC Hunt, D Hallam, A Karimi, CB Mellough, J Chen, DHW Steel, M Lako
Acta biomaterialia 49, 329-343, 2017
1522017
IGF-1 signaling plays an important role in the formation of three-dimensional laminated neural retina and other ocular structures from human embryonic stem cells
CB Mellough, J Collin, M Khazim, K White, E Sernagor, DHW Steel, ...
Stem cells 33 (8), 2416-2430, 2015
1492015
Gene therapy and transplantation in CNS repair: the visual system
AR Harvey, Y Hu, SG Leaver, CB Mellough, K Park, J Verhaagen, ...
Progress in retinal and eye research 25 (5), 449-489, 2006
1472006
Retinal pigment epithelium and age‐related macular degeneration: a review of major disease mechanisms
S Somasundaran, IJ Constable, CB Mellough, LS Carvalho
Clinical & Experimental Ophthalmology 48 (8), 1043-1056, 2020
892020
An integrated transcriptional analysis of the developing human retina
CB Mellough, R Bauer, J Collin, B Dorgau, D Zerti, DWP Dolan, CM Jones, ...
Development 146 (2), dev169474, 2019
832019
Systematic comparison of retinal organoid differentiation from human pluripotent stem cells reveals stage specific, cell line, and methodological differences
CB Mellough, J Collin, R Queen, G Hilgen, B Dorgau, D Zerti, ...
Stem cells translational medicine 8 (7), 694-706, 2019
812019
An induced pluripotent stem cell patient specific model of complement factor H (Y402H) polymorphism displays characteristic features of age-related macular degeneration and …
D Hallam, J Collin, S Bojic, V Chichagova, A Buskin, Y Xu, L Lafage, ...
Stem Cells 35 (11), 2305-2320, 2017
672017
CRX expression in pluripotent stem cell-derived photoreceptors marks a transplantable subpopulation of early cones
J Collin, D Zerti, R Queen, T Santos-Ferreira, R Bauer, J Coxhead, ...
Stem Cells 37 (5), 609-622, 2019
632019
Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models
R Megaw, H Abu-Arafeh, M Jungnickel, C Mellough, C Gurniak, W Witke, ...
Nature Communications 8 (1), 271, 2017
612017
Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells
CB Mellough, Q Cui, KL Spalding, NA Symons, MA Pollett, EY Snyder, ...
Experimental neurology 186 (1), 6-19, 2004
592004
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular
OG Izuogu, AA Alhasan, C Mellough, J Collin, R Gallon, J Hyslop, ...
BMC genomics 19, 1-18, 2018
492018
Treatment of adult neural progenitor cells prior to transplantation affects graft survival and integration in a neonatal and adult rat model of selective retinal ganglion cell …
CB Mellough, Q Cui, AR Harvey
Restorative neurology and neuroscience 25 (2), 177-190, 2007
442007
Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 …
M Felemban, B Dorgau, NC Hunt, D Hallam, D Zerti, R Bauer, Y Ding, ...
Acta biomaterialia 74, 207-221, 2018
412018
Using zinc finger nuclease technology to generate CRX-reporter human embryonic stem cells as a tool to identify and study the emergence of photoreceptors precursors during …
J Collin, CB Mellough, B Dorgau, S Przyborski, I Moreno-Gimeno, M Lako
Stem Cells 34 (2), 311-321, 2016
362016
Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation
B Dorgau, M Felemban, A Sharpe, R Bauer, D Hallam, DH Steel, ...
Cell death & disease 9 (6), 615, 2018
242018
Lab generated retina: Realizing the dream
CB Mellough, J Collin, E Sernagor, NK Wride, DHW Steel, M Lako
Visual neuroscience 31 (4-5), 317-332, 2014
232014
A review of gene, drug and cell-based therapies for Usher syndrome
LS French, CB Mellough, FK Chen, LS Carvalho
Frontiers in Cellular Neuroscience 14, 183, 2020
222020
Genetic basis of inherited macular dystrophies and implications for stem cell therapy
CB Mellough, DHW Steel, M Lako
Stem cells 27 (11), 2833-2845, 2009
152009
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