Follow
Lucy Kate Ladefoged
Lucy Kate Ladefoged
Postdoc, Computational Chemistry, Dept. of Biomedicine and Dept. of Chemistry, Aarhus University
Verified email at inano.au.dk
Title
Cited by
Cited by
Year
A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition
T Zeppelin, LK Ladefoged, S Sinning, X Periole, B Schiøtt
PLoS computational biology 14 (1), e1005907, 2018
842018
Monoamine transporters: insights from molecular dynamics simulations
J Grouleff, LK Ladefoged, H Koldsø, B Schiøtt
Frontiers in pharmacology 6, 159328, 2015
782015
Binding of the multimodal antidepressant drug vortioxetine to the human serotonin transporter
J Andersen, LK Ladefoged, D Wang, TNB Kristensen, B Bang-Andersen, ...
ACS chemical neuroscience 6 (11), 1892-1900, 2015
272015
Binding-Induced Fluorescence of Serotonin Transporter Ligands: A Spectroscopic and Structural Study of 4-(4-(Dimethylamino)phenyl)-1-methylpyridinium (APP+) and APP …
JN Wilson, LK Ladefoged, WM Babinchak, B Schiøtt
ACS chemical neuroscience 5 (4), 296-304, 2014
242014
Interrogating the molecular basis for substrate recognition in serotonin and dopamine transporters with high-affinity substrate-based bivalent ligands
J Andersen, LK Ladefoged, TNB Kristensen, L Munro, J Grouleff, ...
ACS chemical neuroscience 7 (10), 1406-1417, 2016
212016
Modeling and mutational analysis of the binding mode for the multimodal antidepressant drug vortioxetine to the human 5-HT3A receptor
LK Ladefoged, L Munro, AJ Pedersen, SCR Lummis, B Bang-Andersen, ...
Molecular Pharmacology 94 (6), 1421-1434, 2018
202018
Substrate and inhibitor binding to the serotonin transporter: Insights from computational, crystallographic, and functional studies
T Zeppelin, LK Ladefoged, S Sinning, B Schiøtt
Neuropharmacology 161, 107548, 2019
172019
A photoswitchable inhibitor of the human serotonin transporter
B Cheng, J Morstein, LK Ladefoged, JB Maesen, B Schiøtt, S Sinning, ...
ACS chemical neuroscience 11 (9), 1231-1237, 2020
152020
Conformational changes in the 5-HT3A receptor extracellular domain measured by Voltage-Clamp fluorometry
L Munro, LK Ladefoged, V Padmanathan, S Andersen, B Schiøtt, ...
Molecular Pharmacology 96 (6), 720-734, 2019
82019
Molecular modeling of neurological membrane proteins− from binding sites to synapses
LK Ladefoged, T Zeppelin, B Schiøtt
Neuroscience Letters 700, 38-49, 2019
42019
Divergent synthesis of new α-glucosidase inhibitors obtained through a vinyl Grignard-mediated carbocyclisation
IMB Knudsen, C Hedberg, LK Ladefoged, D Ide, A Brinkø, EZ Eikeland, ...
Organic & Biomolecular Chemistry 16 (34), 6250-6261, 2018
42018
Inhibitory effects of fluorinated benzenesulfonamides on insulin fibrillation
SHA Janvand, LK Ladefoged, A Zubrienė, A Sakalauskas, G Christiansen, ...
International journal of biological macromolecules 227, 590-600, 2023
32023
Beneficent and Maleficent Effects of Cations on Bufadienolide Binding to Na+,K+-ATPase
LK Ladefoged, B Schiøtt, NU Fedosova
Journal of Chemical Information and Modeling 61 (2), 976-986, 2021
32021
Binding and activation of serotonergic G-protein coupled receptors by the multimodal antidepressant vortioxetine
LK Ladefoged, R Koch, PC Biggin, B Schiøtt
ACS Chemical Neuroscience 13 (8), 1129-1142, 2022
12022
Geometry and water accessibility of the inhibitor binding site of Na+-pump: Pulse-and CW-EPR study
E Aloi, JH Guo, R Guzzi, RW Jiang, LK Ladefoged, D Marsh, M Esmann, ...
Biophysical Journal 120 (13), 2679-2690, 2021
12021
Structural Determinants for Activity of the Antidepressant Vortioxetine at Human and Rodent 5-HT3 receptors
U López-Sánchez, LJ Munro, LK Ladefoged, AJ Pedersen, CC Brun, ...
bioRxiv, 2024.02. 23.581731, 2024
2024
Potentiation of drug toxicity through virus latency reversal promotes preferential elimination of HIV infected cells
TT Truong, M Hayn, CK Frich, LR Olari, LK Ladefoged, MTJ Olesen, ...
Advanced Therapeutics 5 (11), 2200113, 2022
2022
Molecular Insight into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-HT3A Receptors
LK Ladefoged, L Munro, AS Kristensen, B Schiøtt
Biophysical Journal 116 (3), 479a, 2019
2019
Computational modeling of the serotonergic synapse: Investigations of small molecule binding and effect
LK Ladefoged
2019
The system can't perform the operation now. Try again later.
Articles 1–19