Jae-Won Shin
Jae-Won Shin
Assistant Professor, University of Illinois at Chicago College of Medicine
Verified email at uic.edu - Homepage
Cited by
Cited by
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation
J Swift, IL Ivanovska, A Buxboim, T Harada, PCDP Dingal, J Pinter, ...
Science 341 (6149), 1240104, 2013
Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium
O Chaudhuri, ST Koshy, CB da Cunha, JW Shin, CS Verbeke, KH Allison, ...
Nature materials 13 (10), 970-978, 2014
Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival
T Harada, J Swift, J Irianto, JW Shin, KR Spinler, A Athirasala, ...
The Journal of cell biology 204 (5), 669-682, 2014
Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain
M Raab, J Swift, PCDP Dingal, P Shah, JW Shin, DE Discher
The Journal of cell biology 199 (4), 669-683, 2012
Matrix elasticity regulates lamin-A, C phosphorylation and turnover with feedback to actomyosin
A Buxboim, J Swift, J Irianto, KR Spinler, PCDP Dingal, A Athirasala, ...
Current Biology 24 (16), 1909-1917, 2014
Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery
AS Mao*, JW Shin*, S Utech, H Wang, O Uzun, W Li, M Cooper, Y Hu, ...
Nature Materials 16 (2), 236-243, 2017
Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation
AS Mao, JW Shin, DJ Mooney
Biomaterials 98, 184-191, 2016
Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells
JW Shin, KR Spinler, J Swift, JA Chasis, N Mohandas, DE Discher
Proceedings of the National Academy of Sciences 110 (47), 18892-18897, 2013
Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells
JW Shin, A Buxboim, KR Spinler, J Swift, DA Christian, CA Hunter, C Léon, ...
Cell stem cell 14 (1), 81-93, 2014
Stem cell mechanobiology: diverse lessons from bone marrow
IL Ivanovska, JW Shin, J Swift, DE Discher
Trends in cell biology 25 (9), 523-532, 2015
Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes
JW Shin, J Swift, KR Spinler, DE Discher
Proceedings of the National Academy of Sciences 108 (28), 11458-11463, 2011
Extracellular matrix stiffness causes systematic variations in proliferation and chemosensitivity in myeloid leukemias
JW Shin, DJ Mooney
Proceedings of the National Academy of Sciences 113 (43), 12126-12131, 2016
Coordinated increase of nuclear tension and lamin-A with matrix stiffness out-competes Lamin-B Receptor which favors soft tissue phenotypes
A Buxboim, J Irianto, J Swift, A Athirasala, JW Shin, F Rehfeldt, ...
Molecular Biology of the Cell, mbc. E17-06-0393, 2017
Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates
JW Shin, J Swift, I Ivanovska, KR Spinler, A Buxboim, DE Discher
Differentiation 86 (3), 77-86, 2013
RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation
A Suzuki, JW Shin, Y Wang, SH Min, M Poncz, JK Choi, DE Discher, ...
PloS one 8 (7), e69315, 2013
Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia
KR Spinler, JW Shin, MP Lambert, DE Discher
Blood 125 (3), 525-533, 2015
Improving Stem Cell Therapeutics with Mechanobiology
JW Shin, DJ Mooney
Cell stem cell 18 (1), 16-19, 2016
Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation
AS Mao, B Özkale, NJ Shah, KH Vining, T Descombes, L Zhang, ...
Proceedings of the National Academy of Sciences, 201819415, 2019
Matrix elasticity in vitro controls muscle stem cell fate in vivo
M Raab, JW Shin, DE Discher
Stem cell research & therapy 1 (5), 1, 2010
Distribution of glutamate transporter GLAST in membranes of cultured astrocytes in the presence of glutamate transport substrates and ATP
JW Shin, KTD Nguyen, DV Pow, T Knight, V Buljan, MR Bennett, ...
Neurochemical research 34 (10), 1758-1766, 2009
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