| Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation J Swift, IL Ivanovska, A Buxboim, T Harada, PCDP Dingal, J Pinter, ... Science 341 (6149), 1240104, 2013 | 1236 | 2013 |
| Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium O Chaudhuri, ST Koshy, CB da Cunha, JW Shin, CS Verbeke, KH Allison, ... Nature materials 13 (10), 970-978, 2014 | 518 | 2014 |
| Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival T Harada, J Swift, J Irianto, JW Shin, KR Spinler, A Athirasala, ... The Journal of cell biology 204 (5), 669-682, 2014 | 407 | 2014 |
| Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain M Raab, J Swift, PCDP Dingal, P Shah, JW Shin, DE Discher The Journal of cell biology 199 (4), 669-683, 2012 | 243 | 2012 |
| Matrix elasticity regulates lamin-A, C phosphorylation and turnover with feedback to actomyosin A Buxboim, J Swift, J Irianto, KR Spinler, PCDP Dingal, A Athirasala, ... Current Biology 24 (16), 1909-1917, 2014 | 217 | 2014 |
| Deterministic encapsulation of single cells in thin tunable microgels for niche modelling and therapeutic delivery AS Mao*, JW Shin*, S Utech, H Wang, O Uzun, W Li, M Cooper, Y Hu, ... Nature Materials 16 (2), 236-243, 2017 | 159 | 2017 |
| Effects of substrate stiffness and cell-cell contact on mesenchymal stem cell differentiation AS Mao, JW Shin, DJ Mooney Biomaterials 98, 184-191, 2016 | 140 | 2016 |
| Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells JW Shin, KR Spinler, J Swift, JA Chasis, N Mohandas, DE Discher Proceedings of the National Academy of Sciences 110 (47), 18892-18897, 2013 | 137 | 2013 |
| Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells JW Shin, A Buxboim, KR Spinler, J Swift, DA Christian, CA Hunter, C Léon, ... Cell stem cell 14 (1), 81-93, 2014 | 122 | 2014 |
| Stem cell mechanobiology: diverse lessons from bone marrow IL Ivanovska, JW Shin, J Swift, DE Discher Trends in cell biology 25 (9), 523-532, 2015 | 100 | 2015 |
| Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes JW Shin, J Swift, KR Spinler, DE Discher Proceedings of the National Academy of Sciences 108 (28), 11458-11463, 2011 | 85 | 2011 |
| Extracellular matrix stiffness causes systematic variations in proliferation and chemosensitivity in myeloid leukemias JW Shin, DJ Mooney Proceedings of the National Academy of Sciences 113 (43), 12126-12131, 2016 | 75 | 2016 |
| Coordinated increase of nuclear tension and lamin-A with matrix stiffness out-competes Lamin-B Receptor which favors soft tissue phenotypes A Buxboim, J Irianto, J Swift, A Athirasala, JW Shin, F Rehfeldt, ... Molecular Biology of the Cell, mbc. E17-06-0393, 2017 | 63 | 2017 |
| Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates JW Shin, J Swift, I Ivanovska, KR Spinler, A Buxboim, DE Discher Differentiation 86 (3), 77-86, 2013 | 51 | 2013 |
| RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation A Suzuki, JW Shin, Y Wang, SH Min, M Poncz, JK Choi, DE Discher, ... PloS one 8 (7), e69315, 2013 | 41 | 2013 |
| Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia KR Spinler, JW Shin, MP Lambert, DE Discher Blood 125 (3), 525-533, 2015 | 40 | 2015 |
| Improving Stem Cell Therapeutics with Mechanobiology JW Shin, DJ Mooney Cell stem cell 18 (1), 16-19, 2016 | 27 | 2016 |
| Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation AS Mao, B Özkale, NJ Shah, KH Vining, T Descombes, L Zhang, ... Proceedings of the National Academy of Sciences, 201819415, 2019 | 23 | 2019 |
| Matrix elasticity in vitro controls muscle stem cell fate in vivo M Raab, JW Shin, DE Discher Stem cell research & therapy 1 (5), 1, 2010 | 22 | 2010 |
| Distribution of glutamate transporter GLAST in membranes of cultured astrocytes in the presence of glutamate transport substrates and ATP JW Shin, KTD Nguyen, DV Pow, T Knight, V Buljan, MR Bennett, ... Neurochemical research 34 (10), 1758-1766, 2009 | 22 | 2009 |
Dennis DischerUniversity of PennsylvaniaVerified email at seas.upenn.edu
