| Dynamic coupling and allosteric networks in the alpha subunit of heterotrimeric G proteins XQ Yao, R Malik, NW Griggs, L Skjærven, JR Traynor, ... Biophysical Journal 110 (3), 427a, 2016 | 79 | 2016 |
| Further optimization and evaluation of bioavailable, mixed-efficacy μ-opioid receptor (MOR) agonists/δ-opioid receptor (DOR) antagonists: balancing MOR and DOR affinities AA Harland, L Yeomans, NW Griggs, JP Anand, ID Pogozheva, ... Journal of medicinal chemistry 58 (22), 8952-8969, 2015 | 47 | 2015 |
| Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation NT Snider, JM Leonard, R Kwan, NW Griggs, L Rui, MB Omary Journal of Cell Biology 200 (3), 241-247, 2013 | 45 | 2013 |
| In vivo effects of μ‐opioid receptor agonist/δ‐opioid receptor antagonist peptidomimetics following acute and repeated administration JP Anand, KE Kochan, AF Nastase, D Montgomery, NW Griggs, ... British journal of pharmacology 175 (11), 2013-2027, 2018 | 37 | 2018 |
| Effects of N-Substitutions on the Tetrahydroquinoline (THQ) Core of Mixed-Efficacy μ-Opioid Receptor (MOR)/δ-Opioid Receptor (DOR) Ligands AA Harland, AM Bender, NW Griggs, C Gao, JP Anand, ID Pogozheva, ... Journal of Medicinal Chemistry 59 (10), 4985-4998, 2016 | 36 | 2016 |
| Lamin aggregation is an early sensor of porphyria-induced liver injury A Singla, NW Griggs, R Kwan, NT Snider, D Maitra, SA Ernst, H Herrmann, ... Journal of cell science 126 (14), 3105-3112, 2013 | 33 | 2013 |
| Asymmetric synthesis and in vitro and in vivo activity of tetrahydroquinolines featuring a diverse set of polar substitutions at the 6 position as mixed-efficacy μ opioid … AM Bender, NW Griggs, JP Anand, JR Traynor, EM Jutkiewicz, ... ACS chemical neuroscience 6 (8), 1428-1435, 2015 | 31 | 2015 |
| CD73 (ecto‐5′‐nucleotidase) hepatocyte levels differ across mouse strains and contribute to mallory‐denk body formation NT Snider, NW Griggs, A Singla, DS Moons, SVW Weerasinghe, AS Lok, ... Hepatology 58 (5), 1790-1800, 2013 | 30 | 2013 |
| Rapid Synthesis of Boc-2′,6′-dimethyl-l-tyrosine and Derivatives and Incorporation into Opioid Peptidomimetics AM Bender, NW Griggs, C Gao, TJ Trask, JR Traynor, HI Mosberg ACS Medicinal Chemistry Letters 6 (12), 1199-1203, 2015 | 25 | 2015 |
| Synthesis and pharmacological evaluation of novel C-8 substituted tetrahydroquinolines as balanced-affinity mu/delta opioid ligands for the treatment of pain AF Nastase, NW Griggs, JP Anand, TJ Fernandez, AA Harland, TJ Trask, ... ACS chemical neuroscience 9 (7), 1840-1848, 2018 | 22 | 2018 |
| Benzylideneoxymorphone: A new lead for development of bifunctional mu/delta opioid receptor ligands JR Healy, P Bezawada, NW Griggs, AL Devereaux, RR Matsumoto, ... Bioorganic & medicinal chemistry letters 27 (3), 666-669, 2017 | 20 | 2017 |
| Structural simplification of a tetrahydroquinoline-core peptidomimetic μ-opioid receptor (MOR) agonist/δ-opioid receptor (DOR) antagonist produces improved metabolic stability SP Henry, TJ Fernandez, JP Anand, NW Griggs, JR Traynor, HI Mosberg Journal of medicinal chemistry 62 (8), 4142-4157, 2019 | 12 | 2019 |
| Dual pharmacophores explored via structure–activity relationship (SAR) matrix: insights into potent, bifunctional opioid ligand design AF Nastase, JP Anand, AM Bender, D Montgomery, NW Griggs, ... Journal of medicinal chemistry 62 (8), 4193-4203, 2019 | 10 | 2019 |
| Directed ortho Metalation (DoM)-Linked Corriu–Kumada, Negishi, and Suzuki–Miyaura Cross-Coupling Protocols: A Comparative Study CA Quesnelle, V Snieckus Synthesis 50 (22), 4395-4412, 2018 | 10 | 2018 |
| Placement of hydroxy moiety on pendant of peptidomimetic scaffold modulates mu and kappa opioid receptor efficacy AA Harland, ID Pogozheva, NW Griggs, TJ Trask, JR Traynor, HI Mosberg ACS Chemical Neuroscience 8 (11), 2549-2557, 2017 | 10 | 2017 |
| Novel Dimethyltyrosine–Tetrahydroisoquinoline Peptidomimetics with Aromatic Tetrahydroisoquinoline Substitutions Show in Vitro Kappa and Mu Opioid Receptor … D Montgomery, JP Anand, NW Griggs, TJ Fernandez, JG Hartman, ... ACS chemical neuroscience 10 (8), 3682-3689, 2019 | 5 | 2019 |
| Structural evolution of novel opioid peptidomimetics with reduced abuse liabilities S Henry, N Griggs, J Anand, B Sears, J Traynor, E Jutkiewicz, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Bifunctional Opioid Peptidomimetics: Studies on Affinity and Efficacy N Griggs | | 2019 |
| Design and synthesis of novel opioid peptidomimetics for potential treatment of cocaine addiction D Montgomery, J Anand, N Griggs, J Traynor, H Mosberg ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
| A Novel Approach to Safer Analgesics: Mu Opioid Receptor Agonist & Delta Opioid Receptor Antagonist Peptidomimetics TJ Fernández, N Griggs, A Nastase, J Anand, EJ Jutkiewicz, H Mosberg, ... The FASEB Journal 32, 689.6-689.6, 2018 | | 2018 |
