Stuart McDonald
Stuart McDonald
Senior Lecturer in Gastroenterology , Barts Cancer Institute, Barts and the London School of
Verified email at qmul.ac.uk - Homepage
Title
Cited by
Cited by
Year
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission
LC Greaves, SL Preston, PJ Tadrous, RW Taylor, MJ Barron, D Oukrif, ...
Proceedings of the National Academy of Sciences 103 (3), 714-719, 2006
2812006
Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells
SAC McDonald, LC Greaves, L Gutierrez–Gonzalez, M Rodriguez–Justo, ...
Gastroenterology 134 (2), 500-510, 2008
2322008
Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion …
LM Higgins, SAC McDonald, N Whittle, N Crockett, JG Shields, ...
The Journal of Immunology 162 (1), 486-493, 1999
2221999
Detection of intestinal metaplasia in Barrett's esophagus: an observational comparator study suggests the need for a minimum of eight biopsies
R Harrison, I Perry, W Haddadin, S McDonald, R Bryan, K Abrams, ...
American Journal of Gastroenterology 102 (6), 1154-1161, 2007
2192007
Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett’s oesophagus
SJ Leedham, SL Preston, SAC McDonald, G Elia, P Bhandari, D Poller, ...
Gut 57 (8), 1041-1048, 2008
2062008
Intestinal stem cells
SJ Leedham, M Brittan, SAC McDonald, NA Wright
Journal of cellular and molecular medicine 9 (1), 11-24, 2005
1872005
Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway
PJ Pollard, B Spencer-Dene, D Shukla, K Howarth, E Nye, M El-Bahrawy, ...
Cancer cell 11 (4), 311-319, 2007
1702007
Quantification of crypt and stem cell evolution in the normal and neoplastic human colon
AM Baker, B Cereser, S Melton, AG Fletcher, M Rodriguez-Justo, ...
Cell reports 8 (4), 940-947, 2014
1672014
Locating the stem cell niche and tracing hepatocyte lineages in human liver
TG Fellous, S Islam, PJ Tadrous, G Elia, HM Kocher, S Bhattacharya, ...
Hepatology 49 (5), 1655-1663, 2009
1652009
Clonality, founder mutations, and field cancerization in human ulcerative colitis–associated neoplasia
SJ Leedham, TA Graham, D Oukrif, SAC McDonald, M Rodriguez–Justo, ...
Gastroenterology 136 (2), 542-550. e6, 2009
1622009
Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread
PP Wong, F Demircioglu, E Ghazaly, W Alrawashdeh, MRL Stratford, ...
Cancer cell 27 (1), 123-137, 2015
1482015
Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas
C Thirlwell, OCC Will, E Domingo, TA Graham, SAC McDonald, D Oukrif, ...
Gastroenterology 138 (4), 1441-1454. e7, 2010
1432010
Mechanisms of disease: from stem cells to colorectal cancer
SAC McDonald, SL Preston, MJ Lovell, NA Wright, JAZ Jankowski
Nature Clinical Practice Gastroenterology & Hepatology 3 (5), 267-274, 2006
1162006
Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors
VH Teixeira, P Nadarajan, TA Graham, CP Pipinikas, JM Brown, M Falzon, ...
Elife 2, e00966, 2013
942013
The clonal origins of dysplasia from intestinal metaplasia in the human stomach
L Gutierrez–Gonzalez, TA Graham, M Rodriguez–Justo, SJ Leedham, ...
Gastroenterology 140 (4), 1251-1260. e6, 2011
932011
The histogenesis of regenerative nodules in human liver cirrhosis
WR Lin, SN Lim, SAC McDonald, T Graham, VL Wright, CL Peplow, ...
Hepatology 51 (3), 1017-1026, 2010
882010
Characterization of the mucosal cell‐mediated immune response in IL‐2 knockout mice before and after the onset of colitis
SAC McDonald, M Palmen, EP Van Rees, TT MacDonald
Immunology 91 (1), 73-80, 1997
851997
Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution
A Humphries, B Cereser, LJ Gay, DSJ Miller, B Das, A Gutteridge, G Elia, ...
Proceedings of the National Academy of Sciences 110 (27), E2490-E2499, 2013
802013
Field cancerization in the intestinal epithelium of patients with Crohn's ileocolitis
S Galandiuk, M Rodriguez–Justo, R Jeffery, AM Nicholson, Y Cheng, ...
Gastroenterology 142 (4), 855-864. e8, 2012
802012
Ectopic expression of P-cadherin correlates with promoter hypomethylation early in colorectal carcinogenesis and enhanced intestinal crypt fission in vivo
A Milicic, LA Harrison, RA Goodlad, RG Hardy, AM Nicholson, M Presz, ...
Cancer research 68 (19), 7760-7768, 2008
742008
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