Follow
Tim Majarian
Tim Majarian
Research Scientist, Vertex Pharmaceuticals
Verified email at vrtx.com
Title
Cited by
Cited by
Year
High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease
H Kim, KE Westerman, K Smith, J Chiou, JB Cole, T Majarian, ...
Diabetologia 66 (3), 495-507, 2023
262023
Variance-quantitative trait loci enable systematic discovery of gene-environment interactions for cardiometabolic serum biomarkers
KE Westerman, TD Majarian, F Giulianini, DK Jang, J Miao, JC Florez, ...
Nature Communications 13 (1), 3993, 2022
242022
Point process models for localization and interdependence of punctate cellular structures
Y Li, TD Majarian, AW Naik, GR Johnson, RF Murphy
Cytometry Part A 89 (7), 633-643, 2016
152016
Rare non-coding variation identified by large scale whole genome sequencing reveals unexplained heritability of type 2 diabetes
J Wessel, TD Majarian, HM Highland, S Raghavan, MD Szeto, ...
MedRxiv, 2020.11. 13.20221812, 2020
132020
Learning the sequence of influenza A genome assembly during viral replication using point process models and fluorescence in situ hybridization
TD Majarian, RF Murphy, SS Lakdawala
Plos Computational Biology 15 (1), e1006199, 2019
132019
Gene-lifestyle interactions in the genomics of human complex traits
V Laville, T Majarian, YJ Sung, K Schwander, MF Feitosa, DI Chasman, ...
European Journal of Human Genetics 30 (6), 730-739, 2022
122022
Association and interaction of genetics and area-level socioeconomic factors on the prevalence of type 2 diabetes and obesity
SJ Cromer, CM Lakhani, JM Mercader, TD Majarian, P Schroeder, ...
Diabetes Care 46 (5), 944-952, 2023
102023
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program
D DiCorpo, SM Gaynor, EM Russell, KE Westerman, LM Raffield, ...
Communications biology 5 (1), 756, 2022
82022
Cellorganizer: Learning and using cell geometries for spatial cell simulations
TD Majarian, I Cao-Berg, X Ruan, RF Murphy
Modeling Biomolecular Site Dynamics: Methods and Protocols, 251-264, 2019
62019
Deriving stratified effects from joint models investigating gene-environment interactions
V Laville, T Majarian, PS De Vries, AR Bentley, MF Feitosa, YJ Sung, ...
BMC bioinformatics 21, 1-11, 2020
42020
Specificity of CRISPR-Cas9 editing in exagamglogene autotemcel
A Yen, Z Zappala, RS Fine, TD Majarian, P Sripakdeevong, D Altshuler
New England Journal of Medicine, 2024
32024
Polygenic scores help reduce racial disparities in predictive accuracy of automated type 1 diabetes classification algorithms
AJ Deutsch, L Stalbow, TD Majarian, JM Mercader, AK Manning, ...
Diabetes care 46 (4), 794-800, 2023
32023
Large-scale multivariate multi-ancestry Interaction analyses point towards different genetic mechanisms by population and exposure
V Laville, T Majarian, YJ Sung, K Schwander, MF Feitosa, D Chasman, ...
bioRxiv, 562157, 2019
3*2019
A method for characterizing phenotypic changes in highly variable cell populations and its application to high content screening of Arabidopsis thaliana protoplasts
GR Johnson, JD Kangas, A Dovzhenko, R Trojok, K Voigt, TD Majarian, ...
Cytometry Part A 91 (4), 326-335, 2017
32017
Multi-ancestry polygenic mechanisms of type 2 diabetes
K Smith, AJ Deutsch, C McGrail, H Kim, S Hsu, A Huerta-Chagoya, ...
Nature Medicine, 1-10, 2024
22024
Multi-ancestry polygenic mechanisms of type 2 diabetes elucidate disease processes and clinical heterogeneity
K Smith, AJ Deutsch, C McGrail, H Kim, S Hsu, R Mandla, PH Schroeder, ...
medRxiv, 2023
22023
Multi-omics insights into the biological mechanisms underlying statistical gene-by-lifestyle interactions with smoking and alcohol consumption
TD Majarian, AR Bentley, V Laville, MR Brown, DI Chasman, PS de Vries, ...
Frontiers in Genetics 13, 954713, 2022
12022
Multi-omics insights into the biological mechanisms underlying gene-by-lifestyle interactions with smoking and alcohol consumption detected by genome-wide trans-ancestry meta …
TD Majarian, AR Bentley, V Laville, MR Brown, DI Chasman, LA Cupples, ...
medRxiv, 2021.07. 26.21261153, 2021
2021
Encouraging open science, replicability of analysis and collaborative cloud computing for whole genome sequence analysis of complex traits
T Majarian, AK Manning
GENETIC EPIDEMIOLOGY 42 (7), 715-715, 2018
2018
High-throughput Genetic Clustering of Type 2 Diabetes Loci Reveals Heterogeneous Mechanistic Pathways of Metabolic Disease
T Majarian, M von Grotthuss, JM Mercader, SH Kwak, J Kim, JC Florez, ...
The system can't perform the operation now. Try again later.
Articles 1–20