Brian O'Rourke
TitleCited byYear
Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection?
Y Liu, T Sato, B O’Rourke, E Marban
Circulation 97 (24), 2463-2469, 1998
Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
LA Barouch, RW Harrison, MW Skaf, GO Rosas, TP Cappola, ZA Kobeissi, ...
Nature 416 (6878), 337, 2002
Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure
S Kääb, HB Nuss, N Chiamvimonvat, B O’Rourke, PH Pak, DA Kass, ...
Circulation research 78 (2), 262-273, 1996
Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, II: model studies
RL Winslow, J Rice, S Jafri, E Marban, B O’Rourke
Circulation research 84 (5), 571-586, 1999
Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies
B O’Rourke, DA Kass, GF Tomaselli, S Kääb, R Tunin, E Marbán
Circulation research 84 (5), 562-570, 1999
Evidence for Mitochondrial K+ Channels and Their Role in Cardioprotection
B O’Rourke
Circulation research 94 (4), 420-432, 2004
Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop
GI Fishman, SS Chugh, JP DiMarco, CM Albert, ME Anderson, RO Bonow, ...
Circulation 122 (22), 2335-2348, 2010
Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes
MA Aon, S Cortassa, E Marbán, B O'Rourke
Journal of Biological Chemistry 278 (45), 44735-44744, 2003
Cytoprotective role of Ca2+-activated K+ channels in the cardiac inner mitochondrial membrane
W Xu, Y Liu, S Wang, T McDonald, JE Van Eyk, A Sidor, B O'Rourke
Science 298 (5595), 1029-1033, 2002
Myocardial KATP Channels in Preconditioning
B O’Rourke
Circulation research 87 (10), 845-855, 2000
Mitochondrial ATP-Sensitive Potassium Channels Attenuate Matrix Ca2+ Overload During Simulated Ischemia and Reperfusion: Possible Mechanism of …
M Murata, M Akao, B O’Rourke, E Marbán
Circulation research 89 (10), 891-898, 2001
Modulation of Mitochondrial ATP-Dependent K+ Channels by Protein Kinase C
T Sato, B O’Rourke, E Marbán
Circulation Research 83 (1), 110-114, 1998
Nitric oxide regulates exocytosis by S-nitrosylation of N-ethylmaleimide-sensitive factor
K Matsushita, CN Morrell, B Cambien, SX Yang, M Yamakuchi, C Bao, ...
Cell 115 (2), 139-150, 2003
Activation of mitochondrial ATP-dependent potassium channels by nitric oxide
N Sasaki, T Sato, A Ohler, B O’Rourke, E Marbán
Circulation 101 (4), 439-445, 2000
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics
S Cortassa, MA Aon, E Marbán, RL Winslow, B O’Rourke
Biophysical journal 84 (4), 2734-2755, 2003
Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells
M Akao, A Ohler, B O’Rourke, E Marbán
Circulation Research 88 (12), 1267-1275, 2001
Selective Pharmacological Agents Implicate Mitochondrial but Not Sarcolemmal KATP Channels in Ischemic Cardioprotection
T Sato, N Sasaki, J Seharaseyon, B O’Rourke, E Marbán
Circulation 101 (20), 2418-2423, 2000
Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation
MR Abraham, CA Henrikson, L Tung, MG Chang, M Aon, T Xue, RA Li, ...
Circulation research 97 (2), 159-167, 2005
The mitochondrial origin of postischemic arrhythmias
FG Akar, MA Aon, GF Tomaselli, B O’Rourke
The Journal of clinical investigation 115 (12), 3527-3535, 2005
Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure
IA Hobai, B O’Rourke
Circulation 103 (11), 1577-1584, 2001
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Articles 1–20