Sodium recognition by the Na+/Ca2+ exchanger in the outward-facing conformation F Marinelli, L Almagor, R Hiller, M Giladi, D Khananshvili, ... Proceedings of the National Academy of Sciences 111 (50), E5354-E5362, 2014 | 82 | 2014 |
Structural features of ion transport and allosteric regulation in sodium-calcium exchanger (NCX) proteins M Giladi, I Tal, D Khananshvili Frontiers in physiology 7, 30, 2016 | 74 | 2016 |
Proton-sensing Ca2+ binding domains regulate the cardiac Na+/Ca2+ exchanger L Boyman, BM Hagen, M Giladi, R Hiller, WJ Lederer, D Khananshvili Journal of Biological Chemistry 286 (33), 28811-28820, 2011 | 73 | 2011 |
Essential role of the CBD1-CBD2 linker in slow dissociation of Ca2+ from the regulatory two-domain tandem of NCX1 M Giladi, L Boyman, H Mikhasenko, R Hiller, D Khananshvili Journal of Biological Chemistry 285 (36), 28117-28125, 2010 | 57 | 2010 |
Structure-functional basis of ion transport in sodium–calcium exchanger (NCX) proteins M Giladi, R Shor, M Lisnyansky, D Khananshvili International journal of molecular sciences 17 (11), 1949, 2016 | 52 | 2016 |
Asymmetric preorganization of inverted pair residues in the sodium-calcium exchanger M Giladi, L Almagor, L van Dijk, R Hiller, P Man, E Forest, D Khananshvili Scientific reports 6 (1), 20753, 2016 | 44 | 2016 |
A Common Ca2+-Driven Interdomain Module Governs Eukaryotic NCX Regulation M Giladi, Y Sasson, X Fang, R Hiller, T Buki, YX Wang, JA Hirsch, ... PloS one 7 (6), e39985, 2012 | 44 | 2012 |
Dynamic features of allosteric Ca2+ sensor in tissue-specific NCX variants M Giladi, H Bohbot, T Buki, DH Schulze, R Hiller, D Khananshvili Cell calcium 51 (6), 478-485, 2012 | 37 | 2012 |
KCNQ1 channels do not undergo concerted but sequential gating transitions in both the absence and the presence of KCNE1 protein E Meisel, M Dvir, Y Haitin, M Giladi, A Peretz, B Attali Journal of Biological Chemistry 287 (41), 34212-34224, 2012 | 36 | 2012 |
Dynamic distinctions in the Na+/Ca2+ exchanger adopting the inward-and outward-facing conformational states M Giladi, L van Dijk, B Refaeli, L Almagor, R Hiller, P Man, E Forest, ... Journal of Biological Chemistry 292 (29), 12311-12323, 2017 | 35 | 2017 |
Structure-dynamic determinants governing a mode of regulatory response and propagation of allosteric signal in splice variants of Na+/Ca2+ exchange (NCX … M Giladi, SY Lee, R Hiller, KY Chung, D Khananshvili Biochemical Journal 465 (3), 489-501, 2015 | 33 | 2015 |
Population shift underlies Ca2+-induced regulatory transitions in the sodium-calcium exchanger (NCX) M Giladi, R Hiller, JA Hirsch, D Khananshvili Journal of Biological Chemistry 288 (32), 23141-23149, 2013 | 33 | 2013 |
Hydrogen-deuterium exchange mass-spectrometry of secondary active transporters: from structural dynamics to molecular mechanisms M Giladi, D Khananshvili Frontiers in Pharmacology 11, 70, 2020 | 32 | 2020 |
Functional asymmetry of bidirectional Ca2+-movements in an archaeal sodium–calcium exchanger (NCX_Mj) L Almagor, M Giladi, L van Dijk, T Buki, R Hiller, D Khananshvili Cell calcium 56 (4), 276-284, 2014 | 32 | 2014 |
Structure-based dynamic arrays in regulatory domains of sodium-calcium exchanger (NCX) isoforms M Giladi, SY Lee, Y Ariely, Y Teldan, R Granit, R Strulovich, Y Haitin, ... Scientific Reports 7 (1), 993, 2017 | 31 | 2017 |
Convulsive seizures and some behavioral comorbidities are uncoupled in the Scn1aA1783V Dravet syndrome mouse model S Fadila, S Quinn, A Turchetti Maia, D Yakubovich, M Ovadia, ... Epilepsia 61 (10), 2289-2300, 2020 | 30 | 2020 |
Structural basis of heterotetrameric assembly and disease mutations in the human cis-prenyltransferase complex ML Bar-El, P Vaňková, A Yeheskel, L Simhaev, H Engel, P Man, Y Haitin, ... Nature Communications 11 (1), 5273, 2020 | 26 | 2020 |
Structure-based engineering of lithium-transport capacity in an archaeal sodium–calcium exchanger B Refaeli, M Giladi, R Hiller, D Khananshvili Biochemistry 55 (12), 1673-1676, 2016 | 26 | 2016 |
Structure‐dynamic basis of splicing‐dependent regulation in tissue‐specific variants of the sodium‐calcium exchanger SY Lee, M Giladi, H Bohbot, R Hiller, KY Chung, D Khananshvili The FASEB Journal 30 (3), 1356-1366, 2016 | 26 | 2016 |
The C2B domain is the primary Ca2+ sensor in DOC2B: a structural and functional analysis M Giladi, L Michaeli, L Almagor, D Bar-On, T Buki, U Ashery, ... Journal of molecular biology 425 (22), 4629-4641, 2013 | 26 | 2013 |