| Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps NS Nemeria, S Chakraborty, A Balakrishnan, F Jordan The FEBS journal 276 (9), 2432-3446, 2009 | 2297 | 2009 |
| E1 of α-ketoglutarate dehydrogenase defends Mycobacterium tuberculosis against glutamate anaplerosis and nitroxidative stress C Maksymiuk, A Balakrishnan, R Bryk, KY Rhee, CF Nathan Proceedings of the National Academy of Sciences 112 (43), E5834-E5843, 2015 | 64 | 2015 |
| Determination of pre-steady-state rate constants on the Escherichia coli pyruvate dehydrogenase complex reveals that loop movement controls the rate-limiting step A Balakrishnan, NS Nemeria, S Chakraborty, L Kakalis, F Jordan Journal of the American Chemical Society 134 (45), 18644-18655, 2012 | 46 | 2012 |
| Solid-state nuclear magnetic resonance studies delineate the role of the protein in activation of both aromatic rings of thiamin A Balakrishnan, S Paramasivam, S Chakraborty, T Polenova, F Jordan Journal of the American Chemical Society 134 (1), 665-672, 2012 | 35 | 2012 |
| Bifunctionality of the thiamin diphosphate cofactor: assignment of tautomeric/ionization states of the 4′-aminopyrimidine ring when various intermediates occupy the active … A Balakrishnan, Y Gao, P Moorjani, NS Nemeria, K Tittmann, F Jordan Journal of the American Chemical Society 134 (8), 3873-3885, 2012 | 34 | 2012 |
| Solid-state NMR and density functional theory studies of ionization states of thiamin S Paramasivam, A Balakrishnan, O Dmitrenko, A Godert, TP Begley, ... The Journal of Physical Chemistry B 115 (4), 730-736, 2011 | 33 | 2011 |
| Assignment of Function to Histidines 260 and 298 by Engineering the E1 Component of the Escherichia coli 2-Oxoglutarate Dehydrogenase Complex … DJ Shim, NS Nemeria, A Balakrishnan, H Patel, J Song, J Wang, F Jordan, ... Biochemistry 50 (35), 7705-7709, 2011 | 26 | 2011 |
| Influence of allosteric regulators on individual steps in the reaction catalyzed by Mycobacterium tuberculosis 2-hydroxy-3-oxoadipate synthase A Balakrishnan, F Jordan, CF Nathan Journal of Biological Chemistry 288 (30), 21688-21702, 2013 | 22 | 2013 |
| Detection and time course of formation of major thiamin diphosphate-bound covalent intermediates derived from a chromophoric substrate analogue on benzoylformate decarboxylase S Chakraborty, NS Nemeria, A Balakrishnan, GS Brandt, MM Kneen, ... Biochemistry 48 (5), 981-994, 2009 | 22 | 2009 |
| Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase R Bryk, N Arango, C Maksymiuk, A Balakrishnan, YT Wu, CH Wong, ... Biochemistry 52 (51), 9375-9384, 2013 | 21 | 2013 |
| Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4′-aminopyrimidinium and 1′, 4′-iminopyrimidine tautomeric forms in the … N Nemeria, E Binshtein, H Patel, A Balakrishnan, I Vered, B Shaanan, ... Biochemistry 51 (40), 7940-7952, 2012 | 21 | 2012 |
| Comparison of transposon and deletion mutants in Mycobacterium tuberculosis: The case of rv1248c, encoding 2-hydroxy-3-oxoadipate synthase C Maksymiuk, T Ioerger, A Balakrishnan, R Bryk, K Rhee, J Sacchettini, ... Tuberculosis 95 (6), 689-694, 2015 | 13 | 2015 |
| Molecular basis for antiviral action of EDP-235: A potent and selective SARS-CoV-2 3CLpro inhibitor for the treatment of COVID-19. A Balakrishnan, A Reyes, R Shen, N Bisht, J Sweeney, R Levene, ... ACE 2, 50, 2022 | 6 | 2022 |
| Biochemical characterization of respiratory syncytial virus RNA-dependent RNA polymerase complex A Balakrishnan, E Price, C Luu, J Shaul, C Wartchow, J Cantwell, T Vo, ... ACS infectious diseases 6 (10), 2800-2811, 2020 | 5 | 2020 |
| Thiamin diphosphate catalysis in Escherichia coli pyruvate dehydrogenase multi-enzyme complex: Activation, covalent electrophilic catalysis, and substrate … A Balakrishnan Rutgers The State University of New Jersey, Graduate School-Newark, 2011 | | 2011 |
| Defining states of ionization and tautomerization of thiamin diphosphate at individual reaction intermediates on enzymes: Enzymes that use a rare tautomeric form F Jordan, NS Nemeria, A Balakrishnan, S Paramasivam, T Polenova ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010 | | 2010 |
| Altering the substrate specificity of the Escherichia coli E1 Component of the 2‐Oxoglutarate Dehydrogenase Multienzyme Complex DJ Shim, NS Nemeria, A Balakrishnan, F Jordan, ET Farinas The FASEB Journal 24, 645.6-645.6, 2010 | | 2010 |
| Pre‐steady State Kinetic Analysis of Covalent Intermediates on the E. coli Pyruvate Dehydrogenase Complex A Balakrishnan, F Jordan The FASEB Journal 24, 465.1-465.1, 2010 | | 2010 |
Frank JordanRutgers Board of Governors Professor of Chemistry, Rutgers UniversityVerified email at newark.rutgers.edu
