| Physical stability of proteins in aqueous solution: mechanism and driving forces in nonnative protein aggregation EY Chi, S Krishnan, TW Randolph, JF Carpenter Pharmaceutical research 20 (9), 1325-1336, 2003 | 1427 | 2003 |
| Rational design of stable lyophilized protein formulations: some practical advice JF Carpenter, MJ Pikal, BS Chang, TW Randolph Pharmaceutical research 14 (8), 969-975, 1997 | 831 | 1997 |
| Water in Carbon-Dioxide Microemulsions-An Environment for Hydrophiles Including Proteins KP Johnston, KL Harrison, MJ Clarke, SM Howdle, MP Heitz, FV Bright, ... Science 271 (5249), 624-626, 1996 | 753 | 1996 |
| Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding SD Allison, B Chang, TW Randolph, JF Carpenter Archives of Biochemistry and Biophysics 365 (2), 289-298, 1999 | 568 | 1999 |
| Overlooking subvisible particles in therapeutic protein products: Gaps that may compromise product quality JF Carpenter, TW Randolph, WIM Jiskoot, DJA Crommelin, CR Middaugh, ... Journal of pharmaceutical sciences 98 (4), 1201-1205, 2008 | 493 | 2008 |
| Cavitation and the interaction between macroscopic hydrophobic surfaces HK Christenson, PM Claesson Science 239 (4838), 390-392, 1988 | 460 | 1988 |
| The ice nucleation temperature determines the primary drying rate of lyophilization for samples frozen on a temperature‐controlled shelf JA Searles, JF Carpenter, TW Randolph Journal of pharmaceutical sciences 90 (7), 860-871, 2001 | 370 | 2001 |
| Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor EY Chi, S Krishnan, BS Kendrick, BS Chang, JF Carpenter, TW Randolph Protein science 12 (5), 903-913, 2009 | 355 | 2009 |
| Rational design of stable lyophilized protein formulations: theory and practice JF Carpenter, BS Chang, W Garzon-Rodriguez, TW Randolph Rational Design of Stable Protein Formulations, 109-133, 2002 | 327 | 2002 |
| Sub-micrometer-sized biodegradable particles of poly (L-lactic acid) via the gas antisolvent spray precipitation process TW Randolph, AD Randolph, M Mebes, S Yeung Biotechnology progress 9 (4), 429-435, 1993 | 322 | 1993 |
| Enzymatic catalysis in a supercritical fluid TW Randolph, HW Blanch, JM Prausnitz, CR Wilke Biotechnology letters 7 (5), 325-328, 1985 | 321 | 1985 |
| Tween protects recombinant human growth hormone against agitation‐induced damage via hydrophobic interactions NB Bam, JL Cleland, J Yang, MC Manning, JF Carpenter, RF Kelley, ... Journal of pharmaceutical sciences 87 (12), 1554-1559, 1998 | 315 | 1998 |
| Annealing to optimize the primary drying rate, reduce freezing‐induced drying rate heterogeneity, and determine Tg′ in pharmaceutical lyophilization JA Searles, JF Carpenter, TW Randolph Journal of pharmaceutical sciences 90 (7), 872-887, 2001 | 294 | 2001 |
| Effects of Tween 20® and Tween 80® on the stability of Albutropin during agitation DK Chou, R Krishnamurthy, TW Randolph, JF Carpenter, MC Manning Journal of pharmaceutical sciences 94 (6), 1368-1381, 2005 | 282 | 2005 |
| Solubilization of Pharmaceutical Substances in an Organic Solvent and Preparation of Pharmaceutical Powders Using the Same MC Manning, TW Randolph, E Shefter, RF Falk US Patent 5,981,474, 1999 | 275 | 1999 |
| Effect of Tween 20 on freeze‐thawing‐and agitation‐induced aggregation of recombinant human factor XIII L Krielgaard, LS Jones, TW Randolph, S Frokjaer, JM Flink, MC Manning, ... Journal of pharmaceutical sciences 87 (12), 1593-1603, 1998 | 250 | 1998 |
| Silicone oil-and agitation-induced aggregation of a monoclonal antibody in aqueous solution R Thirumangalathu, S Krishnan, MS Ricci, DN Brems, TW Randolph, ... Journal of pharmaceutical sciences 98 (9), 3167-3181, 2009 | 244 | 2009 |
| Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: Role in restricted conformational mobility and compaction of native state BS Kendrick, BS Chang, T Arakawa, B Peterson, TW Randolph, ... Proceedings of the National Academy of Sciences 94 (22), 11917-11922, 1997 | 240 | 1997 |
| A transient expansion of the native state precedes aggregation of recombinant human interferon-γ BS Kendrick, JF Carpenter, JL Cleland, TW Randolph Proceedings of the National Academy of Sciences 95 (24), 14142-14146, 1998 | 225 | 1998 |
| High pressure fosters protein refolding from aggregates at high concentrations RJS John, JF Carpenter, TW Randolph Proceedings of the National Academy of Sciences 96 (23), 13029-13033, 1999 | 224 | 1999 |
Eva Y. ChiProfessor and Regents' Lecturer, Dept of Chem & Biol Eng, University of New MexicoVerified email at unm.edu
