Tug-of-war in motor protein ensembles revealed with a programmable DNA origami scaffold ND Derr, BS Goodman, R Jungmann, AE Leschziner, WM Shih, ... Science 338 (6107), 662-665, 2012 | 487 | 2012 |
Lis1 acts as a “clutch” between the ATPase and microtubule-binding domains of the dynein motor J Huang, AJ Roberts, AE Leschziner, SL Reck-Peterson Cell 150 (5), 975-986, 2012 | 269 | 2012 |
Mechanism and regulation of cytoplasmic dynein MA Cianfrocco, ME DeSantis, AE Leschziner, SL Reck-Peterson Annual review of cell and developmental biology 31, 83-108, 2015 | 251 | 2015 |
Molecular architecture of the ATP-dependent chromatin-remodeling complex SWR1 VQ Nguyen, A Ranjan, F Stengel, D Wei, R Aebersold, C Wu, ... Cell 154 (6), 1220-1231, 2013 | 187 | 2013 |
Structural basis for microtubule binding and release by dynein WB Redwine, R Hernández-López, S Zou, J Huang, SL Reck-Peterson, ... Science 337 (6101), 1532-1536, 2012 | 186 | 2012 |
Structural basis for the initiation of eukaryotic transcription-coupled DNA repair J Xu, I Lahiri, W Wang, A Wier, MA Cianfrocco, J Chong, AA Hare, ... Nature 551 (7682), 653-657, 2017 | 174 | 2017 |
Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction CK Deniston, J Salogiannis, S Mathea, DM Snead, I Lahiri, ... Nature 588 (7837), 344-349, 2020 | 169 | 2020 |
The orthogonal tilt reconstruction method: an approach to generating single-class volumes with no missing cone for ab initio reconstruction of asymmetric particles AE Leschziner, E Nogales Journal of structural biology 153 (3), 284-299, 2006 | 124 | 2006 |
Lis1 regulates dynein by sterically blocking its mechanochemical cycle K Toropova, S Zou, AJ Roberts, WB Redwine, BS Goodman, ... Elife 3, e03372, 2014 | 121 | 2014 |
Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms HW Wang, VH Ramey, S Westermann, AE Leschziner, JPI Welburn, ... Nature structural & molecular biology 14 (8), 721-726, 2007 | 120 | 2007 |
Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method AE Leschziner, A Saha, J Wittmeyer, Y Zhang, C Bustamante, BR Cairns, ... Proceedings of the National Academy of Sciences 104 (12), 4913-4918, 2007 | 117 | 2007 |
Nucleotide-dependent conformational changes in the DnaA-like core of the origin recognition complex MG Clarey, JP Erzberger, P Grob, AE Leschziner, JM Berger, E Nogales, ... Nature structural & molecular biology 13 (8), 684-690, 2006 | 110 | 2006 |
Visualizing flexibility at molecular resolution: analysis of heterogeneity in single-particle electron microscopy reconstructions AE Leschziner, E Nogales Annu. Rev. Biophys. Biomol. Struct. 36, 43-62, 2007 | 108 | 2007 |
DNA transposition: from a black box to a color monitor NDF Grindley, AE Leschziner Cell 83 (7), 1063-1066, 1995 | 95 | 1995 |
Lis1 has two opposing modes of regulating cytoplasmic dynein ME DeSantis, MA Cianfrocco, ZM Htet, PT Tran, SL Reck-Peterson, ... Cell 170 (6), 1197-1208. e12, 2017 | 90 | 2017 |
LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes ZM Htet, JP Gillies, RW Baker, AE Leschziner, ME DeSantis, ... Nature cell biology 22 (5), 518-525, 2020 | 86 | 2020 |
A model for the γδ resolvase synaptic complex GJ Sarkis, LL Murley, AE Leschziner, MR Boocock, WM Stark, ... Molecular cell 8 (3), 623-631, 2001 | 86 | 2001 |
COSMIC2: A science gateway for cryo-electron microscopy structure determination MA Cianfrocco, M Wong-Barnum, C Youn, R Wagner, A Leschziner Proceedings of the Practice and Experience in Advanced Research Computing …, 2017 | 85 | 2017 |
A dimeric structure for archaeal box C/D small ribonucleoproteins F Bleichert, KT Gagnon, BA Brown, ES Maxwell, AE Leschziner, ... Science 325 (5946), 1384-1387, 2009 | 71 | 2009 |
Neural Regulation of α‐Dystroglycan Biosynthesis and Glycosylation in Skeletal Muscle A Leschziner, H Moukhles, M Lindenbaum, SH Gee, J Butterworth, ... Journal of neurochemistry 74 (1), 70-80, 2000 | 67 | 2000 |