Conformation of the human immunoglobulin G2 hinge imparts superagonistic properties to immunostimulatory anticancer antibodies AL White, HTC Chan, RR French, J Willoughby, CI Mockridge, ... Cancer cell 27 (1), 138-148, 2015 | 214 | 2015 |
Langerhans cells—programmed by the epidermis K Clayton, AF Vallejo, J Davies, S Sirvent, ME Polak Frontiers in immunology 8, 316131, 2017 | 160 | 2017 |
Mechanisms of local immunosuppression in cutaneous melanoma ME Polak, NJ Borthwick, FG Gabriel, P Johnson, B Higgins, J Hurren, ... British journal of cancer 96 (12), 1879-1887, 2007 | 153 | 2007 |
Sensitization via healthy skin programs Th2 responses in individuals with atopic dermatitis L Newell, ME Polak, J Perera, C Owen, P Boyd, C Pickard, PH Howarth, ... Journal of Investigative Dermatology 133 (10), 2372-2380, 2013 | 118 | 2013 |
In vitro diagnostic assays are effective during the acute phase of delayed‐type drug hypersensitivity reactions ME Polak, G Belgi, C McGuire, C Pickard, E Healy, PS Friedmann, ... British Journal of Dermatology 168 (3), 539-549, 2013 | 84 | 2013 |
OX40+ Regulatory T Cells in Cutaneous Squamous Cell Carcinoma Suppress Effector T-Cell Responses and Associate with Metastatic Potential C Lai, S August, A Albibas, R Behar, SY Cho, ME Polak, J Theaker, ... Clinical Cancer Research 22 (16), 4236-4248, 2016 | 80 | 2016 |
CD70–CD27 Interaction Augments CD8+ T-Cell Activation by Human Epidermal Langerhans Cells ME Polak, L Newell, VY Taraban, C Pickard, E Healy, PS Friedmann, ... Journal of Investigative Dermatology, 2012 | 79 | 2012 |
Distinct molecular signature of human skin Langerhans cells denotes critical differences in cutaneous dendritic cell immune regulation ME Polak, SM Thirdborough, CY Ung, T Elliott, E Healy, TC Freeman, ... Journal of Investigative Dermatology 134 (3), 695-703, 2014 | 58 | 2014 |
Melanoma vaccines: the problems of local immunosuppression ME Polak, NJ Borthwick, MJ Jager, IA Cree Human immunology 70 (5), 331-339, 2009 | 48 | 2009 |
Resistance gene expression determines the in vitro chemosensitivity of non-small cell lung cancer (NSCLC) S Glaysher, D Yiannakis, F Gabriel, P Johnson, M Polak, L Knight, ... BMC cancer 9 (1), 300, 2009 | 44 | 2009 |
Doxycycline host-directed therapy in human pulmonary tuberculosis QH Miow, AF Vallejo, Y Wang, JM Hong, C Bai, FSW Teo, ADY Wang, ... The Journal of clinical investigation 131 (15), 2021 | 37 | 2021 |
Petri Net computational modelling of Langerhans cell Interferon Regulatory Factor Network predicts their role in T cell activation ME Polak, CY Ung, J Masapust, TC Freeman, MR Ardern-Jones Scientific reports 7 (1), 668, 2017 | 35 | 2017 |
Characteristics of immunosuppressive regulatory T cells in cutaneous squamous cell carcinomas and role in metastasis C Lai, S August, R Behar, M Polak, M Ardern-Jones, J Theaker, ... The Lancet 385, S59, 2015 | 35 | 2015 |
The biology of micrometastases from uveal melanoma NJ Borthwick, J Thombs, M Polak, FG Gabriel, JL Hungerford, B Damato, ... Journal of clinical pathology 64 (8), 666-671, 2011 | 34 | 2011 |
Molecular basis of chemosensitivity of platinum pre-treated ovarian cancer to chemotherapy S Glaysher, FG Gabriel, P Johnson, M Polak, LA Knight, K Parker, ... British journal of cancer 103 (5), 656-662, 2010 | 32 | 2010 |
Pilot studies of the effect of zoledronic acid (Zometa®) on tumor-derived cells ex vivo in the ATP-based tumor chemosensitivity assay LA Knight, M Conroy, A Fernando, M Polak, CM Kurbacher, IA Cree Anti-cancer drugs 16 (9), 969-976, 2005 | 32 | 2005 |
Presence and maturity of dendritic cells in melanoma lymph node metastases ME Polak, P Johnson, SD Palma, B Higgins, J Hurren, NJ Borthwick, ... The Journal of pathology 207 (1), 83-90, 2005 | 32 | 2005 |
Malaria systems immunology: Plasmodium vivax induces tolerance during primary infection through dysregulation of neutrophils and dendritic cells AF Vallejo, RC Read, M Arevalo-Herrera, S Herrera, T Elliott, ME Polak Journal of Infection 77 (5), 440-447, 2018 | 31 | 2018 |
A graphical and computational modeling platform for biological pathways A Livigni, L O'Hara, ME Polak, T Angus, DW Wright, LB Smith, ... Nature protocols 13 (4), 705-722, 2018 | 31 | 2018 |
The molecular basis of the chemosensitivity of metastatic cutaneous melanoma to chemotherapy KA Parker, S Glaysher, M Polak, FG Gabriel, P Johnson, LA Knight, ... Journal of clinical pathology 63 (11), 1012-1020, 2010 | 29 | 2010 |